JP2022513116A5 - - Google Patents
Info
- Publication number
- JP2022513116A5 JP2022513116A5 JP2021529003A JP2021529003A JP2022513116A5 JP 2022513116 A5 JP2022513116 A5 JP 2022513116A5 JP 2021529003 A JP2021529003 A JP 2021529003A JP 2021529003 A JP2021529003 A JP 2021529003A JP 2022513116 A5 JP2022513116 A5 JP 2022513116A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- express
- car
- artificial
- ligand
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18208092.9A EP3656851A1 (en) | 2018-11-23 | 2018-11-23 | Artificial hla-positive feeder cell lines for nk cells and uses thereof |
| EP18208092.9 | 2018-11-23 | ||
| PCT/EP2019/082283 WO2020104676A1 (en) | 2018-11-23 | 2019-11-22 | Artificial hla-positive feeder cell lines for nk cells and uses thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022513116A JP2022513116A (ja) | 2022-02-07 |
| JP2022513116A5 true JP2022513116A5 (https=) | 2022-09-30 |
| JPWO2020104676A5 JPWO2020104676A5 (https=) | 2022-09-30 |
| JP7450892B2 JP7450892B2 (ja) | 2024-03-18 |
Family
ID=64664021
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021529003A Active JP7450892B2 (ja) | 2018-11-23 | 2019-11-22 | Nk細胞のための人工hla陽性フィーダー細胞株及びその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11578307B2 (https=) |
| EP (2) | EP3656851A1 (https=) |
| JP (1) | JP7450892B2 (https=) |
| CA (1) | CA3119403C (https=) |
| WO (1) | WO2020104676A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018060351A1 (en) * | 2016-09-29 | 2018-04-05 | Ipsen Biopharm Limited | Hybrid neurotoxins |
| EP3746095A4 (en) | 2018-02-01 | 2021-04-21 | Nkmax Co., Ltd. | Method of producing natural killer cells and composition for treating cancer |
| KR20220095228A (ko) * | 2019-11-06 | 2022-07-06 | 베이롤 칼리지 오브 메드신 | 암의 t 세포 치료를 위한 세포독성 효과기 기억 t 세포를 생산하는 방법 |
| EP4163366A4 (en) * | 2020-06-09 | 2024-08-21 | Samsung Life Public Welfare Foundation | GENETICALLY MODIFIED CELL LINE FOR ACTIVATION AND AMPLIFICATION OF NK CELLS AND USE THEREOF |
| CN112048482A (zh) * | 2020-09-09 | 2020-12-08 | 广东昭泰体内生物医药科技有限公司 | 一种nk样细胞的培养方法 |
| US12264184B2 (en) * | 2021-02-23 | 2025-04-01 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | DAP12 constructs and their use to enhance DC vaccines and immunotherapies |
| US20230149464A1 (en) * | 2021-11-18 | 2023-05-18 | Janssen Biotech, Inc. | Feeder free cell culture methods for expanding natural killer cell preparations |
| WO2023096352A1 (ko) * | 2021-11-25 | 2023-06-01 | 사회복지법인 삼성생명공익재단 | Hla-e를 발현하도록 유전적으로 조작된 배양보조세포주, 및 그의 용도 |
| CN117343906A (zh) * | 2022-07-04 | 2024-01-05 | 上海优卡迪生物医药科技有限公司 | 表达重组抗原蛋白的饲养细胞及其制备方法和应用 |
| CN115725509B (zh) * | 2022-12-09 | 2025-07-04 | 上海贝斯昂科生物科技有限公司 | 一种基因工程细胞的制备及其在nk细胞体外扩增中的应用 |
| KR102669705B1 (ko) * | 2023-02-24 | 2024-06-10 | 이엔셀 주식회사 | 제대혈 유래 자연 살해 세포의 확장배양방법 |
| CN116286666B (zh) * | 2023-05-15 | 2023-08-04 | 成都云测医学生物技术有限公司 | 滋养层细胞及其制备方法、应用和扩增nk细胞的方法 |
| AU2024351310A1 (en) * | 2023-09-25 | 2026-03-26 | Legend Biotech Ireland Limited | Modified immune cells and calcineurin inhibitors and uses thereof |
| GB202317912D0 (en) * | 2023-11-23 | 2024-01-10 | Univ College Cardiff Consultants Ltd | Viral-based immuno therapeutic |
| KR20250153112A (ko) * | 2024-04-16 | 2025-10-24 | 주식회사 유씨아이테라퓨틱스 | 자연살해세포의 증폭 및 형질 도입 효율 증진용 피더 세포 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4353888A (en) | 1980-12-23 | 1982-10-12 | Sefton Michael V | Encapsulation of live animal cells |
| US4749620A (en) | 1984-02-15 | 1988-06-07 | Massachusetts Institute Of Technology | Encapsulated active material system |
| US4744933A (en) | 1984-02-15 | 1988-05-17 | Massachusetts Institute Of Technology | Process for encapsulation and encapsulated active material system |
| JPH0628570B2 (ja) | 1986-02-13 | 1994-04-20 | 雪印乳業株式会社 | カプセル体の製造方法及び装置 |
| EP0301777A1 (en) | 1987-07-28 | 1989-02-01 | Queen's University At Kingston | Multiple membrane microencapsulation |
| US5089272A (en) | 1989-03-29 | 1992-02-18 | Snow Brand Milk Products Co., Ltd. | Process for producing capsules having a permeability-controllable membrane |
| US5084350A (en) | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
| US5578442A (en) | 1992-03-23 | 1996-11-26 | Vivorx, Inc. | Graft copolymers of polycationic species and water-soluble polymers, and use therefor |
| ATE218893T1 (de) | 1993-08-12 | 2002-06-15 | Neurotech Sa | Biokompatible immunoisolatorische kapseln, die genetisch veränderte zellen enthalten |
| WO2012131419A1 (en) * | 2011-03-25 | 2012-10-04 | Txcell | Method for using regulatory t cells in therapy |
| WO2012146702A1 (en) * | 2011-04-28 | 2012-11-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for preparing accessory cells and uses thereof for preparing activated nk cells |
| EP2893003B1 (en) * | 2012-09-04 | 2021-03-31 | Inven2 AS | Selective and controlled expansion of educated nk cells |
| EP3021853A1 (en) * | 2013-07-18 | 2016-05-25 | Baylor College Of Medicine | Method of enhancing potency of immune cells |
| EP3223856B1 (en) * | 2014-10-27 | 2025-09-24 | University of Central Florida Research Foundation, Inc. | Methods and compositions for natural killer cells |
| GB201616237D0 (en) * | 2016-09-23 | 2016-11-09 | Univ Oslo Hf | Modulation of function of immune effector cells |
-
2018
- 2018-11-23 EP EP18208092.9A patent/EP3656851A1/en not_active Withdrawn
-
2019
- 2019-11-22 WO PCT/EP2019/082283 patent/WO2020104676A1/en not_active Ceased
- 2019-11-22 CA CA3119403A patent/CA3119403C/en active Active
- 2019-11-22 JP JP2021529003A patent/JP7450892B2/ja active Active
- 2019-11-22 US US17/293,895 patent/US11578307B2/en active Active
- 2019-11-22 EP EP19806246.5A patent/EP3884040A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022513116A5 (https=) | ||
| US20220296690A1 (en) | Engineered t cells and uses therefor | |
| JP7781243B2 (ja) | ガイダンス及びナビゲーションコントロール蛋白質並びにその生産及び使用方法 | |
| KR102879284B1 (ko) | 항-메소텔린 키메라 항원 수용체(car) 작제물 및 이의 용도 | |
| US12304935B2 (en) | Immunomodulatory polypeptides and related compositions and methods | |
| CN108884164B (zh) | 用于免疫疗法的经修饰细胞 | |
| JP2022109953A (ja) | 細胞免疫療法のための方法および組成物 | |
| US11725053B2 (en) | Chimeric antigen receptors comprising a human transferrin epitope sequence | |
| CN109651511B (zh) | 一种靶向bcma的嵌合抗原受体及其应用 | |
| CN107523545A (zh) | 一种高效稳定表达抗体的杀伤性细胞及其用途 | |
| CN112955469B (zh) | 新型拮抗性抗tnfr2抗体分子 | |
| US10023648B2 (en) | Anti-TOSO chimeric antigen receptor and its use | |
| JPWO2020104676A5 (https=) | ||
| CN113784980A (zh) | 人源化抗Claudin18.2嵌合抗原受体及其用途 | |
| CN112442126A (zh) | 一种抗人cs1抗原的单克隆抗体及其car-t细胞 | |
| TWI896517B (zh) | 雙專一性抗體及製造與使用其的方法 | |
| TW202405177A (zh) | 治療自體免疫性疾病之方法及組合物 | |
| KR20210115435A (ko) | 항-bcma 결합 영역, 이를 포함하는 융합단백질, 및 이를 포함하는 조성물 | |
| US20190287013A1 (en) | Methods for determining dosing of a therapeutic agent and related treatments | |
| Battin et al. | Engineered soluble, trimerized 4-1BBL variants as potent immunomodulatory agents | |
| WO2025148750A1 (zh) | 膜表达il-10及其用途 | |
| JPWO2022235662A5 (https=) | ||
| US20250121007A1 (en) | Compositions for the treatment of cancer | |
| CN120529915A (zh) | 嵌合抗原受体和抗体-nkg2d配体结构域融合蛋白 | |
| HK40041676A (en) | Anti-mesothelin chimeric antigen receptor (car) constructs and uses thereof |