JP2022517865A - Ｃｘｃｌ１機能に関与する疾患の治療のための組成物および方法 - Google Patents

Ｃｘｃｌ１機能に関与する疾患の治療のための組成物および方法 Download PDF

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JP2022517865A
JP2022517865A JP2021543528A JP2021543528A JP2022517865A JP 2022517865 A JP2022517865 A JP 2022517865A JP 2021543528 A JP2021543528 A JP 2021543528A JP 2021543528 A JP2021543528 A JP 2021543528A JP 2022517865 A JP2022517865 A JP 2022517865A
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antibody
cxcl1
antigen
amino acid
seq
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JPWO2020160022A5 (https=
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ジェイ ロッサ― チャールズ
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    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
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    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/521—Chemokines
    • G01N2333/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4 or KC
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    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
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    • G01N2800/00—Detection or diagnosis of diseases
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2021543528A 2019-01-28 2020-01-28 Ｃｘｃｌ１機能に関与する疾患の治療のための組成物および方法 Pending JP2022517865A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962797573P 2019-01-28 2019-01-28
US62/797,573 2019-01-28
PCT/US2020/015457 WO2020160022A1 (en) 2019-01-28 2020-01-28 Compositions and methods for treatment of diseases involving cxcl1 function

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JP2022517865A true JP2022517865A (ja) 2022-03-10
JPWO2020160022A5 JPWO2020160022A5 (https=) 2023-02-03
JP2022517865A5 JP2022517865A5 (https=) 2023-02-03

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US (3) US11292832B2 (https=)
EP (1) EP3917949A4 (https=)
JP (1) JP2022517865A (https=)
CN (1) CN113544143A (https=)
CA (1) CA3127943A1 (https=)
WO (1) WO2020160022A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3249959A1 (en) * 2022-01-27 2025-06-17 Chiome Bioscience Inc. ANTI-CXCL1 HUMAN ANTIBODY
WO2026060413A1 (en) * 2024-09-16 2026-03-19 Calgent Biotechnology Co., Ltd. Single chain antibodies and use thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007026895A1 (ja) * 2005-09-02 2007-03-08 Toray Industries, Inc. 尿路上皮ガンの検出用キットおよび方法
CN101261275A (zh) * 2008-01-23 2008-09-10 李力 一种用于早期卵巢癌诊断的检测试剂盒
WO2010050554A1 (ja) * 2008-10-31 2010-05-06 東レ株式会社 ヒトｃｘｃｌ１タンパク質の免疫学的測定方法
JP2016506720A (ja) * 2013-01-21 2016-03-07 アッヴィ・インコーポレイテッド 炎症性疾患のための抗ｔｎｆ及び抗ｉｌ１７併用治療薬バイオマーカー
JP2016528170A (ja) * 2013-05-17 2016-09-15 セントル ナショナル デ ラ ルシュルシュ サイエンティフィーク（シーエヌアールエス） 抗ｃｘｃｌ１抗体、抗ｃｘｃｌ７抗体および抗ｃｘｃｌ８抗体ならびにそれらの用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7858752B2 (en) 2006-12-05 2010-12-28 Abbott Laboratories Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
WO2010050552A1 (ja) 2008-10-29 2010-05-06 日本ゼオン株式会社 ニトリル共重合体ラテックス組成物およびニトリル共重合体ゴム組成物
US8900588B2 (en) 2010-01-08 2014-12-02 Les Laboratories Servier Methods for treating breast cancer
US9290570B2 (en) 2013-03-15 2016-03-22 Eli Lilly And Company Pan-ELR+ CXC Chemokine Antibodies
WO2019055776A2 (en) * 2017-09-14 2019-03-21 Rosser Charles COMPOSITIONS AND METHODS FOR TREATING DISEASES INVOLVING CXCL1 FUNCTION
US11603569B2 (en) * 2018-03-20 2023-03-14 Cedars-Sinai Medical Center Immune modulating genes for prognosis, diagnosis and treatment of metastatic disease, and drug identification methods thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007026895A1 (ja) * 2005-09-02 2007-03-08 Toray Industries, Inc. 尿路上皮ガンの検出用キットおよび方法
CN101261275A (zh) * 2008-01-23 2008-09-10 李力 一种用于早期卵巢癌诊断的检测试剂盒
WO2010050554A1 (ja) * 2008-10-31 2010-05-06 東レ株式会社 ヒトｃｘｃｌ１タンパク質の免疫学的測定方法
JP2016506720A (ja) * 2013-01-21 2016-03-07 アッヴィ・インコーポレイテッド 炎症性疾患のための抗ｔｎｆ及び抗ｉｌ１７併用治療薬バイオマーカー
JP2016528170A (ja) * 2013-05-17 2016-09-15 セントル ナショナル デ ラ ルシュルシュ サイエンティフィーク（シーエヌアールエス） 抗ｃｘｃｌ１抗体、抗ｃｘｃｌ７抗体および抗ｃｘｃｌ８抗体ならびにそれらの用途

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
THERANOSTICS, vol. 9, no. 3, JPN6024003851, 2019, pages 853 - 867, ISSN: 0005399943 *

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Publication number Publication date
US20240018229A1 (en) 2024-01-18
EP3917949A1 (en) 2021-12-08
CN113544143A (zh) 2021-10-22
EP3917949A4 (en) 2022-11-23
CA3127943A1 (en) 2020-08-06
US11292832B2 (en) 2022-04-05
US11760796B2 (en) 2023-09-19
WO2020160022A1 (en) 2020-08-06
US20210301007A1 (en) 2021-09-30
US20220267430A1 (en) 2022-08-25

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