CN113498435A - 用于细菌递送媒介物中的分支受体结合多亚基蛋白复合物 - Google Patents

用于细菌递送媒介物中的分支受体结合多亚基蛋白复合物 Download PDF

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CN113498435A
CN113498435A CN201980085305.8A CN201980085305A CN113498435A CN 113498435 A CN113498435 A CN 113498435A CN 201980085305 A CN201980085305 A CN 201980085305A CN 113498435 A CN113498435 A CN 113498435A
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virus
rbp
seq
terminal domain
lambda
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CN201980085305.8A
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Chinese (zh)
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J·费南德斯-罗德里格斯
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Erig Biotechnology Co ltd
Eligo Bioscience
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Erig Biotechnology Co ltd
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Priority claimed from US16/696,769 external-priority patent/US11661443B2/en
Application filed by Erig Biotechnology Co ltd filed Critical Erig Biotechnology Co ltd
Publication of CN113498435A publication Critical patent/CN113498435A/zh
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • C12N2795/10322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • C12N2795/10341Use of virus, viral particle or viral elements as a vector
    • C12N2795/10342Use of virus, viral particle or viral elements as a vector virus or viral particle as vehicle, e.g. encapsulating small organic molecule
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/10011Details dsDNA Bacteriophages
    • C12N2795/10311Siphoviridae
    • C12N2795/10341Use of virus, viral particle or viral elements as a vector
    • C12N2795/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
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  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201980085305.8A 2018-12-21 2019-12-23 用于细菌递送媒介物中的分支受体结合多亚基蛋白复合物 Pending CN113498435A (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862783258P 2018-12-21 2018-12-21
US62/783258 2018-12-21
US201962802777P 2019-02-08 2019-02-08
US62/802777 2019-02-08
EPPCT/EP2019/082640 2019-11-26
US16/696769 2019-11-26
US16/696,769 US11661443B2 (en) 2018-11-27 2019-11-26 Chimeric receptor binding proteins for use in bacterial delivery vehicles
PCT/EP2019/082640 WO2020109339A1 (en) 2018-11-27 2019-11-26 Chimeric receptor binding proteins for use in bacterial delivery vehicles
PCT/EP2019/086990 WO2020128108A1 (en) 2018-12-21 2019-12-23 Branched receptor binding multi-subunit protein complexes for use in bacterial delivery vehicles

Publications (1)

Publication Number Publication Date
CN113498435A true CN113498435A (zh) 2021-10-12

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CN201980085305.8A Pending CN113498435A (zh) 2018-12-21 2019-12-23 用于细菌递送媒介物中的分支受体结合多亚基蛋白复合物

Country Status (7)

Country Link
EP (1) EP3898953A1 (ko)
JP (1) JP2022514700A (ko)
KR (1) KR20210107053A (ko)
CN (1) CN113498435A (ko)
CA (1) CA3120160A1 (ko)
IL (1) IL283796A (ko)
WO (1) WO2020128108A1 (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116003531A (zh) * 2022-12-28 2023-04-25 山东省农业科学院畜牧兽医研究所 噬菌体受体结合蛋白po86在大肠杆菌o抗原血清型分型鉴定中的应用

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11584781B2 (en) 2019-12-30 2023-02-21 Eligo Bioscience Chimeric receptor binding proteins resistant to proteolytic degradation
TR202014396A2 (tr) * 2020-09-10 2022-03-21 Univ Yildiz Teknik Mikroorganizma hedefli, antimikrobiyal bileşen/bileşenler içeren nanoformülasyonlar.
WO2022144381A1 (en) * 2020-12-30 2022-07-07 Eligo Bioscience Microbiome modulation of a host by delivery of dna payloads with minimized spread
EP4342538A1 (en) * 2022-09-20 2024-03-27 Technische Universität München Simultaneous production of structural proteins from heterologous bacteriophage in cell-free expression system
WO2024102973A1 (en) * 2022-11-10 2024-05-16 Laboratory Corporation Of America Holdings Synthetic phage with recombinant tail-spike proteins and related methods

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016100389A1 (en) * 2014-12-16 2016-06-23 Synthetic Genomics, Inc. Compositions of and methods for in vitro viral genome engineering

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014124226A1 (en) 2013-02-07 2014-08-14 The Rockefeller University Sequence specific antimicrobials

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016100389A1 (en) * 2014-12-16 2016-06-23 Synthetic Genomics, Inc. Compositions of and methods for in vitro viral genome engineering

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DEAN SCHOLL: "Escherichia coli K1\'s capsule is a barrier to bacteriophage T7", 《APPL ENVIRON MICROBIOL 》, vol. 71, no. 8, 31 December 2005 (2005-12-31), pages 4872 - 4874, XP055664760, DOI: 10.1128/AEM.71.8.4872-4874.2005 *
HIROKI ANDO: "Engineering Modular Viral Scaffolds for Targeted Bacterial Population Editing", 《CELL SYST》, vol. 1, no. 3, 23 September 2015 (2015-09-23), pages 187 - 196, XP055450305, DOI: 10.1016/j.cels.2015.08.013 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116003531A (zh) * 2022-12-28 2023-04-25 山东省农业科学院畜牧兽医研究所 噬菌体受体结合蛋白po86在大肠杆菌o抗原血清型分型鉴定中的应用
CN116003531B (zh) * 2022-12-28 2023-09-05 山东省农业科学院畜牧兽医研究所 噬菌体受体结合蛋白po86在大肠杆菌o抗原血清型分型鉴定中的应用

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WO2020128108A1 (en) 2020-06-25
CA3120160A1 (en) 2020-06-25
KR20210107053A (ko) 2021-08-31
EP3898953A1 (en) 2021-10-27
IL283796A (en) 2021-07-29
JP2022514700A (ja) 2022-02-14

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