JP2020528455A5 - - Google Patents

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Publication number
JP2020528455A5
JP2020528455A5 JP2020524723A JP2020524723A JP2020528455A5 JP 2020528455 A5 JP2020528455 A5 JP 2020528455A5 JP 2020524723 A JP2020524723 A JP 2020524723A JP 2020524723 A JP2020524723 A JP 2020524723A JP 2020528455 A5 JP2020528455 A5 JP 2020528455A5
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JP
Japan
Prior art keywords
lymphocytes
hprt
deficient
patient
population
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JP2020524723A
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English (en)
Japanese (ja)
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JP7410856B2 (ja
JP2020528455A (ja
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Priority claimed from PCT/US2018/042630 external-priority patent/WO2019018491A1/en
Publication of JP2020528455A publication Critical patent/JP2020528455A/ja
Publication of JP2020528455A5 publication Critical patent/JP2020528455A5/ja
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JP2020524723A 2017-07-18 2018-07-18 ドナー改変細胞の選択のための調節可能スイッチ Active JP7410856B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762533707P 2017-07-18 2017-07-18
US62/533,707 2017-07-18
PCT/US2018/042630 WO2019018491A1 (en) 2017-07-18 2018-07-18 MODULAR SWITCH FOR SELECTING DONOR MODIFIED CELLS

Publications (3)

Publication Number Publication Date
JP2020528455A JP2020528455A (ja) 2020-09-24
JP2020528455A5 true JP2020528455A5 (https=) 2021-08-26
JP7410856B2 JP7410856B2 (ja) 2024-01-10

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JP2020524723A Active JP7410856B2 (ja) 2017-07-18 2018-07-18 ドナー改変細胞の選択のための調節可能スイッチ

Country Status (11)

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US (3) US10426798B2 (https=)
EP (2) EP4190339B1 (https=)
JP (1) JP7410856B2 (https=)
KR (1) KR20200125574A (https=)
CN (1) CN111343996A (https=)
AU (1) AU2018304222A1 (https=)
BR (1) BR112020001132A2 (https=)
CA (1) CA3070258A1 (https=)
ES (2) ES3036762T3 (https=)
SG (1) SG11202000428PA (https=)
WO (1) WO2019018491A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
WO2015105955A1 (en) 2014-01-08 2015-07-16 Flodesign Sonics, Inc. Acoustophoresis device with dual acoustophoretic chamber
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
CN111343996A (zh) * 2017-07-18 2020-06-26 卡利门股份有限公司 用于选择供体修饰细胞的可调节开关
WO2019118921A1 (en) 2017-12-14 2019-06-20 Flodesign Sonics, Inc. Acoustic transducer drive and controller
BR112021012318A2 (pt) * 2018-12-23 2022-01-18 Csl Behring Llc Células t doadoras com interruptor de eliminação
WO2021263070A1 (en) * 2020-06-26 2021-12-30 Csl Behring Llc Donor t-cells with kill switch
US20250154457A1 (en) * 2021-03-04 2025-05-15 City Of Hope T-cells for anti-hiv car-t therapy and methods of use

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US922105A (en) 1908-10-14 1909-05-18 Axel E Anderson Hoisting apparatus.
DE69123241T2 (de) 1990-12-14 1997-04-17 Cell Genesys Inc Chimärische ketten zur transduktion von rezeptorverbundenen signalwegen
US5712149A (en) 1995-02-03 1998-01-27 Cell Genesys, Inc. Chimeric receptor molecules for delivery of co-stimulatory signals
US6103521A (en) 1995-02-06 2000-08-15 Cell Genesys, Inc. Multispecific chimeric receptors
US5965126A (en) 1996-03-25 1999-10-12 The Penn State Research Foundation use of mutant alkyltransferases for gene therapy to protect from toxicity of therapeutic alkylating agents
WO1997043900A1 (en) 1996-05-24 1997-11-27 The President And Fellows Of Harvard College In vivo selection
WO1998019540A1 (en) 1996-11-04 1998-05-14 Saint Jude Children's Research Hospital In vivo selection of primitive hematopoietic cells
US6558662B2 (en) 1997-11-14 2003-05-06 The General Hospital Corporation Treatment of hematologic disorders
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
US20030032003A1 (en) 2000-02-02 2003-02-13 Schiestl Robert H. In vivo selection
CA2428721A1 (en) 2000-11-14 2002-05-23 The General Hospital Corporation Blockade of t cell migration into epithelial gvhd target tissues
US7037900B2 (en) 2001-10-12 2006-05-02 Supergen, Inc. Composition and method for treating graft-versus-host disease
EP3101122B1 (en) * 2009-08-24 2023-06-14 Baylor College of Medicine Generation of ctl lines with specificity against multiple tumor antigens or multiple viruses
AU2012245269B2 (en) * 2011-04-20 2016-09-29 The Regents Of The University Of California Method for combined conditioning and chemoselection in a single cycle
JP6188703B2 (ja) * 2011-10-27 2017-08-30 サンガモ セラピューティクス, インコーポレイテッド Hprt遺伝子座を修飾するための方法および組成物
US20150245364A1 (en) 2012-02-16 2015-08-27 Hewlett-Packard Development Company, L.P. Radio resource management
KR102348577B1 (ko) * 2013-11-22 2022-01-06 셀렉티스 면역요법을 위한 화학요법 약물 저항성 t―세포들의 조작 방법
CA2994746A1 (en) * 2015-08-11 2017-02-16 Cellectis Cells for immunotherapy engineered for targeting cd38 antigen and for cd38 gene inactivation
WO2017126987A1 (ru) * 2016-01-18 2017-07-27 Анатолий Викторович ЗАЗУЛЯ Эритроциты для направленного транспорта лекарственного средства
US11377659B2 (en) 2016-02-19 2022-07-05 The Regents Of The University Oe California Short hairpin RNA (shRNA734) and use of same to positively select and eliminate genetically modified cells
US20180140606A1 (en) * 2016-11-18 2018-05-24 Calimmune, Inc. In Vivo Chemoselection with Low Dose Thioguanine
CN111343996A (zh) * 2017-07-18 2020-06-26 卡利门股份有限公司 用于选择供体修饰细胞的可调节开关

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