JP2023527621A5 - - Google Patents

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Publication number
JP2023527621A5
JP2023527621A5 JP2022555742A JP2022555742A JP2023527621A5 JP 2023527621 A5 JP2023527621 A5 JP 2023527621A5 JP 2022555742 A JP2022555742 A JP 2022555742A JP 2022555742 A JP2022555742 A JP 2022555742A JP 2023527621 A5 JP2023527621 A5 JP 2023527621A5
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JP
Japan
Prior art keywords
tag
domain
chimeric antigen
receptor
antigen receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022555742A
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English (en)
Japanese (ja)
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JP2023527621A (ja
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Publication date
Priority claimed from EP20163257.7A external-priority patent/EP3881866A1/en
Application filed filed Critical
Publication of JP2023527621A publication Critical patent/JP2023527621A/ja
Publication of JP2023527621A5 publication Critical patent/JP2023527621A5/ja
Pending legal-status Critical Current

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JP2022555742A 2020-03-16 2021-03-16 哺乳類におけるキメラ抗原受容体媒介性免疫応答を刺激するための方法における使用のための、pd-l1および/またはpd-l2を含む標的化モジュール Pending JP2023527621A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20163257.7 2020-03-16
EP20163257.7A EP3881866A1 (en) 2020-03-16 2020-03-16 A targeting module comprising pd-l1 and/or pd-l2 for use in a method for stimulating a chimeric antigen receptor mediated response in a mammal
PCT/EP2021/056625 WO2021185807A1 (en) 2020-03-16 2021-03-16 A targeting module comprising pd-l1 and/or pd-l2 for use in a method for stimulating a chimeric antigen receptor mediated immune response in a mammal

Publications (2)

Publication Number Publication Date
JP2023527621A JP2023527621A (ja) 2023-06-30
JP2023527621A5 true JP2023527621A5 (https=) 2024-07-03

Family

ID=69844641

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022555742A Pending JP2023527621A (ja) 2020-03-16 2021-03-16 哺乳類におけるキメラ抗原受容体媒介性免疫応答を刺激するための方法における使用のための、pd-l1および/またはpd-l2を含む標的化モジュール

Country Status (7)

Country Link
US (1) US20230183351A1 (https=)
EP (2) EP3881866A1 (https=)
JP (1) JP2023527621A (https=)
CN (1) CN115279407A (https=)
AU (1) AU2021237694A1 (https=)
CA (1) CA3170250A1 (https=)
WO (1) WO2021185807A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021234006A1 (en) * 2020-05-20 2021-11-25 Miltenyi Biotec B.V. & Co. KG Compositions and methods for treating cancer expressing cd90 and cd326
WO2025219955A1 (en) * 2024-04-17 2025-10-23 BioNTech SE Soluble tcrs and methods of use thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3255060A1 (en) * 2008-12-09 2017-12-13 F. Hoffmann-La Roche AG Anti-pd-l1 antibodies and their use to enhance t-cell function
US9233125B2 (en) 2010-12-14 2016-01-12 University Of Maryland, Baltimore Universal anti-tag chimeric antigen receptor-expressing T cells and methods of treating cancer
WO2013044225A1 (en) 2011-09-22 2013-03-28 The Trustees Of The University Of Pennsylvania A universal immune receptor expressed by t cells for the targeting of diverse and multiple antigens
CN105829349B (zh) * 2013-10-15 2023-02-03 斯克利普斯研究所 肽嵌合抗原受体t细胞开关和其用途
EP2990416B1 (en) 2014-08-29 2018-06-20 GEMoaB Monoclonals GmbH Universal chimeric antigen receptor expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders
US11091546B2 (en) * 2015-04-15 2021-08-17 The Scripps Research Institute Optimized PNE-based chimeric receptor T cell switches and uses thereof
EP3315511A1 (en) * 2016-10-29 2018-05-02 Miltenyi Biotec GmbH Adapter chimeric antigen receptor expressing cells for targeting of multiple antigens
DK3592769T3 (da) * 2017-03-09 2024-08-12 Genmab As Antistoffer mod pd-l1
WO2018224660A1 (en) * 2017-06-09 2018-12-13 Armin Ehninger Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders

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