KR20210075126A - 고도로 콤팩트한 다중-입력 논리 게이트를 코딩하는 핵산 벡터를 사용하여 질환을 치료하는 방법 - Google Patents
고도로 콤팩트한 다중-입력 논리 게이트를 코딩하는 핵산 벡터를 사용하여 질환을 치료하는 방법 Download PDFInfo
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- KR20210075126A KR20210075126A KR1020217013645A KR20217013645A KR20210075126A KR 20210075126 A KR20210075126 A KR 20210075126A KR 1020217013645 A KR1020217013645 A KR 1020217013645A KR 20217013645 A KR20217013645 A KR 20217013645A KR 20210075126 A KR20210075126 A KR 20210075126A
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/007—Vector systems having a special element relevant for transcription cell cycle specific enhancer/promoter combination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/20—Vector systems having a special element relevant for transcription transcription of more than one cistron
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/30—Vector systems having a special element relevant for transcription being an enhancer not forming part of the promoter region
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/40—Vector systems having a special element relevant for transcription being an insulator
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- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862744173P | 2018-10-11 | 2018-10-11 | |
| US62/744,173 | 2018-10-11 | ||
| PCT/IB2019/001100 WO2020074956A2 (en) | 2018-10-11 | 2019-10-10 | A method to treat disease using a nucleic acid vector encoding a highly compact multi-input logic gate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20210075126A true KR20210075126A (ko) | 2021-06-22 |
Family
ID=68654816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217013645A Pending KR20210075126A (ko) | 2018-10-11 | 2019-10-10 | 고도로 콤팩트한 다중-입력 논리 게이트를 코딩하는 핵산 벡터를 사용하여 질환을 치료하는 방법 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20210381001A1 (https=) |
| EP (1) | EP3864158A2 (https=) |
| JP (2) | JP2022513347A (https=) |
| KR (1) | KR20210075126A (https=) |
| CN (1) | CN112823209A (https=) |
| AU (2) | AU2019359505B2 (https=) |
| CA (1) | CA3113325A1 (https=) |
| WO (1) | WO2020074956A2 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2021256845A1 (en) * | 2020-04-14 | 2022-11-24 | Eidgenössische Technische Hochschule Zürich | Cell classifier circuits and methods of use thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003216207A1 (en) | 2002-02-08 | 2003-09-02 | The Regents Of The University Of California | A transcription amplification system for molecular imaging |
| CA2609142C (en) | 2005-05-27 | 2016-02-09 | Fondazione Centro San Raffaele Del Monte Tabor | Therapeutic gene vectors comprising mirna target sequences |
| WO2008070448A2 (en) | 2006-11-22 | 2008-06-12 | Board Of Regents, The University Of Texas System | Cancer-specific promoters |
| WO2012012739A2 (en) | 2010-07-22 | 2012-01-26 | President And Fellows Of Harvard College | Multiple input biologic classifier circuits for cells |
| CN105144204B (zh) | 2012-12-13 | 2018-02-27 | 麻省理工学院 | 基于重组酶的逻辑与存储系统 |
| JP6712948B2 (ja) * | 2013-12-12 | 2020-06-24 | ザ・ブロード・インスティテュート・インコーポレイテッド | 組成物、及びヌクレオチドリピート障害におけるcrispr−cas系の使用方法 |
| WO2015188191A1 (en) | 2014-06-06 | 2015-12-10 | Wong Wilson W | Dna recombinase circuits for logical control of gene expression |
| JP6936952B2 (ja) * | 2015-10-16 | 2021-09-22 | アストラゼネカ アクチボラグ | 細胞ゲノムの誘導性改変 |
-
2019
- 2019-10-10 CA CA3113325A patent/CA3113325A1/en active Pending
- 2019-10-10 CN CN201980066858.9A patent/CN112823209A/zh active Pending
- 2019-10-10 AU AU2019359505A patent/AU2019359505B2/en active Active
- 2019-10-10 WO PCT/IB2019/001100 patent/WO2020074956A2/en not_active Ceased
- 2019-10-10 US US17/283,598 patent/US20210381001A1/en active Pending
- 2019-10-10 KR KR1020217013645A patent/KR20210075126A/ko active Pending
- 2019-10-10 JP JP2021544949A patent/JP2022513347A/ja active Pending
- 2019-10-10 EP EP19808879.1A patent/EP3864158A2/en active Pending
-
2024
- 2024-11-01 JP JP2024192576A patent/JP2025049296A/ja active Pending
-
2026
- 2026-03-05 AU AU2026201687A patent/AU2026201687A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2019359505B2 (en) | 2026-03-19 |
| AU2019359505A1 (en) | 2021-04-29 |
| JP2022513347A (ja) | 2022-02-07 |
| US20210381001A1 (en) | 2021-12-09 |
| CA3113325A1 (en) | 2020-04-16 |
| AU2026201687A1 (en) | 2026-03-26 |
| WO2020074956A2 (en) | 2020-04-16 |
| JP2025049296A (ja) | 2025-04-03 |
| EP3864158A2 (en) | 2021-08-18 |
| WO2020074956A3 (en) | 2020-05-22 |
| CN112823209A (zh) | 2021-05-18 |
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