JP2022517902A5 - - Google Patents

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Publication number
JP2022517902A5
JP2022517902A5 JP2021529088A JP2021529088A JP2022517902A5 JP 2022517902 A5 JP2022517902 A5 JP 2022517902A5 JP 2021529088 A JP2021529088 A JP 2021529088A JP 2021529088 A JP2021529088 A JP 2021529088A JP 2022517902 A5 JP2022517902 A5 JP 2022517902A5
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JP
Japan
Application number
JP2021529088A
Other languages
Japanese (ja)
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JP7490647B2 (ja
JP2022517902A (ja
JPWO2020103859A5 (https=
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Priority claimed from PCT/CN2019/119676 external-priority patent/WO2020103859A1/en
Publication of JP2022517902A publication Critical patent/JP2022517902A/ja
Publication of JP2022517902A5 publication Critical patent/JP2022517902A5/ja
Publication of JPWO2020103859A5 publication Critical patent/JPWO2020103859A5/ja
Application granted granted Critical
Publication of JP7490647B2 publication Critical patent/JP7490647B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021529088A 2018-11-20 2019-11-20 Rip1阻害剤 Active JP7490647B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2018116555 2018-11-20
CNPCT/CN2018/116555 2018-11-20
PCT/CN2019/119676 WO2020103859A1 (en) 2018-11-20 2019-11-20 RIP1 Inhibitors

Publications (4)

Publication Number Publication Date
JP2022517902A JP2022517902A (ja) 2022-03-11
JP2022517902A5 true JP2022517902A5 (https=) 2022-11-07
JPWO2020103859A5 JPWO2020103859A5 (https=) 2022-11-07
JP7490647B2 JP7490647B2 (ja) 2024-05-27

Family

ID=70773337

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021529088A Active JP7490647B2 (ja) 2018-11-20 2019-11-20 Rip1阻害剤

Country Status (12)

Country Link
US (1) US12129221B2 (https=)
EP (1) EP3883918B1 (https=)
JP (1) JP7490647B2 (https=)
KR (1) KR102810898B1 (https=)
CN (1) CN113272272B (https=)
AU (1) AU2019384283B2 (https=)
CA (1) CA3120726C (https=)
CO (1) CO2021006480A2 (https=)
IL (1) IL283309B2 (https=)
MX (1) MX2021005944A (https=)
SG (1) SG11202105264UA (https=)
WO (1) WO2020103859A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4308555A4 (en) * 2021-03-18 2025-07-30 Sironax Ltd RECEPTOR-INTERACTING PROTEIN-1 INHIBITORS, PREPARATIONS AND USES THEREOF
US20240409501A1 (en) * 2021-10-22 2024-12-12 Sironax Ltd. Cyrstalline forms of rip1 inhibitor
US11541116B1 (en) 2022-01-07 2023-01-03 Kojin Therapeutics, Inc. Methods and compositions for inducing ferroptosis in vivo

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405357A (en) * 1980-06-02 1983-09-20 Fmc Corporation Herbicidal 3-isoxazolidinones and hydroxamic acids
GB8820185D0 (en) * 1988-08-25 1988-09-28 Wellcome Found New medical use
US6756394B1 (en) 1999-10-15 2004-06-29 President And Fellow Of Harvard College Small molecule inhibitors of necrosis
US6706766B2 (en) 1999-12-13 2004-03-16 President And Fellows Of Harvard College Small molecules used to increase cell death
SI2384753T1 (sl) 2003-08-29 2016-06-30 The Brigham And Women's Hospital, Inc. Hidantoinski derivati kot inhibitorji celične nekroze
US20090099242A1 (en) 2007-08-15 2009-04-16 Cuny Gregory D Heterocyclic inhibitors of necroptosis
WO2010075290A1 (en) 2008-12-22 2010-07-01 President And Fellows Of Harvard College Unsaturated heterocyclic inhibitors of necroptosis
CA2772760A1 (en) 2008-12-23 2010-07-01 President And Fellows Of Harvard College Small molecule inhibitors of necroptosis
WO2012125544A2 (en) 2011-03-11 2012-09-20 President And Fellows Of Harvard College Necroptosis inhibitors and methods of use therefor
CN107108539A (zh) * 2014-09-15 2017-08-29 北京生命科学研究所 钠‑葡萄糖协同转运蛋白2(sglt‑2)抑制剂
HK1244792B (en) 2014-12-24 2019-07-12 北京生命科学研究所 Necrosis inhibitors
AU2015371822B2 (en) 2014-12-24 2020-04-09 National Institute Of Biological Sciences, Beijing Necrosis inhibitors
EP3612223B1 (en) * 2017-04-17 2024-07-31 National Institute Of Biological Sciences, Beijing Treating male senescence

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