JP2022518944A5 - - Google Patents

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Publication number
JP2022518944A5
JP2022518944A5 JP2021544351A JP2021544351A JP2022518944A5 JP 2022518944 A5 JP2022518944 A5 JP 2022518944A5 JP 2021544351 A JP2021544351 A JP 2021544351A JP 2021544351 A JP2021544351 A JP 2021544351A JP 2022518944 A5 JP2022518944 A5 JP 2022518944A5
Authority
JP
Japan
Prior art keywords
diazaspiro
trifluoroethoxy
decane
pyrimidine
biphenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021544351A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022518944A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2020/000074 external-priority patent/WO2020157577A1/en
Publication of JP2022518944A publication Critical patent/JP2022518944A/ja
Publication of JP2022518944A5 publication Critical patent/JP2022518944A5/ja
Pending legal-status Critical Current

Links

JP2021544351A 2019-01-30 2020-01-30 肺動脈性肺高血圧症を治療するための投与レジメンおよび方法 Pending JP2022518944A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962798827P 2019-01-30 2019-01-30
US62/798,827 2019-01-30
PCT/IB2020/000074 WO2020157577A1 (en) 2019-01-30 2020-01-30 A dosage regime and method for treating pulmonary arterial hypertension with rodatristat ethyl

Publications (2)

Publication Number Publication Date
JP2022518944A JP2022518944A (ja) 2022-03-17
JP2022518944A5 true JP2022518944A5 (enExample) 2022-12-19

Family

ID=70285725

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021544351A Pending JP2022518944A (ja) 2019-01-30 2020-01-30 肺動脈性肺高血圧症を治療するための投与レジメンおよび方法

Country Status (9)

Country Link
US (2) US11607413B2 (enExample)
EP (1) EP3917531A1 (enExample)
JP (1) JP2022518944A (enExample)
KR (1) KR20210133953A (enExample)
CN (1) CN113557022A (enExample)
AU (1) AU2020213746A1 (enExample)
CA (1) CA3128327A1 (enExample)
MX (1) MX2021009055A (enExample)
WO (1) WO2020157577A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3119912A1 (en) * 2018-11-14 2020-05-22 Altavant Sciences Gmbh A crystalline spirocyclic compound inhibitor of tryptophan hydroxylase 1 (tph1) for treating diseases or disorders associated with peripheral serotonin
US11413287B2 (en) * 2018-11-16 2022-08-16 Altavant Sciences Gmbh Method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension
WO2020128614A1 (en) * 2018-12-17 2020-06-25 Altavant Sciences Gmbh Method for treating interstital lung disease
MX2021009055A (es) 2019-01-30 2021-10-22 Altavant Sciences Gmbh Pauta posológica y método para tratar la hipertensión arterial pulmonar con rodatristat etilo.
AU2020244278A1 (en) * 2019-03-15 2021-09-30 Altavant Sciences Gmbh A method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension and daily dosing
WO2023062595A1 (en) 2021-10-14 2023-04-20 Altavant Sciences Gmbh Treatment of subjects having pulmonary arterial hypertension with rodatristat ethyl

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7875622B2 (en) 2007-07-11 2011-01-25 Lexicon Pharmaceuticals, Inc. Methods and compositions for treating pulmonary hypertension and related diseases and disorders
UA119247C2 (uk) 2013-09-06 2019-05-27 РОЙВЕНТ САЙЕНСИЗ ҐмбГ Спіроциклічні сполуки як інгібітори триптофангідроксилази
CA3119912A1 (en) * 2018-11-14 2020-05-22 Altavant Sciences Gmbh A crystalline spirocyclic compound inhibitor of tryptophan hydroxylase 1 (tph1) for treating diseases or disorders associated with peripheral serotonin
US11413287B2 (en) 2018-11-16 2022-08-16 Altavant Sciences Gmbh Method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension
WO2020128614A1 (en) 2018-12-17 2020-06-25 Altavant Sciences Gmbh Method for treating interstital lung disease
WO2020128608A1 (en) 2018-12-17 2020-06-25 Altavant Sciences Gmbh Compound for use in a method for treating sarcoidosis-associated pulmonary hypertension
MX2021009055A (es) 2019-01-30 2021-10-22 Altavant Sciences Gmbh Pauta posológica y método para tratar la hipertensión arterial pulmonar con rodatristat etilo.
AU2020244278A1 (en) * 2019-03-15 2021-09-30 Altavant Sciences Gmbh A method for treating pulmonary arterial hypertension and associated pulmonary arterial hypertension and daily dosing

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