JP2022513347A - 高度にコンパクトな多入力論理ゲートをコードする核酸ベクターを使用して疾患を処置する方法 - Google Patents
高度にコンパクトな多入力論理ゲートをコードする核酸ベクターを使用して疾患を処置する方法 Download PDFInfo
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- JP2022513347A JP2022513347A JP2021544949A JP2021544949A JP2022513347A JP 2022513347 A JP2022513347 A JP 2022513347A JP 2021544949 A JP2021544949 A JP 2021544949A JP 2021544949 A JP2021544949 A JP 2021544949A JP 2022513347 A JP2022513347 A JP 2022513347A
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/007—Vector systems having a special element relevant for transcription cell cycle specific enhancer/promoter combination
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/20—Vector systems having a special element relevant for transcription transcription of more than one cistron
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/30—Vector systems having a special element relevant for transcription being an enhancer not forming part of the promoter region
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/40—Vector systems having a special element relevant for transcription being an insulator
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- Wood Science & Technology (AREA)
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- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Microbiology (AREA)
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- Molecular Biology (AREA)
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- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024192576A JP2025049296A (ja) | 2018-10-11 | 2024-11-01 | 高度にコンパクトな多入力論理ゲートをコードする核酸ベクターを使用して疾患を処置する方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862744173P | 2018-10-11 | 2018-10-11 | |
| US62/744,173 | 2018-10-11 | ||
| PCT/IB2019/001100 WO2020074956A2 (en) | 2018-10-11 | 2019-10-10 | A method to treat disease using a nucleic acid vector encoding a highly compact multi-input logic gate |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024192576A Division JP2025049296A (ja) | 2018-10-11 | 2024-11-01 | 高度にコンパクトな多入力論理ゲートをコードする核酸ベクターを使用して疾患を処置する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022513347A true JP2022513347A (ja) | 2022-02-07 |
| JP2022513347A5 JP2022513347A5 (https=) | 2022-10-14 |
Family
ID=68654816
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021544949A Pending JP2022513347A (ja) | 2018-10-11 | 2019-10-10 | 高度にコンパクトな多入力論理ゲートをコードする核酸ベクターを使用して疾患を処置する方法 |
| JP2024192576A Pending JP2025049296A (ja) | 2018-10-11 | 2024-11-01 | 高度にコンパクトな多入力論理ゲートをコードする核酸ベクターを使用して疾患を処置する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024192576A Pending JP2025049296A (ja) | 2018-10-11 | 2024-11-01 | 高度にコンパクトな多入力論理ゲートをコードする核酸ベクターを使用して疾患を処置する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20210381001A1 (https=) |
| EP (1) | EP3864158A2 (https=) |
| JP (2) | JP2022513347A (https=) |
| KR (1) | KR20210075126A (https=) |
| CN (1) | CN112823209A (https=) |
| AU (2) | AU2019359505B2 (https=) |
| CA (1) | CA3113325A1 (https=) |
| WO (1) | WO2020074956A2 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2021256845A1 (en) * | 2020-04-14 | 2022-11-24 | Eidgenössische Technische Hochschule Zürich | Cell classifier circuits and methods of use thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008545406A (ja) * | 2005-05-27 | 2008-12-18 | フォンダツィオーネ セントロ サン ラファエレ デル モンテ タボール | 遺伝子ベクター |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003216207A1 (en) | 2002-02-08 | 2003-09-02 | The Regents Of The University Of California | A transcription amplification system for molecular imaging |
| WO2008070448A2 (en) | 2006-11-22 | 2008-06-12 | Board Of Regents, The University Of Texas System | Cancer-specific promoters |
| WO2012012739A2 (en) | 2010-07-22 | 2012-01-26 | President And Fellows Of Harvard College | Multiple input biologic classifier circuits for cells |
| CN105144204B (zh) | 2012-12-13 | 2018-02-27 | 麻省理工学院 | 基于重组酶的逻辑与存储系统 |
| JP6712948B2 (ja) * | 2013-12-12 | 2020-06-24 | ザ・ブロード・インスティテュート・インコーポレイテッド | 組成物、及びヌクレオチドリピート障害におけるcrispr−cas系の使用方法 |
| WO2015188191A1 (en) | 2014-06-06 | 2015-12-10 | Wong Wilson W | Dna recombinase circuits for logical control of gene expression |
| JP6936952B2 (ja) * | 2015-10-16 | 2021-09-22 | アストラゼネカ アクチボラグ | 細胞ゲノムの誘導性改変 |
-
2019
- 2019-10-10 CA CA3113325A patent/CA3113325A1/en active Pending
- 2019-10-10 CN CN201980066858.9A patent/CN112823209A/zh active Pending
- 2019-10-10 AU AU2019359505A patent/AU2019359505B2/en active Active
- 2019-10-10 WO PCT/IB2019/001100 patent/WO2020074956A2/en not_active Ceased
- 2019-10-10 US US17/283,598 patent/US20210381001A1/en active Pending
- 2019-10-10 KR KR1020217013645A patent/KR20210075126A/ko active Pending
- 2019-10-10 JP JP2021544949A patent/JP2022513347A/ja active Pending
- 2019-10-10 EP EP19808879.1A patent/EP3864158A2/en active Pending
-
2024
- 2024-11-01 JP JP2024192576A patent/JP2025049296A/ja active Pending
-
2026
- 2026-03-05 AU AU2026201687A patent/AU2026201687A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008545406A (ja) * | 2005-05-27 | 2008-12-18 | フォンダツィオーネ セントロ サン ラファエレ デル モンテ タボール | 遺伝子ベクター |
Non-Patent Citations (5)
| Title |
|---|
| "Bartolomeo A., Design and Implementation of Transcription Factor Based Gene Classifier Circuits, [on", DOCTORAL THESIS, ETH ZURICH, vol. pp. 1-172, JPN6023039942, 2017, ISSN: 0005515876 * |
| BMC BIOTECHNOL, vol. 13, JPN6023039938, 22 January 2013 (2013-01-22), pages 5 - 1, ISSN: 0005515878 * |
| CELL REP, vol. 16, no. 9, JPN6023039936, 18 August 2016 (2016-08-18), pages 2525 - 2537, ISSN: 0005515877 * |
| MOL THER, vol. 15, no. 7, JPN6023039940, 1 May 2007 (2007-05-01), pages 1340 - 2347, ISSN: 0005515880 * |
| NUCLEIC ACIDS RES, vol. 46, no. 18, JPN7023003645, 7 September 2018 (2018-09-07), pages 9855 - 9863, ISSN: 0005515879 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2019359505B2 (en) | 2026-03-19 |
| AU2019359505A1 (en) | 2021-04-29 |
| US20210381001A1 (en) | 2021-12-09 |
| CA3113325A1 (en) | 2020-04-16 |
| AU2026201687A1 (en) | 2026-03-26 |
| WO2020074956A2 (en) | 2020-04-16 |
| JP2025049296A (ja) | 2025-04-03 |
| EP3864158A2 (en) | 2021-08-18 |
| KR20210075126A (ko) | 2021-06-22 |
| WO2020074956A3 (en) | 2020-05-22 |
| CN112823209A (zh) | 2021-05-18 |
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