JP2022514956A5 - - Google Patents

Info

Publication number
JP2022514956A5
JP2022514956A5 JP2021536372A JP2021536372A JP2022514956A5 JP 2022514956 A5 JP2022514956 A5 JP 2022514956A5 JP 2021536372 A JP2021536372 A JP 2021536372A JP 2021536372 A JP2021536372 A JP 2021536372A JP 2022514956 A5 JP2022514956 A5 JP 2022514956A5
Authority
JP
Japan
Prior art keywords
polymer
polymer nanocapsule
alkyl group
amino
positively charged
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021536372A
Other languages
English (en)
Japanese (ja)
Other versions
JP7795356B2 (ja
JP2022514956A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/068259 external-priority patent/WO2020139807A2/en
Publication of JP2022514956A publication Critical patent/JP2022514956A/ja
Publication of JP2022514956A5 publication Critical patent/JP2022514956A5/ja
Application granted granted Critical
Publication of JP7795356B2 publication Critical patent/JP7795356B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021536372A 2018-12-23 2019-12-23 細胞調節剤の送達のためのナノカプセル Active JP7795356B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862784503P 2018-12-23 2018-12-23
US62/784,503 2018-12-23
PCT/US2019/068259 WO2020139807A2 (en) 2018-12-23 2019-12-23 Nanocapsules for the delivery of cell modulating agents

Publications (3)

Publication Number Publication Date
JP2022514956A JP2022514956A (ja) 2022-02-16
JP2022514956A5 true JP2022514956A5 (cg-RX-API-DMAC7.html) 2023-01-05
JP7795356B2 JP7795356B2 (ja) 2026-01-07

Family

ID=69326704

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021536372A Active JP7795356B2 (ja) 2018-12-23 2019-12-23 細胞調節剤の送達のためのナノカプセル

Country Status (6)

Country Link
US (1) US20210322331A1 (cg-RX-API-DMAC7.html)
EP (1) EP3898978A2 (cg-RX-API-DMAC7.html)
JP (1) JP7795356B2 (cg-RX-API-DMAC7.html)
CN (1) CN113544270A (cg-RX-API-DMAC7.html)
AU (1) AU2019414331B2 (cg-RX-API-DMAC7.html)
WO (1) WO2020139807A2 (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115012221B (zh) * 2021-03-05 2023-08-08 北京化工大学 一种控制干细胞分化的纳米纤维材料及其制备方法和用途
CN112972703B (zh) * 2021-03-10 2023-04-28 河南大学 基因编辑纳米胶囊及其制备方法与应用
CN113201499A (zh) * 2021-04-22 2021-08-03 广州医科大学附属第三医院(广州重症孕产妇救治中心、广州柔济医院) Hbb基因cd17突变细胞及其制备方法与应用
CN117460518A (zh) * 2021-04-30 2024-01-26 宾夕法尼亚大学理事会 Cd-90靶向的脂质纳米颗粒
JP2026514876A (ja) * 2023-04-20 2026-05-13 パーデュー リサーチ ファウンデーション 標的化ペプチド担体システムを使用する核酸の送達

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100400509B1 (ko) 1995-03-27 2004-04-03 쥬가이 세이야쿠 가부시키가이샤 메토트렉세이트유도체를함유하는약제
WO2007098089A2 (en) 2006-02-17 2007-08-30 Novacea, Inc. Treatment of hyperproliferative diseases with methotrexate n-oxide and analogs
EP2406173A4 (en) 2009-03-09 2016-04-06 Univ California SINGLE PROTEIN NANOCAPSULES FOR PROTEIN RELIEF WITH LONG-TERM EFFECT
WO2013052158A2 (en) * 2011-04-26 2013-04-11 William Marsh Rice University Targeted nanovectors and their use for treatment of brain tumors
AU2013231839B2 (en) * 2012-03-16 2017-11-23 The Regents Of The University Of California A novel RNAi molecule delivery platform based on single-siRNA and shRNA nanocapsules
EP2997146A4 (en) * 2013-05-15 2017-04-26 Sangamo BioSciences, Inc. Methods and compositions for treatment of a genetic condition
WO2015089419A2 (en) * 2013-12-12 2015-06-18 The Broad Institute Inc. Delivery, use and therapeutic applications of the crispr-cas systems and compositions for targeting disorders and diseases using particle delivery components
KR20160097338A (ko) * 2013-12-12 2016-08-17 더 브로드 인스티튜트, 인코퍼레이티드 뉴클레오티드 반복 장애에서의 crispr-cas 시스템의 조성물 및 방법 및 용도
EP3247328B1 (en) 2015-01-21 2026-01-07 Genevant Sciences Gmbh Methods, compositions, and systems for delivering therapeutic and diagnostic agents into cells
US11279928B2 (en) * 2015-06-29 2022-03-22 Massachusetts Institute Of Technology Compositions comprising nucleic acids and methods of using the same
US20180237800A1 (en) * 2015-09-21 2018-08-23 The Regents Of The University Of California Compositions and methods for target nucleic acid modification
EP3463428A4 (en) * 2016-05-24 2020-01-08 The Regents of the University of California GROWTH FACTOR NANO CAPSULES WITH TUNABLE RELEASE FOR BONE REGENERATION
US20190209698A1 (en) * 2016-06-23 2019-07-11 University Of Massachusetts Polymeric nanoparticles and derivatives thereof for nucleic acid binding and delivery
EP3595629A4 (en) 2017-03-16 2021-01-06 Children's Medical Center Corporation NONVIRAL, NONCATIONIC NANOPARTICLE AND USES THEREOF
US11013695B2 (en) * 2017-08-28 2021-05-25 Wisconsin Alumni Research Foundation Nanocapsule delivery system for ribonucleoproteins

Similar Documents

Publication Publication Date Title
ES2308294T3 (es) Polimeros de poliamina.
JP5021160B2 (ja) pH−感受性ポリマー
Pan et al. Redox/pH dual stimuli-responsive biodegradable nanohydrogels with varying responses to dithiothreitol and glutathione for controlled drug release
ES2672153T3 (es) Composiciones farmcéuticas que comprenden poli(beta-amino-ésteres) biodegradables
Neu et al. Bioreversibly crosslinked polyplexes of PEI and high molecular weight PEG show extended circulation times in vivo
Sedlacek et al. Poly (2‐Oxazoline) s–Are They More Advantageous for Biomedical Applications Than Other Polymers?
US10632131B2 (en) Controlled release system
JP7038054B2 (ja) 粘膜付着型薬物送達のためのミセル
CN119546278A (zh) 两性离子在眼用局部乳膏组合物和制剂中的新应用
WO2014066912A1 (en) Polymeric nanoparticles
SI9620107A (sl) Blok polimer, ki ima funkcionalne skupine na obeh svojih koncih
Mathew et al. Hyperbranched PEGmethacrylate linear pDMAEMA block copolymer as an efficient non-viral gene delivery vector
JP2008518949A (ja) リン酸塩結合剤のための1日1回製剤
Cavallaro et al. Synthesis and characterization of polyaspartamide copolymers obtained by ATRP for nucleic acid delivery
JP7093975B2 (ja) 両性イオンポリマー、その製造方法、及び両性イオンポリマーを含むタンパク質安定化剤
Laaser et al. Architecture-Dependent Stabilization of Polyelectrolyte Complexes between Polyanions and Cationic Triblock Terpolymer Micelles
EP3675834A1 (en) Nanocapsules for delivering ribonucleoproteins
US20250108125A1 (en) Polymer nanoparticle compositions for non-viral gene delivery to the central nervous system
CA3232690A1 (en) Multi-motif dendrons and their supramolecular structures and uses thereof
JP6205364B2 (ja) 薬物徐放性眼用レンズ及びその製造方法
JP2010504318A5 (cg-RX-API-DMAC7.html)
RU2005100840A (ru) Фторсилоксановые матриксные системы доставки лекарств с регулируемой диффузией
CN104027816B (zh) 一种可去聚乙二醇化的共装载阿霉素和siRNA载体及其合成方法
WO2025250979A1 (en) Polymer nanoparticle compositions for non-viral gene delivery
US11007148B2 (en) Amphiphilic block copolymers for delivery of active agents