JP2022513116A5 - - Google Patents

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Publication number
JP2022513116A5
JP2022513116A5 JP2021529003A JP2021529003A JP2022513116A5 JP 2022513116 A5 JP2022513116 A5 JP 2022513116A5 JP 2021529003 A JP2021529003 A JP 2021529003A JP 2021529003 A JP2021529003 A JP 2021529003A JP 2022513116 A5 JP2022513116 A5 JP 2022513116A5
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JP
Japan
Prior art keywords
cells
express
car
artificial
ligand
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JP2021529003A
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English (en)
Japanese (ja)
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JP7450892B2 (ja
JP2022513116A (ja
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Priority claimed from EP18208092.9A external-priority patent/EP3656851A1/en
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Publication of JP2022513116A5 publication Critical patent/JP2022513116A5/ja
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Publication of JP7450892B2 publication Critical patent/JP7450892B2/ja
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JP2021529003A 2018-11-23 2019-11-22 Ｎｋ細胞のための人工ｈｌａ陽性フィーダー細胞株及びその使用 Active JP7450892B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18208092.9A EP3656851A1 (en) 2018-11-23 2018-11-23 Artificial hla-positive feeder cell lines for nk cells and uses thereof
EP18208092.9 2018-11-23
PCT/EP2019/082283 WO2020104676A1 (en) 2018-11-23 2019-11-22 Artificial hla-positive feeder cell lines for nk cells and uses thereof

Publications (3)

Publication Number Publication Date
JP2022513116A JP2022513116A (ja) 2022-02-07
JP2022513116A5 true JP2022513116A5 (https=) 2022-09-30
JP7450892B2 JP7450892B2 (ja) 2024-03-18

Family

ID=64664021

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021529003A Active JP7450892B2 (ja) 2018-11-23 2019-11-22 Ｎｋ細胞のための人工ｈｌａ陽性フィーダー細胞株及びその使用

Country Status (5)

Country Link
US (1) US11578307B2 (https=)
EP (2) EP3656851A1 (https=)
JP (1) JP7450892B2 (https=)
CA (1) CA3119403C (https=)
WO (1) WO2020104676A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7118055B2 (ja) * 2016-09-29 2022-08-15 イプセン バイオファーム リミテッド ハイブリッド神経毒
IL276365B2 (en) 2018-02-01 2023-10-01 Nkmax Co Ltd A method for the production of natural killer cells and a preparation for cancer treatment
US20220387493A1 (en) * 2019-11-06 2022-12-08 Baylor College Of Medicine Method for producing cytotoxic effector memory t-cells for car t-cell treatment of cancer
EP4163366A4 (en) * 2020-06-09 2024-08-21 Samsung Life Public Welfare Foundation GENETICALLY MODIFIED CELL LINE FOR ACTIVATION AND AMPLIFICATION OF NK CELLS AND USE THEREOF
CN112048482A (zh) * 2020-09-09 2020-12-08 广东昭泰体内生物医药科技有限公司 一种nk样细胞的培养方法
US12264184B2 (en) * 2021-02-23 2025-04-01 H. Lee Moffitt Cancer Center And Research Institute, Inc. DAP12 constructs and their use to enhance DC vaccines and immunotherapies
TW202338085A (zh) * 2021-11-18 2023-10-01 美商健生生物科技公司 用於擴增自然殺手細胞製劑之無餵養細胞培養方法
WO2023096352A1 (ko) * 2021-11-25 2023-06-01 사회복지법인 삼성생명공익재단 Hla-e를 발현하도록 유전적으로 조작된 배양보조세포주, 및 그의 용도
CN117343906A (zh) * 2022-07-04 2024-01-05 上海优卡迪生物医药科技有限公司 表达重组抗原蛋白的饲养细胞及其制备方法和应用
CN115725509B (zh) * 2022-12-09 2025-07-04 上海贝斯昂科生物科技有限公司 一种基因工程细胞的制备及其在nk细胞体外扩增中的应用
KR102669705B1 (ko) * 2023-02-24 2024-06-10 이엔셀 주식회사 제대혈 유래 자연 살해 세포의 확장배양방법
CN116286666B (zh) * 2023-05-15 2023-08-04 成都云测医学生物技术有限公司 滋养层细胞及其制备方法、应用和扩增nk细胞的方法
CN121889169A (zh) * 2023-09-25 2026-04-17 南京传奇生物科技有限公司 经修饰的免疫细胞和钙调磷酸酶抑制剂及其用途
GB202317912D0 (en) * 2023-11-23 2024-01-10 Univ College Cardiff Consultants Ltd Viral-based immuno therapeutic
WO2025220989A1 (ko) * 2024-04-16 2025-10-23 주식회사 유씨아이테라퓨틱스 자연살해세포의 증폭 및 형질 도입 효율 증진용 피더 세포

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4353888A (en) 1980-12-23 1982-10-12 Sefton Michael V Encapsulation of live animal cells
US4744933A (en) 1984-02-15 1988-05-17 Massachusetts Institute Of Technology Process for encapsulation and encapsulated active material system
US4749620A (en) 1984-02-15 1988-06-07 Massachusetts Institute Of Technology Encapsulated active material system
JPH0628570B2 (ja) 1986-02-13 1994-04-20 雪印乳業株式会社 カプセル体の製造方法及び装置
EP0301777A1 (en) 1987-07-28 1989-02-01 Queen's University At Kingston Multiple membrane microencapsulation
US5089272A (en) 1989-03-29 1992-02-18 Snow Brand Milk Products Co., Ltd. Process for producing capsules having a permeability-controllable membrane
US5084350A (en) 1990-02-16 1992-01-28 The Royal Institution For The Advance Of Learning (Mcgill University) Method for encapsulating biologically active material including cells
US5578442A (en) 1992-03-23 1996-11-26 Vivorx, Inc. Graft copolymers of polycationic species and water-soluble polymers, and use therefor
SG48813A1 (en) 1993-08-12 1998-05-18 Cytotherapeutics Inc Improved composition and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
WO2012131419A1 (en) 2011-03-25 2012-10-04 Txcell Method for using regulatory t cells in therapy
EP2702145A1 (en) * 2011-04-28 2014-03-05 Institut National de la Sante et de la Recherche Medicale (INSERM) Methods for preparing accessory cells and uses thereof for preparing activated nk cells
WO2014037422A1 (en) 2012-09-04 2014-03-13 Inven2 As Selective and controlled expansion of educated nk cells
WO2015010096A1 (en) 2013-07-18 2015-01-22 Baylor College Of Medicine Method of enhancing potency of immune cells
HK1245080A1 (zh) * 2014-10-27 2018-08-24 University Of Central Florida Research Foundation, Inc. 自然杀伤细胞的方法和组合物
GB201616237D0 (en) * 2016-09-23 2016-11-09 Univ Oslo Hf Modulation of function of immune effector cells

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