JP2022512994A - Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 - Google Patents

Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 Download PDF

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JP2022512994A
JP2022512994A JP2021525298A JP2021525298A JP2022512994A JP 2022512994 A JP2022512994 A JP 2022512994A JP 2021525298 A JP2021525298 A JP 2021525298A JP 2021525298 A JP2021525298 A JP 2021525298A JP 2022512994 A JP2022512994 A JP 2022512994A
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cells
car
promoter
sequence identity
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JP2022512994A5 (https=
JPWO2020102589A5 (https=
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イスマイール，リサール
リー，ユンチン
ロビンソン，マレー
タン，イン，シム
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メディシックス セラピューティクス ピーティーイー リミテッド
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Publication of JP2022512994A5 publication Critical patent/JP2022512994A5/ja
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    • A61K40/31—Chimeric antigen receptors [CAR]
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JP2021525298A 2018-11-14 2019-11-14 Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 Pending JP2022512994A (ja)

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JP2025001976A JP2025072367A (ja) 2018-11-14 2025-01-06 Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用

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US201862767069P 2018-11-14 2018-11-14
US62/767,069 2018-11-14
PCT/US2019/061549 WO2020102589A1 (en) 2018-11-14 2019-11-14 Two-gene vectors for generating car-t cells and uses thereof

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JP2022512994A true JP2022512994A (ja) 2022-02-07
JP2022512994A5 JP2022512994A5 (https=) 2022-11-22
JPWO2020102589A5 JPWO2020102589A5 (https=) 2022-11-22

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JP2025001976A Pending JP2025072367A (ja) 2018-11-14 2025-01-06 Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用

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US (1) US20210395779A1 (https=)
EP (1) EP3864052A4 (https=)
JP (2) JP2022512994A (https=)
KR (1) KR20210091250A (https=)
CN (2) CN113227144B (https=)
AU (1) AU2019378039A1 (https=)
CA (1) CA3119296A1 (https=)
MA (1) MA53877A (https=)
SG (1) SG11202104334SA (https=)
WO (1) WO2020102589A1 (https=)

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Publication number Priority date Publication date Assignee Title
CN113713091A (zh) 2015-02-06 2021-11-30 新加坡国立大学 工程免疫细胞及其用途和生产方法
SG11201903830TA (en) 2016-11-22 2019-05-30 Nat Univ Singapore Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies
GB201719646D0 (en) 2017-11-27 2018-01-10 Bivictrix Therapeutics Ltd Therapy
CN112300282A (zh) * 2020-11-03 2021-02-02 南京北恒生物科技有限公司 靶向cd7的人源化抗体及其用途
CN114525259B (zh) * 2020-11-03 2025-02-14 南京北恒生物科技有限公司 靶向cd7的嵌合抗原受体及其用途
CN114525306B (zh) * 2020-11-23 2025-01-28 博生吉医药科技(苏州)有限公司 一种cd7-car-t细胞的制备方法及应用
GB202020572D0 (en) * 2020-12-23 2021-02-03 Bivictrix Therapeutics Ltd Novel methods of therapy
GB202020573D0 (en) * 2020-12-23 2021-02-03 Bivictrix Therapeutics Ltd Novel methods of therapy
CN115786271B (zh) * 2021-01-12 2025-07-22 上海雅科生物科技有限公司 靶向cd7的工程化免疫细胞、嵌合抗原受体、cd7阻断分子及应用
US20250099504A1 (en) * 2022-03-29 2025-03-27 Institute Of Hematology And Blood Diseases Hospital , Chinese Academy Of Medical Sciences Antibody that specifically binds to cd7 and use thereof in preparing chimeric antigen receptor
CN120025438A (zh) * 2023-11-21 2025-05-23 合源生物科技(天津)有限公司 一种靶向cd7的人源化抗体、嵌合抗原受体及其应用
CN118221810A (zh) * 2024-03-05 2024-06-21 武汉生物制品研究所有限责任公司 一种能够结合ev-a71的单克隆抗体及其应用
CN120865430A (zh) * 2024-04-30 2025-10-31 合源生物科技(天津)有限公司 一种增强型嵌合抗原受体及其应用

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JP2016508728A (ja) * 2013-02-26 2016-03-24 メモリアル スローン−ケタリング キャンサー センター 免疫療法のための組成物および方法
WO2017149515A1 (en) * 2016-03-04 2017-09-08 Novartis Ag Cells expressing multiple chimeric antigen receptor (car) molecules and uses therefore
WO2018098306A1 (en) * 2016-11-22 2018-05-31 National University Of Singapore Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies
JP2020530291A (ja) * 2017-08-10 2020-10-22 ナショナル ユニバーシティ オブ シンガポール Ｔ細胞受容体欠損キメラ抗原受容体ｔ細胞およびその使用方法

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