JP2022514700A - 細菌送達ビヒクルにおける使用のための分岐型受容体結合多サブユニットタンパク質複合体 - Google Patents

細菌送達ビヒクルにおける使用のための分岐型受容体結合多サブユニットタンパク質複合体 Download PDF

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JP2022514700A
JP2022514700A JP2021536201A JP2021536201A JP2022514700A JP 2022514700 A JP2022514700 A JP 2022514700A JP 2021536201 A JP2021536201 A JP 2021536201A JP 2021536201 A JP2021536201 A JP 2021536201A JP 2022514700 A JP2022514700 A JP 2022514700A
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virus
rbp
seq
terminal domain
lambda
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JPWO2020128108A5 (ko
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ヘスス・フェルナンデス-ロドリゲス
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エリゴ・バイオサイエンス
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Priority claimed from PCT/EP2019/082640 external-priority patent/WO2020109339A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • C12N2795/10322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • C12N2795/10341Use of virus, viral particle or viral elements as a vector
    • C12N2795/10342Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • C12N2795/10341Use of virus, viral particle or viral elements as a vector
    • C12N2795/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
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  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
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  • Biomedical Technology (AREA)
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  • Pharmacology & Pharmacy (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2021536201A 2018-12-21 2019-12-23 細菌送達ビヒクルにおける使用のための分岐型受容体結合多サブユニットタンパク質複合体 Pending JP2022514700A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862783258P 2018-12-21 2018-12-21
US62/783,258 2018-12-21
US201962802777P 2019-02-08 2019-02-08
US62/802,777 2019-02-08
PCT/EP2019/082640 WO2020109339A1 (en) 2018-11-27 2019-11-26 Chimeric receptor binding proteins for use in bacterial delivery vehicles
US16/696,769 US11661443B2 (en) 2018-11-27 2019-11-26 Chimeric receptor binding proteins for use in bacterial delivery vehicles
EPPCT/EP2019/082640 2019-11-26
US16/696,769 2019-11-26
PCT/EP2019/086990 WO2020128108A1 (en) 2018-12-21 2019-12-23 Branched receptor binding multi-subunit protein complexes for use in bacterial delivery vehicles

Publications (2)

Publication Number Publication Date
JP2022514700A true JP2022514700A (ja) 2022-02-14
JPWO2020128108A5 JPWO2020128108A5 (ko) 2023-01-10

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JP2021536201A Pending JP2022514700A (ja) 2018-12-21 2019-12-23 細菌送達ビヒクルにおける使用のための分岐型受容体結合多サブユニットタンパク質複合体

Country Status (7)

Country Link
EP (1) EP3898953A1 (ko)
JP (1) JP2022514700A (ko)
KR (1) KR20210107053A (ko)
CN (1) CN113498435A (ko)
CA (1) CA3120160A1 (ko)
IL (1) IL283796A (ko)
WO (1) WO2020128108A1 (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11584781B2 (en) 2019-12-30 2023-02-21 Eligo Bioscience Chimeric receptor binding proteins resistant to proteolytic degradation
TR202014396A2 (tr) * 2020-09-10 2022-03-21 Univ Yildiz Teknik Mikroorganizma hedefli, antimikrobiyal bileşen/bileşenler içeren nanoformülasyonlar.
WO2022144382A1 (en) * 2020-12-30 2022-07-07 Eligo Bioscience Chimeric receptor binding proteins resistant to proteolytic degradation
EP4342538A1 (en) * 2022-09-20 2024-03-27 Technische Universität München Simultaneous production of structural proteins from heterologous bacteriophage in cell-free expression system
US20240158760A1 (en) * 2022-11-10 2024-05-16 Laboratory Corporation Of America Holdings Synthetic phage with recombinant tail-spike proteins and related methods
CN116003531B (zh) * 2022-12-28 2023-09-05 山东省农业科学院畜牧兽医研究所 噬菌体受体结合蛋白po86在大肠杆菌o抗原血清型分型鉴定中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014124226A1 (en) 2013-02-07 2014-08-14 The Rockefeller University Sequence specific antimicrobials
EA038595B1 (ru) * 2014-12-16 2021-09-21 Си3Джей ТЕРАПЬЮТИКС, ИНК. Композиции и способы для конструирования вирусного генома in vitro

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Publication number Publication date
CN113498435A (zh) 2021-10-12
KR20210107053A (ko) 2021-08-31
WO2020128108A1 (en) 2020-06-25
EP3898953A1 (en) 2021-10-27
IL283796A (en) 2021-07-29
CA3120160A1 (en) 2020-06-25

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