JP2022516537A5 - - Google Patents

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Publication number
JP2022516537A5
JP2022516537A5 JP2021538362A JP2021538362A JP2022516537A5 JP 2022516537 A5 JP2022516537 A5 JP 2022516537A5 JP 2021538362 A JP2021538362 A JP 2021538362A JP 2021538362 A JP2021538362 A JP 2021538362A JP 2022516537 A5 JP2022516537 A5 JP 2022516537A5
Authority
JP
Japan
Prior art keywords
syndrome
agonist according
ampk agonist
mitochondrial
deficiency
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021538362A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022516537A (ja
JP7511564B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/069145 external-priority patent/WO2020142547A1/en
Publication of JP2022516537A publication Critical patent/JP2022516537A/ja
Publication of JP2022516537A5 publication Critical patent/JP2022516537A5/ja
Application granted granted Critical
Publication of JP7511564B2 publication Critical patent/JP7511564B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021538362A 2018-12-31 2019-12-31 ミトコンドリア機能不全を治療する方法及び配合物 Active JP7511564B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862786970P 2018-12-31 2018-12-31
US62/786,970 2018-12-31
PCT/US2019/069145 WO2020142547A1 (en) 2018-12-31 2019-12-31 Methods and formulations to treat mitochondrial dysfunction

Publications (3)

Publication Number Publication Date
JP2022516537A JP2022516537A (ja) 2022-02-28
JP2022516537A5 true JP2022516537A5 (enExample) 2023-01-04
JP7511564B2 JP7511564B2 (ja) 2024-07-05

Family

ID=71406802

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021538362A Active JP7511564B2 (ja) 2018-12-31 2019-12-31 ミトコンドリア機能不全を治療する方法及び配合物

Country Status (8)

Country Link
US (1) US12377077B2 (enExample)
EP (1) EP3906027A4 (enExample)
JP (1) JP7511564B2 (enExample)
KR (1) KR20210110636A (enExample)
CN (1) CN113347972B (enExample)
BR (1) BR112021012799A8 (enExample)
CA (1) CA3124838A1 (enExample)
WO (1) WO2020142547A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119013256A (zh) * 2022-01-25 2024-11-22 Evvia治疗公司 Ampk激动剂及其使用方法
WO2024036044A1 (en) * 2022-08-08 2024-02-15 The Johns Hopkins University Compositions and methods for treating and preventing metabolic disorders
KR20240109203A (ko) * 2022-12-29 2024-07-10 주식회사 엣진 레베르 유전성 시신경병증의 미토콘드리아 염기 변이 교정 시스템
WO2024209363A1 (en) * 2023-04-06 2024-10-10 Pfizer Inc. Substituted indazole propionic acid derivative compounds and uses thereof as ampk activators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012114204A2 (en) * 2011-02-15 2012-08-30 Ecole Polytechnique Federale De Lausanne (Epfl) Epfl-Tto Methods of treating mitochondrial dysfunction
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
WO2014180908A1 (en) 2013-05-08 2014-11-13 Deutsches Krebsforschungszentrum Acip/peptide-based inhibition of cancer cachexia
JP2016533385A (ja) 2013-08-22 2016-10-27 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft アルキニルアルコール及び使用方法
WO2018118808A1 (en) 2016-12-19 2018-06-28 The Broad Institute, Inc. Methods of treating autism spectrum disorders

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