JP2022517902A5 - - Google Patents
Info
- Publication number
- JP2022517902A5 JP2022517902A5 JP2021529088A JP2021529088A JP2022517902A5 JP 2022517902 A5 JP2022517902 A5 JP 2022517902A5 JP 2021529088 A JP2021529088 A JP 2021529088A JP 2021529088 A JP2021529088 A JP 2021529088A JP 2022517902 A5 JP2022517902 A5 JP 2022517902A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- pharmaceutically acceptable
- ferroptosis
- stereoisomers
- hydrates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2018116555 | 2018-11-20 | ||
| CNPCT/CN2018/116555 | 2018-11-20 | ||
| PCT/CN2019/119676 WO2020103859A1 (en) | 2018-11-20 | 2019-11-20 | RIP1 Inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022517902A JP2022517902A (ja) | 2022-03-11 |
| JP2022517902A5 true JP2022517902A5 (enExample) | 2022-11-07 |
| JP7490647B2 JP7490647B2 (ja) | 2024-05-27 |
Family
ID=70773337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021529088A Active JP7490647B2 (ja) | 2018-11-20 | 2019-11-20 | Ｒｉｐ１阻害剤 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US12129221B2 (enExample) |
| EP (1) | EP3883918B1 (enExample) |
| JP (1) | JP7490647B2 (enExample) |
| KR (1) | KR102810898B1 (enExample) |
| CN (1) | CN113272272B (enExample) |
| AU (1) | AU2019384283B2 (enExample) |
| CA (1) | CA3120726C (enExample) |
| CO (1) | CO2021006480A2 (enExample) |
| IL (1) | IL283309B2 (enExample) |
| MX (1) | MX2021005944A (enExample) |
| SG (1) | SG11202105264UA (enExample) |
| WO (1) | WO2020103859A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2024512931A (ja) * | 2021-03-18 | 2024-03-21 | シロナックス リミテッド． | 受容体相互作用タンパク質１阻害剤、その調製、及び使用 |
| CN118139841A (zh) * | 2021-10-22 | 2024-06-04 | 维泰瑞隆有限公司 | Rip1抑制剂的结晶形式 |
| US11541116B1 (en) | 2022-01-07 | 2023-01-03 | Kojin Therapeutics, Inc. | Methods and compositions for inducing ferroptosis in vivo |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4405357A (en) * | 1980-06-02 | 1983-09-20 | Fmc Corporation | Herbicidal 3-isoxazolidinones and hydroxamic acids |
| GB8820185D0 (en) * | 1988-08-25 | 1988-09-28 | Wellcome Found | New medical use |
| US6756394B1 (en) | 1999-10-15 | 2004-06-29 | President And Fellow Of Harvard College | Small molecule inhibitors of necrosis |
| US6706766B2 (en) | 1999-12-13 | 2004-03-16 | President And Fellows Of Harvard College | Small molecules used to increase cell death |
| DK2384753T3 (en) | 2003-08-29 | 2016-04-11 | Brigham & Womens Hospital | Hydantoin derivatives as inhibitors of cell necrosis |
| CA2696349A1 (en) | 2007-08-15 | 2009-02-19 | President And Fellows Of Harvard College | Heterocyclic inhibitors of necroptosis |
| WO2010075290A1 (en) | 2008-12-22 | 2010-07-01 | President And Fellows Of Harvard College | Unsaturated heterocyclic inhibitors of necroptosis |
| BRPI0923126A2 (pt) | 2008-12-23 | 2021-09-08 | President And Fellows Of Harvard College | Compostos inibidores de molécula pequena de necroptose, uso e composição compreendendo os mesmos e método de diminuir necroptose |
| WO2012125544A2 (en) | 2011-03-11 | 2012-09-20 | President And Fellows Of Harvard College | Necroptosis inhibitors and methods of use therefor |
| CN107108539A (zh) * | 2014-09-15 | 2017-08-29 | 北京生命科学研究所 | 钠‑葡萄糖协同转运蛋白2(sglt‑2)抑制剂 |
| AU2015371824B2 (en) | 2014-12-24 | 2019-09-19 | National Institute Of Biological Sciences, Beijing | Necrosis inhibitors |
| JP6772141B2 (ja) * | 2014-12-24 | 2020-10-21 | ナショナル・インスティチュート・オブ・バイオロジカル・サイエンシズ，ベイジン | ネクローシス阻害薬 |
| WO2018192416A1 (en) * | 2017-04-17 | 2018-10-25 | National Institute Of Biological Sciences, Beijing | Treating Male Senescence |
-
2019
- 2019-11-20 CA CA3120726A patent/CA3120726C/en active Active
- 2019-11-20 MX MX2021005944A patent/MX2021005944A/es unknown
- 2019-11-20 IL IL283309A patent/IL283309B2/en unknown
- 2019-11-20 CN CN201980087301.3A patent/CN113272272B/zh active Active
- 2019-11-20 AU AU2019384283A patent/AU2019384283B2/en active Active
- 2019-11-20 JP JP2021529088A patent/JP7490647B2/ja active Active
- 2019-11-20 WO PCT/CN2019/119676 patent/WO2020103859A1/en not_active Ceased
- 2019-11-20 SG SG11202105264UA patent/SG11202105264UA/en unknown
- 2019-11-20 KR KR1020217018499A patent/KR102810898B1/ko active Active
- 2019-11-20 EP EP19887923.1A patent/EP3883918B1/en active Active
-
2021
- 2021-05-19 US US17/325,193 patent/US12129221B2/en active Active
- 2021-06-19 CO CONC2021/0006480A patent/CO2021006480A2/es unknown