|
US5126A
(en)
|
|
1847-05-22 |
|
Cast-iron cab-wheel |
|
US170A
(en)
|
|
1837-04-20 |
|
Improvement in concentrating-furnaces for smelting iron ores by the use of anthracite |
|
US5912A
(en)
|
|
1848-11-07 |
|
Lamp-wicks |
|
US132A
(en)
|
|
1837-02-25 |
|
Improvement in propelling machinery by magnetism and electro-magnetism |
|
US5833975A
(en)
|
1989-03-08 |
1998-11-10 |
Virogenetics Corporation |
Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence
|
|
US5766920A
(en)
|
1982-08-11 |
1998-06-16 |
Cellcor, Inc. |
Ex vivo activation of immune cells
|
|
US4588585A
(en)
|
1982-10-19 |
1986-05-13 |
Cetus Corporation |
Human recombinant cysteine depleted interferon-β muteins
|
|
US4703004A
(en)
|
1984-01-24 |
1987-10-27 |
Immunex Corporation |
Synthesis of protein with an identification peptide
|
|
US4751180A
(en)
|
1985-03-28 |
1988-06-14 |
Chiron Corporation |
Expression using fused genes providing for protein product
|
|
US4935233A
(en)
|
1985-12-02 |
1990-06-19 |
G. D. Searle And Company |
Covalently linked polypeptide cell modulators
|
|
WO1988000970A2
(en)
|
1986-08-08 |
1988-02-11 |
Regents Of The University Of Minnesota |
Method of culturing leukocytes
|
|
US4851341A
(en)
|
1986-12-19 |
1989-07-25 |
Immunex Corporation |
Immunoaffinity purification system
|
|
CA1341245C
(en)
|
1988-01-12 |
2001-06-05 |
F. Hoffmann-La Roche Ag |
Recombinant vaccinia virus mva
|
|
US5906936A
(en)
|
1988-05-04 |
1999-05-25 |
Yeda Research And Development Co. Ltd. |
Endowing lymphocytes with antibody specificity
|
|
US6780407B1
(en)
|
1989-03-08 |
2004-08-24 |
Aventis Pasteur |
Pox virus comprising DNA sequences encoding CEA and B7 antigen
|
|
US5126132A
(en)
|
1989-08-21 |
1992-06-30 |
The United States Of America As Represented By The Department Of Health And Human Services |
Tumor infiltrating lymphocytes as a treatment modality for human cancer
|
|
US5728388A
(en)
|
1989-10-03 |
1998-03-17 |
Terman; David S. |
Method of cancer treatment
|
|
US6309647B1
(en)
|
1999-07-15 |
2001-10-30 |
Aventis Pasteur |
Poxvirus—canine dispemper virus (CDV) or measles virus recombinants and compositions and methods employing the recombinants
|
|
US6277558B1
(en)
|
1990-11-30 |
2001-08-21 |
Kansas University Medical Center |
α-3 chain type IV collagen polynucleotides
|
|
US5851828A
(en)
|
1991-03-07 |
1998-12-22 |
The General Hospital Corporation |
Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
|
|
US6004811A
(en)
|
1991-03-07 |
1999-12-21 |
The Massachussetts General Hospital |
Redirection of cellular immunity by protein tyrosine kinase chimeras
|
|
IE920716A1
(en)
|
1991-03-07 |
1992-09-09 |
Gen Hospital Corp |
Redirection of cellular immunity by receptor chimeras
|
|
US5843728A
(en)
|
1991-03-07 |
1998-12-01 |
The General Hospital Corporation |
Redirection of cellular immunity by receptor chimeras
|
|
US6753162B1
(en)
|
1991-03-07 |
2004-06-22 |
The General Hospital Corporation |
Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells
|
|
US5912170A
(en)
|
1991-03-07 |
1999-06-15 |
The General Hospital Corporation |
Redirection of cellular immunity by protein-tyrosine kinase chimeras
|
|
JP3029135B2
(ja)
|
1991-04-23 |
2000-04-04 |
キヤノン株式会社 |
文字処理装置及び方法
|
|
IL104570A0
(en)
|
1992-03-18 |
1993-05-13 |
Yeda Res & Dev |
Chimeric genes and cells transformed therewith
|
|
US8211422B2
(en)
|
1992-03-18 |
2012-07-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric receptor genes and cells transformed therewith
|
|
DE4237113B4
(de)
|
1992-11-03 |
2006-10-12 |
"Iba Gmbh" |
Peptide und deren Fusionsproteine, Expressionsvektor und Verfahren zur Herstellung eines Fusionsproteins
|
|
US6991797B2
(en)
|
1993-07-02 |
2006-01-31 |
Statens Serum Institut |
M. tuberculosis antigens
|
|
US5874239A
(en)
|
1993-07-30 |
1999-02-23 |
Affymax Technologies N.V. |
Biotinylation of proteins
|
|
EP0726941B1
(en)
|
1993-08-06 |
2002-04-03 |
Epimmune Inc. |
Methods for (ex vivo) therapy using peptide-loaded antigen presenting cells for the activation of ctl
|
|
US5658785A
(en)
|
1994-06-06 |
1997-08-19 |
Children's Hospital, Inc. |
Adeno-associated virus materials and methods
|
|
US5827642A
(en)
|
1994-08-31 |
1998-10-27 |
Fred Hutchinson Cancer Research Center |
Rapid expansion method ("REM") for in vitro propagation of T lymphocytes
|
|
US6924128B2
(en)
|
1994-12-06 |
2005-08-02 |
Targeted Genetics Corporation |
Packaging cell lines for generation of high titers of recombinant AAV vectors
|
|
US5712149A
(en)
|
1995-02-03 |
1998-01-27 |
Cell Genesys, Inc. |
Chimeric receptor molecules for delivery of co-stimulatory signals
|
|
US5635363A
(en)
|
1995-02-28 |
1997-06-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compositions and methods for the detection, quantitation and purification of antigen-specific T cells
|
|
CA2214649C
(en)
|
1995-03-08 |
2007-06-12 |
Zeling Cai |
Antigen presenting system and methods for activation of t-cells
|
|
US6013516A
(en)
|
1995-10-06 |
2000-01-11 |
The Salk Institute For Biological Studies |
Vector and method of use for nucleic acid delivery to non-dividing cells
|
|
JPH11511376A
(ja)
|
1996-03-13 |
1999-10-05 |
アナロジック コーポレーション |
コンピュータ・トモグラフィの自己校正リング抑制フィルタ
|
|
US6090393A
(en)
|
1996-07-03 |
2000-07-18 |
Merial |
Recombinant canine adenoviruses, method for making and uses thereof
|
|
US6156567A
(en)
|
1996-07-03 |
2000-12-05 |
Merial |
Truncated transcriptionally active cytomegalovirus promoters
|
|
PT904392E
(pt)
|
1996-10-17 |
2001-06-29 |
Oxford Biomedica Ltd |
Vectores retrovirais
|
|
US7198784B2
(en)
|
1996-10-17 |
2007-04-03 |
Oxford Biomedica (Uk) Limited |
Retroviral vectors
|
|
US7255862B1
(en)
|
1996-11-14 |
2007-08-14 |
Connaught Technology Corporation |
ALVAC/FIV constructs
|
|
CA2278847A1
(en)
|
1997-01-31 |
1998-08-06 |
Hemosol Inc. |
Method for the production of selected lymphocytes
|
|
ATE466948T1
(de)
|
1997-03-11 |
2010-05-15 |
Univ Minnesota |
Dns-basiertes transposon-system für die einführung von nucleinsäure in die dns einer zelle
|
|
WO1999014354A1
(en)
|
1997-09-19 |
1999-03-25 |
The Trustees Of The University Of The Pennsylvania |
Methods and vector constructs useful for production of recombinant aav
|
|
EP1015619A1
(en)
|
1997-09-19 |
2000-07-05 |
The Trustees Of The University Of Pennsylvania |
Methods and cell line useful for production of recombinant adeno-associated viruses
|
|
GB9720465D0
(en)
|
1997-09-25 |
1997-11-26 |
Oxford Biomedica Ltd |
Dual-virus vectors
|
|
US6346415B1
(en)
|
1997-10-21 |
2002-02-12 |
Targeted Genetics Corporation |
Transcriptionally-activated AAV inverted terminal repeats (ITRS) for use with recombinant AAV vectors
|
|
US5994136A
(en)
|
1997-12-12 |
1999-11-30 |
Cell Genesys, Inc. |
Method and means for producing high titer, safe, recombinant lentivirus vectors
|
|
US6953690B1
(en)
|
1998-03-20 |
2005-10-11 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
AU780231B2
(en)
|
1998-11-10 |
2005-03-10 |
University Of North Carolina At Chapel Hill, The |
Virus vectors and methods of making and administering the same
|
|
US7160682B2
(en)
|
1998-11-13 |
2007-01-09 |
Regents Of The University Of Minnesota |
Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell
|
|
US6258595B1
(en)
|
1999-03-18 |
2001-07-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for helper-free production of recombinant adeno-associated viruses
|
|
US6893865B1
(en)
|
1999-04-28 |
2005-05-17 |
Targeted Genetics Corporation |
Methods, compositions, and cells for encapsidating recombinant vectors in AAV particles
|
|
US6913922B1
(en)
|
1999-05-18 |
2005-07-05 |
Crucell Holland B.V. |
Serotype of adenovirus and uses thereof
|
|
US6492169B1
(en)
|
1999-05-18 |
2002-12-10 |
Crucell Holland, B.V. |
Complementing cell lines
|
|
US6793926B1
(en)
|
1999-05-27 |
2004-09-21 |
Genovo, Inc. |
Methods for production of a recombinant adeno-associated virus
|
|
DK1180159T3
(da)
|
1999-05-28 |
2008-11-17 |
Targeted Genetics Corp |
Fremgangsmåder og sammensætninger til at sænke niveauet af Tumor-Nekrose-Faktor (TNF) i TNF-associerede lidelser
|
|
US6955808B2
(en)
|
1999-09-24 |
2005-10-18 |
Uab Research Foundation |
Capsid-modified recombinant adenovirus and methods of use
|
|
US7115391B1
(en)
|
1999-10-01 |
2006-10-03 |
Genovo, Inc. |
Production of recombinant AAV using adenovirus comprising AAV rep/cap genes
|
|
IL151860A0
(en)
|
2000-03-27 |
2003-04-10 |
Technion Res & Dev Foundation |
Single chain class i major histocompatibility complexes, constructs encoding same and methods of generating same
|
|
GB0024550D0
(https=)
|
2000-10-06 |
2000-11-22 |
Oxford Biomedica Ltd |
|
|
NZ526489A
(en)
|
2000-12-15 |
2007-07-27 |
Balwinder Singh Aulakh |
An in vivo method for producing female offsprings in mammals using a material comprising acetic acid
|
|
GB0202334D0
(en)
|
2001-04-05 |
2002-03-20 |
Nextgen Sciences Ltd |
Protein analysis
|
|
IL160359A0
(en)
|
2001-08-31 |
2004-07-25 |
Avidex Ltd |
Soluble t cell receptor
|
|
WO2003089618A2
(en)
|
2002-04-22 |
2003-10-30 |
Regents Of The University Of Minnesota |
Transposon system and methods of use
|
|
CA2501870C
(en)
|
2002-10-09 |
2013-07-02 |
Avidex Limited |
Single chain recombinant t cell receptors
|
|
PT1558643E
(pt)
|
2002-11-09 |
2009-08-24 |
Immunocore Ltd |
Apresentação de um receptor das células t
|
|
GB0304068D0
(en)
|
2003-02-22 |
2003-03-26 |
Avidex Ltd |
Substances
|
|
US7985739B2
(en)
|
2003-06-04 |
2011-07-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Enhanced sleeping beauty transposon system and methods for using the same
|
|
US7435596B2
(en)
|
2004-11-04 |
2008-10-14 |
St. Jude Children's Research Hospital, Inc. |
Modified cell line and method for expansion of NK cell
|
|
AU2005219876A1
(en)
*
|
2004-03-01 |
2005-09-15 |
Peptimmune, Inc. |
Methods and compositions for treatment of autoimmune diseases
|
|
JP5191729B2
(ja)
|
2004-03-11 |
2013-05-08 |
フレゼニウス・カビ・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング |
還元的アミノ化によって製造される、ヒドロキシアルキルデンプンとタンパク質とのコンジュゲート
|
|
AU2005246073B2
(en)
|
2004-05-19 |
2010-10-28 |
Adaptimmune Limited |
Method of improving T cell receptors
|
|
ATE417065T1
(de)
|
2004-05-19 |
2008-12-15 |
Medigene Ltd |
Hochaffiner ny-eso-t-zellen-rezeptor
|
|
ATE475669T1
(de)
|
2004-06-29 |
2010-08-15 |
Immunocore Ltd |
Einen modifizierten t-zellen-rezeptor exprimierende zellen
|
|
FR2881746B1
(fr)
*
|
2005-02-07 |
2007-04-13 |
Centre Nat Rech Scient |
Epitopes t cd4+des antigenes de latence de type i et ii du virus epstein-barr aptes a etre reconnus par la majorite des individus de la population caucasienne et leurs applications
|
|
MX2007010008A
(es)
|
2005-02-16 |
2008-01-18 |
Lentigen Corp |
Vectores lentivirales y su uso.
|
|
UY29460A1
(es)
|
2005-04-08 |
2006-11-30 |
Noxxon Pharma Ag |
Acidos nucleicos de union a ghrelin
|
|
WO2006125962A2
(en)
|
2005-05-25 |
2006-11-30 |
Medigene Limited |
T cell receptors which specifically bind to vygfvracl-hla-a24
|
|
GB2442048B
(en)
|
2006-07-25 |
2009-09-30 |
Proimmune Ltd |
Biotinylated MHC complexes and their uses
|
|
US8088379B2
(en)
|
2006-09-26 |
2012-01-03 |
The United States Of America As Represented By The Department Of Health And Human Services |
Modified T cell receptors and related materials and methods
|
|
EP2087000A2
(en)
|
2006-09-29 |
2009-08-12 |
Immunocore Ltd. |
T cell therapies
|
|
DK2352756T3
(da)
|
2008-11-24 |
2012-12-03 |
Helmholtz Zentrum Muenchen |
Højaffin T-cellereceptor og anvendelse af denne
|
|
EP2493921B1
(en)
|
2009-10-30 |
2018-09-26 |
Albumedix Ltd |
Albumin variants
|
|
US9862927B2
(en)
|
2010-01-22 |
2018-01-09 |
Baylor Research Institute |
Dendritic cell vaccines
|
|
US9089520B2
(en)
|
2010-05-21 |
2015-07-28 |
Baylor College Of Medicine |
Methods for inducing selective apoptosis
|
|
WO2011148194A1
(en)
|
2010-05-28 |
2011-12-01 |
Oxford Biomedica (Uk) Ltd |
Delivery of lentiviral vectors to the brain
|
|
US9405700B2
(en)
|
2010-11-04 |
2016-08-02 |
Sonics, Inc. |
Methods and apparatus for virtualization in an integrated circuit
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
US8999937B2
(en)
|
2011-02-28 |
2015-04-07 |
Indiana University Research And Technology Corporation |
Glucocorticoid induced leucine zipper mimetics as therapeutic agents in multiple sclerosis
|
|
US20130071414A1
(en)
|
2011-04-27 |
2013-03-21 |
Gianpietro Dotti |
Engineered cd19-specific t lymphocytes that coexpress il-15 and an inducible caspase-9 based suicide gene for the treatment of b-cell malignancies
|
|
AU2012257377B2
(en)
|
2011-05-17 |
2017-09-07 |
Hadasit Medical Research Services And Development Ltd. |
Allogeneic tumor cell vaccination
|
|
US20120295960A1
(en)
|
2011-05-20 |
2012-11-22 |
Oxford Biomedica (Uk) Ltd. |
Treatment regimen for parkinson's disease
|
|
PL3892295T3
(pl)
|
2011-05-24 |
2023-07-24 |
BioNTech SE |
Zindywidualizowane szczepionki przeciwnowotworowe
|
|
WO2012159643A1
(en)
|
2011-05-24 |
2012-11-29 |
Biontech Ag |
Individualized vaccines for cancer
|
|
AU2012309830B2
(en)
|
2011-09-15 |
2017-03-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T cell receptors recognizing HLA-A1- or HLA-Cw7-restricted mage
|
|
EP3326467B1
(en)
|
2011-09-16 |
2020-03-11 |
Baylor College of Medicine |
Targeting the tumor microenvironment using manipulated nkt cells
|
|
EP2844743B1
(en)
|
2012-05-03 |
2021-01-13 |
Fred Hutchinson Cancer Research Center |
Enhanced affinity t cell receptors and methods for making the same
|
|
US20150140019A1
(en)
|
2012-07-13 |
2015-05-21 |
The Trustees Of The University Of Pennsylvania |
Compositions and Methods for Regulating CAR T Cells
|
|
KR102499753B1
(ko)
|
2012-07-27 |
2023-02-16 |
더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 |
Ｔ 세포 수용체 조작
|
|
GB2508414A
(en)
|
2012-11-30 |
2014-06-04 |
Max Delbrueck Centrum |
Tumour specific T cell receptors (TCRs)
|
|
CN113684185A
(zh)
|
2013-02-26 |
2021-11-23 |
纪念斯隆-凯特琳癌症中心 |
用于免疫疗法的组合物和方法
|
|
WO2015085147A1
(en)
|
2013-12-05 |
2015-06-11 |
The Broad Institute Inc. |
Polymorphic gene typing and somatic change detection using sequencing data
|
|
WO2016128060A1
(en)
*
|
2015-02-12 |
2016-08-18 |
Biontech Ag |
Predicting t cell epitopes useful for vaccination
|
|
ES2970865T3
(es)
*
|
2015-12-16 |
2024-05-31 |
Gritstone Bio Inc |
Identificación, fabricación y uso de neoantígenos
|
|
AU2017254477A1
(en)
*
|
2016-04-18 |
2018-11-01 |
Jennifer G. ABELIN |
Improved HLA epitope prediction
|
|
US20200182884A1
(en)
|
2016-06-27 |
2020-06-11 |
Juno Therapeutics, Inc. |
Method of identifying peptide epitopes, molecules that bind such epitopes and related uses
|
|
US11965892B2
(en)
*
|
2017-02-12 |
2024-04-23 |
Biontech Us Inc. |
HLA-based methods and compositions and uses thereof
|
|
JP7155470B2
(ja)
*
|
2017-03-31 |
2022-10-19 |
エーシーティー ジェノミックス （アイピー） カンパニー リミテッド |
免疫原性がん特異的エピトープのためのランク付けシステム
|
|
CA3060569A1
(en)
*
|
2017-04-19 |
2018-10-25 |
Gritstone Oncology, Inc. |
Neoantigen identification, manufacture, and use
|
|
EP4197552A1
(en)
*
|
2018-03-12 |
2023-06-21 |
The Children's Hospital of Philadelphia |
Methods and compositions for use of tumor self-antigens in adoptive immunotherapy
|