JP2022519631A5 - - Google Patents

Info

Publication number
JP2022519631A5
JP2022519631A5 JP2021545677A JP2021545677A JP2022519631A5 JP 2022519631 A5 JP2022519631 A5 JP 2022519631A5 JP 2021545677 A JP2021545677 A JP 2021545677A JP 2021545677 A JP2021545677 A JP 2021545677A JP 2022519631 A5 JP2022519631 A5 JP 2022519631A5
Authority
JP
Japan
Prior art keywords
seq
amino acid
acid sequence
antigen
less
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2021545677A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022519631A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/017889 external-priority patent/WO2020167919A1/en
Publication of JP2022519631A publication Critical patent/JP2022519631A/ja
Publication of JP2022519631A5 publication Critical patent/JP2022519631A5/ja
Abandoned legal-status Critical Current

Links

JP2021545677A 2019-02-12 2020-02-12 補体および標的抗原に結合する二重特異性抗体を使用するための組成物および方法 Abandoned JP2022519631A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962804358P 2019-02-12 2019-02-12
US62/804,358 2019-02-12
PCT/US2020/017889 WO2020167919A1 (en) 2019-02-12 2020-02-12 Compositions and methods for using bispecific antibodies to bind complement and a target antigen

Publications (2)

Publication Number Publication Date
JP2022519631A JP2022519631A (ja) 2022-03-24
JP2022519631A5 true JP2022519631A5 (https=) 2023-02-17

Family

ID=69771250

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021545677A Abandoned JP2022519631A (ja) 2019-02-12 2020-02-12 補体および標的抗原に結合する二重特異性抗体を使用するための組成物および方法

Country Status (11)

Country Link
US (2) US12459991B2 (https=)
EP (1) EP3923978A1 (https=)
JP (1) JP2022519631A (https=)
KR (1) KR20210126641A (https=)
CN (1) CN113412121A (https=)
AU (1) AU2020223205A1 (https=)
CA (1) CA3127696A1 (https=)
IL (1) IL285404A (https=)
MA (1) MA54945A (https=)
MX (1) MX2021009533A (https=)
WO (1) WO2020167919A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230119179A (ko) * 2020-12-10 2023-08-16 우시 바이올로직스 아일랜드 리미티드 P-캐드히린에 대한 항체 및 이의 용도
WO2023201306A1 (en) 2022-04-14 2023-10-19 Invisishield Technologies Ltd. Compositions for preventing or treating influenza infections
CN116036091B (zh) * 2023-03-03 2025-05-27 中国药科大学 巴洛沙韦酯或巴洛沙韦酸作为vista激动剂的医药用途及其药物组合物
WO2025229160A1 (en) 2024-05-01 2025-11-06 Commit Biologics Aps Engineered proteins that engage complement factor and a protein antigen, methods, and uses thereof

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
US7087411B2 (en) 1999-06-08 2006-08-08 Regeneron Pharmaceuticals, Inc. Fusion protein capable of binding VEGF
US6596541B2 (en) 2000-10-31 2003-07-22 Regeneron Pharmaceuticals, Inc. Methods of modifying eukaryotic cells
PT1377314E (pt) 2001-01-26 2012-01-02 Inhibitex Inc Anticorpos monoclonais para a proteína clfa e método de utilização no tratamento ou prevenção de infecções
US7850962B2 (en) 2004-04-20 2010-12-14 Genmab A/S Human monoclonal antibodies against CD20
ES2415358T3 (es) 2004-04-21 2013-07-25 The Brigham And Women's Hospital, Inc. Péptidos de fijación a la poli-N-acetil glucosamina (PNAG/DPNAG) y procedimientos para el uso de los mismos
AU2005313971B2 (en) 2004-12-08 2011-10-13 Immunomedics, Inc. Methods and compositions for immunotherapy and detection of inflammatory and immune-dysregulatory disease, infectious disease, pathologic angiogenesis and cancer
JP5307708B2 (ja) 2006-06-02 2013-10-02 リジェネロン・ファーマシューティカルズ・インコーポレイテッド ヒトil−6受容体に対する高親和性抗体
ES2593484T3 (es) 2007-03-29 2016-12-09 Genmab A/S Anticuerpos biespecíficos y métodos de producción de los mismos
WO2009029132A2 (en) 2007-05-31 2009-03-05 Merck & Co., Inc. Antigen-binding proteins targeting s. aureus orf0657n
ES3000111T3 (en) 2009-02-13 2025-02-27 Immunomedics Inc Intermediates for preparing conjugates with an intracellularly-cleavable linkage
MY192182A (en) 2009-06-26 2022-08-04 Regeneron Pharma Readily isolated bispecific antibodies with native immunoglobulin format
SMT202600080T1 (it) 2010-02-08 2026-03-09 Regeneron Pharma Topo con catena leggera comune
RU2014100111A (ru) 2011-06-10 2015-07-20 МЕДИММЬЮН, ЭлЭлСи МОЛЕКУЛЫ, СВЯЗЫВАЮЩИЕСЯ С Psl Pseudomonas, И ПУТИ ИХ ПРИМЕНЕНИЯ
WO2013039954A1 (en) 2011-09-14 2013-03-21 Sanofi Anti-gitr antibodies
US9988439B2 (en) 2011-12-23 2018-06-05 Nicholas B. Lydon Immunoglobulins and variants directed against pathogenic microbes
WO2013096948A1 (en) * 2011-12-23 2013-06-27 Lydon Nicholas B Immunoglobulins and variants directed against pathogenic microbes
US20140212409A1 (en) 2012-08-13 2014-07-31 Kyowa Hakko Kirin Co., Ltd. METHOD FOR INCREASING DEPOSITION OF COMPLEMENT C3b ON BACTERIAL SURFACE AND PHAGOCYTOSIS BY PHAGOCYTE AND A THERAPEUTIC METHOD AND A THERAPEUTIC AGENT FOR BACTERIAL INFECTIONS
JOP20200236A1 (ar) 2012-09-21 2017-06-16 Regeneron Pharma الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
BR112015010125A2 (pt) 2012-11-06 2017-08-22 Medimmune Llc Anticorpo isolado ou seu fragmento de ligação, composição, ácido nucleico isolado, métodos de determinação da presença de s. aureus em uma amostra de teste, de tratamento de uma infecção por s. aureus em um paciente, de prevenção ou redução da gravidade de sepsia associada a s. aureus em um paciente, de atraso do início de sepsia associada a infecção por s. aureus em um paciente, de prevenção do início de sepsia associada a infecção por s. aureus em um paciente, de redução de carga bacteriana de s. aureus na corrente sanguínea ou coração em um paciente, e de redução da aglutinação bacteriana de s. aureus e/ou formação de lesões tromboembólicas em um paciente
TWI635098B (zh) 2013-02-01 2018-09-11 再生元醫藥公司 含嵌合恆定區之抗體
TWI701042B (zh) 2014-03-19 2020-08-11 美商再生元醫藥公司 用於腫瘤治療之方法及抗體組成物
WO2015187779A1 (en) 2014-06-03 2015-12-10 Xbiotech, Inc. Compositions and methods for treating and preventing staphylococcus aureus infections
KR102614189B1 (ko) 2014-11-17 2023-12-18 리제너론 파아마슈티컬스, 인크. Cd3xcd20 이특이적 항체를 이용한 종양의 치료 방법
TWI702229B (zh) 2014-12-19 2020-08-21 美商再生元醫藥公司 流行性感冒病毒血球凝集素之人類抗體
WO2016161010A2 (en) 2015-03-30 2016-10-06 Regeneron Pharmaceuticals, Inc. Heavy chain constant regions with reduced binding to fc gamma receptors
CN109563170B (zh) 2016-06-10 2023-10-13 瑞泽恩制药公司 抗gitr抗体及其用途
TWI781130B (zh) 2017-01-03 2022-10-21 美商再生元醫藥公司 抗金黃色葡萄球菌溶血素a毒素之人類抗體
CA3076632A1 (en) 2017-09-29 2019-04-04 Regeneron Pharmaceuticals, Inc. Bispecific antigen-binding molecules that bind a staphylococcus target antigen and a complement component and uses thereof

Similar Documents

Publication Publication Date Title
JP2023002562A5 (https=)
JP2024038003A5 (https=)
JP2024020298A5 (https=)
JP2022519631A5 (https=)
JP2025131696A5 (https=)
JP2021531005A5 (https=)
JP2021521843A5 (https=)
JP2012532851A5 (https=)
JP2013542194A5 (https=)
JP2017505125A5 (https=)
JP2021524256A5 (https=)
JP2018035138A5 (https=)
JP2015535828A5 (https=)
CN110536903A (zh) 抗ox40抗体及其用途
RU2011105062A (ru) Нейтрализующие антитела против вируса гриппа а и их использование
JP2017535257A5 (https=)
RU2020130795A (ru) Нейтрализующие антитела к env вич-1 и их применение
JP2015503909A5 (https=)
RU2012112829A (ru) Анти-gitr-антитела
JP2015514110A5 (https=)
JP2010516229A5 (https=)
RU2018120695A (ru) Связывающие молекулы, специфичные в отношении asct2, и их применения
JP2017512759A5 (https=)
JP2024024114A5 (https=)
JP2022516351A5 (https=)