JP2022513888A5 - - Google Patents

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Publication number
JP2022513888A5
JP2022513888A5 JP2021534270A JP2021534270A JP2022513888A5 JP 2022513888 A5 JP2022513888 A5 JP 2022513888A5 JP 2021534270 A JP2021534270 A JP 2021534270A JP 2021534270 A JP2021534270 A JP 2021534270A JP 2022513888 A5 JP2022513888 A5 JP 2022513888A5
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JP
Japan
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JP2021534270A
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Japanese (ja)
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JP2022513888A (ja
JPWO2020123980A5 (https=
JP7557465B2 (ja
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Priority claimed from PCT/US2019/066287 external-priority patent/WO2020123980A1/en
Publication of JP2022513888A publication Critical patent/JP2022513888A/ja
Publication of JPWO2020123980A5 publication Critical patent/JPWO2020123980A5/ja
Publication of JP2022513888A5 publication Critical patent/JP2022513888A5/ja
Priority to JP2024159011A priority Critical patent/JP2024175026A/ja
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Publication of JP7557465B2 publication Critical patent/JP7557465B2/ja
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JP2021534270A 2018-12-14 2019-12-13 Il-15組成物およびその使用方法 Active JP7557465B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024159011A JP2024175026A (ja) 2018-12-14 2024-09-13 Il-15組成物およびその使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862779793P 2018-12-14 2018-12-14
US62/779,793 2018-12-14
PCT/US2019/066287 WO2020123980A1 (en) 2018-12-14 2019-12-13 Il-15 compositions and methods of use thereof

Related Child Applications (1)

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JP2024159011A Division JP2024175026A (ja) 2018-12-14 2024-09-13 Il-15組成物およびその使用方法

Publications (4)

Publication Number Publication Date
JP2022513888A JP2022513888A (ja) 2022-02-09
JPWO2020123980A5 JPWO2020123980A5 (https=) 2022-12-06
JP2022513888A5 true JP2022513888A5 (https=) 2022-12-06
JP7557465B2 JP7557465B2 (ja) 2024-09-27

Family

ID=71075819

Family Applications (2)

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JP2021534270A Active JP7557465B2 (ja) 2018-12-14 2019-12-13 Il-15組成物およびその使用方法
JP2024159011A Pending JP2024175026A (ja) 2018-12-14 2024-09-13 Il-15組成物およびその使用方法

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JP2024159011A Pending JP2024175026A (ja) 2018-12-14 2024-09-13 Il-15組成物およびその使用方法

Country Status (8)

Country Link
US (1) US20230045048A1 (https=)
EP (1) EP3893917A4 (https=)
JP (2) JP7557465B2 (https=)
KR (1) KR102911817B1 (https=)
CN (1) CN114746105A (https=)
AU (1) AU2019395266A1 (https=)
CA (1) CA3121813A1 (https=)
WO (1) WO2020123980A1 (https=)

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Publication number Priority date Publication date Assignee Title
US11629340B2 (en) 2017-03-03 2023-04-18 Obsidian Therapeutics, Inc. DHFR tunable protein regulation
CN120463822A (zh) 2018-09-27 2025-08-12 西里欧发展公司 掩蔽型细胞因子多肽
MX2022007202A (es) * 2019-12-13 2022-10-07 Cugene Inc Fármacos bioactivables a base de citocinas y metodos de uso de los mismos.
AU2021254283B2 (en) 2020-04-10 2025-12-11 Cytomx Therapeutics, Inc. Activatable cytokine constructs and related compositions and methods
WO2021257808A2 (en) * 2020-06-17 2021-12-23 Proviva Therapeutics (Hong Kong) Limited Antibodies to fibroblast activation protein and b7h3
WO2022115865A2 (en) 2020-11-25 2022-06-02 Xilio Development, Inc. Tumor-specific cleavable linkers
JP2024511387A (ja) 2021-03-16 2024-03-13 シートムエックス セラピューティクス,インコーポレイテッド マスクした活性化可能サイトカイン構成体ならびに関連する組成物及び方法
US20240228585A1 (en) * 2021-05-03 2024-07-11 President And Fellows Of Harvard College Fc-fusion protein therapeutic for the treatment of pancreatitis
EP4580683A2 (en) * 2022-08-31 2025-07-09 Proviva Therapeutics (Hong Kong) Limited Il-15 procytokine antibody fusion proteins
AU2023338694A1 (en) * 2022-09-08 2025-04-03 Cugene Inc. Novel pd1-targeted il-15 immunocytokine and vitokine fusions
WO2024216170A2 (en) * 2023-04-12 2024-10-17 Cytomx Therapeutics, Inc. Activatable cytokine constructs and related compositions and methods
WO2025085744A1 (en) * 2023-10-18 2025-04-24 Memorial Sloan-Kettering Cancer Center Fusion polypeptides and uses thereof
WO2025180355A1 (zh) * 2024-02-27 2025-09-04 江苏奥赛康生物医药有限公司 Il-15前药与免疫检查点抑制剂的组合

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9912350D0 (en) * 1999-05-26 1999-07-28 European Molecular Biology Lab Embl Modified cytokine
FI117667B (fi) * 2001-07-05 2007-01-15 Univ Zuerich Farmaseuttinen koostumus, joka soveltuu käytettäväksi ortopediassa ja hammaslääketieteessä
ES2327830T3 (es) * 2002-03-29 2009-11-04 Schering Corporation Anticuerpos monoclonales humanos anti-interleuquina-5 y metodos y composiciones que los contienen.
US20110178279A1 (en) * 2009-08-03 2011-07-21 Williams John C Development of masked therapeutic antibodies to limit off-target effects: application to anti-egfr antibodies
US20100189651A1 (en) * 2009-01-12 2010-07-29 Cytomx Therapeutics, Llc Modified antibody compositions, methods of making and using thereof
JP5861223B2 (ja) * 2009-02-23 2016-02-16 サイトムエックス セラピューティクス, インク.CytomX Therapeutics, Inc. プロタンパク質およびその使用方法
GB201203442D0 (en) * 2012-02-28 2012-04-11 Univ Birmingham Immunotherapeutic molecules and uses
WO2016004383A1 (en) * 2014-07-03 2016-01-07 City Of Hope Tumor-selective ctla-4 antagonists
WO2016210447A1 (en) * 2015-06-26 2016-12-29 University Of Southern California Masking chimeric antigen receptor t cells for tumor-specific activation
WO2017201352A1 (en) * 2016-05-18 2017-11-23 Modernatx, Inc. Mrna combination therapy for the treatment of cancer
CN110214147A (zh) * 2016-10-14 2019-09-06 Xencor股份有限公司 IL15/IL15Rα异源二聚体FC-融合蛋白
KR20190102259A (ko) * 2017-01-10 2019-09-03 인트렉손 코포레이션 신규의 유전자 스위치 발현 시스템을 통한 폴리펩티드의 발현 조절

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