JP2022514954A5 - - Google Patents
Info
- Publication number
- JP2022514954A5 JP2022514954A5 JP2021536370A JP2021536370A JP2022514954A5 JP 2022514954 A5 JP2022514954 A5 JP 2022514954A5 JP 2021536370 A JP2021536370 A JP 2021536370A JP 2021536370 A JP2021536370 A JP 2021536370A JP 2022514954 A5 JP2022514954 A5 JP 2022514954A5
- Authority
- JP
- Japan
- Prior art keywords
- lymphocytes
- hprt
- expression vector
- pharmaceutical composition
- promoter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862784494P | 2018-12-23 | 2018-12-23 | |
| US62/784,494 | 2018-12-23 | ||
| PCT/US2019/068239 WO2020139800A1 (en) | 2018-12-23 | 2019-12-23 | Donor t-cells with kill switch |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022514954A JP2022514954A (ja) | 2022-02-16 |
| JP2022514954A5 true JP2022514954A5 (https=) | 2023-01-05 |
Family
ID=69326700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021536370A Pending JP2022514954A (ja) | 2018-12-23 | 2019-12-23 | キルスイッチを有するドナーｔ細胞 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20210340563A1 (https=) |
| EP (1) | EP3897831A1 (https=) |
| JP (1) | JP2022514954A (https=) |
| KR (1) | KR20210118833A (https=) |
| CN (1) | CN113543848A (https=) |
| AU (1) | AU2019417700A1 (https=) |
| BR (1) | BR112021012318A2 (https=) |
| CA (1) | CA3123045A1 (https=) |
| WO (1) | WO2020139800A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021263070A1 (en) * | 2020-06-26 | 2021-12-30 | Csl Behring Llc | Donor t-cells with kill switch |
| CN116162621B (zh) * | 2021-11-25 | 2025-09-16 | 中国科学院大连化学物理研究所 | Dna双链序列及应用和肺腺癌细胞增殖抑制剂或在肺腺癌药物 |
| CN115910357B (zh) * | 2022-11-14 | 2026-04-03 | 北京大学人民医院 | 预测HBsAg阳性患者造血干细胞移植后HBsAg清除的模型及装置 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5958928A (en) | 1995-03-27 | 1999-09-28 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical agents containing methotrexate derivative |
| US6013516A (en) | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
| EP1191097A1 (en) | 2000-09-21 | 2002-03-27 | Leids Universitair Medisch Centrum | Induction of exon skipping in eukaryotic cells |
| EP2933332A1 (en) | 2004-06-28 | 2015-10-21 | The University Of Western Australia | Antisense oligonucleotides for inducing exon skipping and methods of use thereof |
| WO2007098089A2 (en) | 2006-02-17 | 2007-08-30 | Novacea, Inc. | Treatment of hyperproliferative diseases with methotrexate n-oxide and analogs |
| CN103849629B (zh) | 2006-06-21 | 2017-06-09 | 尤尼克尔Ip股份有限公司 | 具有经修饰的用于在昆虫细胞中产生aav的aav‑rep78翻译起始密码子的载体 |
| PL2291523T3 (pl) * | 2008-06-24 | 2015-05-29 | Csl Behring Gmbh | Czynnik VIII, czynnik von Willebranda lub ich kompleksy o wydłużonym okresie półtrwania in vivo |
| BR122020021379B1 (pt) | 2008-10-24 | 2021-05-11 | Sarepta Therapeutics, Inc. | oligômero morfolino fosforodiamidato, composição que compreende o mesmo e uso do dito oligômero para tratar distrofia muscular |
| TR201816523T4 (tr) | 2009-11-12 | 2018-11-21 | Univ Western Australia | Patolojilerin tedavisine yönelik antisens moleküller ve yöntemler. |
| US9283194B2 (en) | 2010-04-16 | 2016-03-15 | The Regents Of The University Of California | Methods for protease assisted protein delivery |
| DK2699247T3 (en) * | 2011-04-20 | 2018-06-14 | Univ California | PROCEDURE FOR COMBINED CONDITIONING AND CHEMOS SELECTION IN A SIMPLE CYCLE |
| US9993440B2 (en) | 2011-09-02 | 2018-06-12 | The Regents Of The University Of California | Enzyme responsive nanocapsules for protein delivery |
| US20130085139A1 (en) | 2011-10-04 | 2013-04-04 | Royal Holloway And Bedford New College | Oligomers |
| CA2907095C (en) | 2012-03-16 | 2020-11-03 | The Regents Of The University Of California | A novel rnai molecule delivery platform based on single-sirna and shrna nanocapsules |
| HUE054260T2 (hu) | 2012-09-06 | 2021-08-30 | Univ Chicago | Antiszensz polinukleotidok exon-ugrás indukálására és eljárások disztrófiák kezelésére |
| JP6502261B2 (ja) | 2012-12-14 | 2019-04-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ターゲティング遺伝子治療のためのウイルスベクターナノカプセル、およびその調製 |
| US20140329762A1 (en) | 2013-03-15 | 2014-11-06 | Sarepta Therapeutics, Inc. | Compositions for treating muscular dystrophy |
| CN105683376A (zh) * | 2013-05-15 | 2016-06-15 | 桑格摩生物科学股份有限公司 | 用于治疗遗传病状的方法和组合物 |
| WO2015075195A1 (en) * | 2013-11-22 | 2015-05-28 | Cellectis | Method of engineering chemotherapy drug resistant t-cells for immunotherapy |
| CN107530445B (zh) | 2014-11-26 | 2021-01-05 | 加利福尼亚大学董事会 | 用于蛋白质递送的隐形纳米胶囊 |
| CN107614012A (zh) * | 2015-04-24 | 2018-01-19 | 加利福尼亚大学董事会 | 使用工程化的细胞检测、监测或治疗疾病或病况的系统及制备和使用它们的方法 |
| HK1247963A1 (zh) | 2015-05-18 | 2018-10-05 | Csl贝林基因治疗股份有限公司 | 用於hiv的治疗的基因疗法及其用途 |
| CN108495640B (zh) * | 2016-02-19 | 2022-11-04 | 加利福尼亚大学董事会 | 短发夹rna(shrna734)及其用于阳性选择和消除遗传修饰的细胞的用途 |
| EP3463428A4 (en) | 2016-05-24 | 2020-01-08 | The Regents of the University of California | GROWTH FACTOR NANO CAPSULES WITH TUNABLE RELEASE FOR BONE REGENERATION |
| CN111164211B (zh) * | 2017-07-18 | 2024-08-02 | 杰特贝林基因治疗股份有限公司 | 用于治疗β-血红蛋白病的组合物和方法 |
| JP7410856B2 (ja) * | 2017-07-18 | 2024-01-10 | シーエスエル・ベーリング・ジーン・セラピー・インコーポレイテッド | ドナー改変細胞の選択のための調節可能スイッチ |
-
2019
- 2019-12-23 KR KR1020217023088A patent/KR20210118833A/ko not_active Ceased
- 2019-12-23 JP JP2021536370A patent/JP2022514954A/ja active Pending
- 2019-12-23 AU AU2019417700A patent/AU2019417700A1/en not_active Abandoned
- 2019-12-23 WO PCT/US2019/068239 patent/WO2020139800A1/en not_active Ceased
- 2019-12-23 CA CA3123045A patent/CA3123045A1/en active Pending
- 2019-12-23 EP EP19842993.8A patent/EP3897831A1/en not_active Withdrawn
- 2019-12-23 CN CN201980092148.3A patent/CN113543848A/zh active Pending
- 2019-12-23 BR BR112021012318A patent/BR112021012318A2/pt not_active IP Right Cessation
-
2021
- 2021-06-21 US US17/353,572 patent/US20210340563A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3654994B1 (en) | A modulatable switch for selection of donor modified cells | |
| Phillips et al. | Novel therapeutic strategies for chronic hepatitis B | |
| JP2022514954A5 (https=) | ||
| EP2155225A1 (en) | Methods of treatment of skin ulcers | |
| DK2654758T3 (en) | A composition comprising at least two compounds which induce indolamine 2,3-dioxygenase (IDO) for the treatment of an autoimmune disorder or immune rejection of organs. | |
| JP2020528455A5 (https=) | ||
| JP7350871B2 (ja) | ２’３’－環状ジヌクレオチドおよびそのプロドラッグ | |
| JP2002502394A (ja) | ストレス活性化プロテインキナーゼ（ｓａｐｋ）経路の阻害及び癌療法に対する細胞の増感 | |
| CN108495640B (zh) | 短发夹rna(shrna734)及其用于阳性选择和消除遗传修饰的细胞的用途 | |
| JP7350872B2 (ja) | ３’３’－環状ジヌクレオチドおよびそのプロドラッグ | |
| Wang et al. | Engineering hematopoietic stem cells toward a functional cure of human immunodeficiency virus infection | |
| KR20020064793A (ko) | 안티센스 조성물 및 암-치료 방법 | |
| WO2023272831A1 (zh) | 水苏糖在制备用于治疗去势抵抗性前列腺癌药物中的应用 | |
| Berges et al. | Combined PI3K/Akt and Hsp90 targeting synergistically suppresses essential functions of alloreactive T cells and increases Tregs | |
| EP2665489B1 (en) | A combination comprising an adenoviral vector having a thymidine kinase gene, ganciclovir and temozolomide for use in the treatment of glioblastoma multiform | |
| JP7845648B2 (ja) | ＨＢＶ由来ｃｃｃＤＮＡの抑制剤、抑制方法、ＨＢＶ感染症用医療組成物、およびＨＢＶ感染症の治療方法 | |
| EP3420084B1 (en) | Novel approach for treating inflammatory disorders | |
| JP2023531729A5 (https=) | ||
| US20250223555A1 (en) | Reprogramming of immune-enhancing neutrophils by subclinical low-dose endotoxin for the treatment of cancer | |
| US20250144043A1 (en) | Methods of assessing cancer | |
| CN107875402B (zh) | 一种靶向基因UBE2J2的修饰siRNA的用途 | |
| Psomas et al. | Highlights from the 8th International Workshop on HIV Persistence during Therapy, 12–15 December 2017, Miami, FL, USA | |
| Watson | Characterizing a novel viral sensitizer BI-D1870 | |
| CN118995810A (zh) | 过表达atic的方法在促进心肌细胞增殖中的应用 | |
| Naldini | Luigi NALDINI |