JPWO2020102589A5 - - Google Patents
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- Publication number
- JPWO2020102589A5 JPWO2020102589A5 JP2021525298A JP2021525298A JPWO2020102589A5 JP WO2020102589 A5 JPWO2020102589 A5 JP WO2020102589A5 JP 2021525298 A JP2021525298 A JP 2021525298A JP 2021525298 A JP2021525298 A JP 2021525298A JP WO2020102589 A5 JPWO2020102589 A5 JP WO2020102589A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- retroviral vector
- acid sequence
- promoter
- bicistronic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025001976A JP2025072367A (ja) | 2018-11-14 | 2025-01-06 | Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862767069P | 2018-11-14 | 2018-11-14 | |
| US62/767,069 | 2018-11-14 | ||
| PCT/US2019/061549 WO2020102589A1 (en) | 2018-11-14 | 2019-11-14 | Two-gene vectors for generating car-t cells and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025001976A Division JP2025072367A (ja) | 2018-11-14 | 2025-01-06 | Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022512994A JP2022512994A (ja) | 2022-02-07 |
| JP2022512994A5 JP2022512994A5 (https=) | 2022-11-22 |
| JPWO2020102589A5 true JPWO2020102589A5 (https=) | 2022-11-22 |
Family
ID=70732194
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021525298A Pending JP2022512994A (ja) | 2018-11-14 | 2019-11-14 | Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 |
| JP2025001976A Pending JP2025072367A (ja) | 2018-11-14 | 2025-01-06 | Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025001976A Pending JP2025072367A (ja) | 2018-11-14 | 2025-01-06 | Ｃａｒ－ｔ細胞を生成する２遺伝子ベクターおよびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20210395779A1 (https=) |
| EP (1) | EP3864052A4 (https=) |
| JP (2) | JP2022512994A (https=) |
| KR (1) | KR20210091250A (https=) |
| CN (2) | CN113227144B (https=) |
| AU (1) | AU2019378039A1 (https=) |
| CA (1) | CA3119296A1 (https=) |
| MA (1) | MA53877A (https=) |
| SG (1) | SG11202104334SA (https=) |
| WO (1) | WO2020102589A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113713091A (zh) | 2015-02-06 | 2021-11-30 | 新加坡国立大学 | 工程免疫细胞及其用途和生产方法 |
| SG11201903830TA (en) | 2016-11-22 | 2019-05-30 | Nat Univ Singapore | Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies |
| GB201719646D0 (en) | 2017-11-27 | 2018-01-10 | Bivictrix Therapeutics Ltd | Therapy |
| CN112300282A (zh) * | 2020-11-03 | 2021-02-02 | 南京北恒生物科技有限公司 | 靶向cd7的人源化抗体及其用途 |
| CN114525259B (zh) * | 2020-11-03 | 2025-02-14 | 南京北恒生物科技有限公司 | 靶向cd7的嵌合抗原受体及其用途 |
| CN114525306B (zh) * | 2020-11-23 | 2025-01-28 | 博生吉医药科技(苏州)有限公司 | 一种cd7-car-t细胞的制备方法及应用 |
| GB202020572D0 (en) * | 2020-12-23 | 2021-02-03 | Bivictrix Therapeutics Ltd | Novel methods of therapy |
| GB202020573D0 (en) * | 2020-12-23 | 2021-02-03 | Bivictrix Therapeutics Ltd | Novel methods of therapy |
| CN115786271B (zh) * | 2021-01-12 | 2025-07-22 | 上海雅科生物科技有限公司 | 靶向cd7的工程化免疫细胞、嵌合抗原受体、cd7阻断分子及应用 |
| US20250099504A1 (en) * | 2022-03-29 | 2025-03-27 | Institute Of Hematology And Blood Diseases Hospital , Chinese Academy Of Medical Sciences | Antibody that specifically binds to cd7 and use thereof in preparing chimeric antigen receptor |
| CN120025438A (zh) * | 2023-11-21 | 2025-05-23 | 合源生物科技(天津)有限公司 | 一种靶向cd7的人源化抗体、嵌合抗原受体及其应用 |
| CN118221810A (zh) * | 2024-03-05 | 2024-06-21 | 武汉生物制品研究所有限责任公司 | 一种能够结合ev-a71的单克隆抗体及其应用 |
| CN120865430A (zh) * | 2024-04-30 | 2025-10-31 | 合源生物科技(天津)有限公司 | 一种增强型嵌合抗原受体及其应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260203A (en) | 1986-09-02 | 1993-11-09 | Enzon, Inc. | Single polypeptide chain binding molecules |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| ATE87659T1 (de) | 1986-09-02 | 1993-04-15 | Enzon Lab Inc | Bindungsmolekuele mit einzelpolypeptidkette. |
| CA2386270A1 (en) | 1999-10-15 | 2001-04-26 | University Of Massachusetts | Rna interference pathway genes as tools for targeted genetic interference |
| US6326193B1 (en) | 1999-11-05 | 2001-12-04 | Cambria Biosciences, Llc | Insect control agent |
| AU2001275474A1 (en) | 2000-06-12 | 2001-12-24 | Akkadix Corporation | Materials and methods for the control of nematodes |
| DK2958943T3 (da) * | 2013-02-20 | 2019-12-09 | Univ Pennsylvania | Behandling af cancer ved anvendelse af humaniseret anti-EGFRvIII kimær antigenreceptor |
| PT2961831T (pt) * | 2013-02-26 | 2020-10-12 | Memorial Sloan Kettering Cancer Center | Composições e métodos para imunoterapêutica |
| WO2016049024A2 (en) * | 2014-09-24 | 2016-03-31 | The Broad Institute Inc. | Delivery, use and therapeutic applications of the crispr-cas systems and compositions for modeling competition of multiple cancer mutations in vivo |
| CN113713091A (zh) | 2015-02-06 | 2021-11-30 | 新加坡国立大学 | 工程免疫细胞及其用途和生产方法 |
| AU2017225733A1 (en) * | 2016-03-04 | 2018-09-27 | Novartis Ag | Cells expressing multiple chimeric antigen receptor (CAR) molecules and uses therefore |
| SG11201903830TA (en) | 2016-11-22 | 2019-05-30 | Nat Univ Singapore | Blockade of cd7 expression and chimeric antigen receptors for immunotherapy of t-cell malignancies |
| US20190038733A1 (en) * | 2017-08-10 | 2019-02-07 | National University Of Singapore | T cell receptor-deficient chimeric antigen receptor t-cells and methods of use thereof |
| WO2019226946A1 (en) * | 2018-05-23 | 2019-11-28 | National University Of Singapore | Chimeric antigen receptors and gene editing of cd2 for immunotherapy of t-cell malignancies |
| KR20210008408A (ko) * | 2018-05-23 | 2021-01-21 | 싱가포르국립대학교 | T-세포 악성 종양의 면역요법을 위한 cd2 표면 발현 및 키메라 항원 수용체의 발현에 대한 차단 |
-
2019
- 2019-11-14 KR KR1020217017844A patent/KR20210091250A/ko not_active Ceased
- 2019-11-14 WO PCT/US2019/061549 patent/WO2020102589A1/en not_active Ceased
- 2019-11-14 JP JP2021525298A patent/JP2022512994A/ja active Pending
- 2019-11-14 AU AU2019378039A patent/AU2019378039A1/en active Pending
- 2019-11-14 CA CA3119296A patent/CA3119296A1/en active Pending
- 2019-11-14 SG SG11202104334SA patent/SG11202104334SA/en unknown
- 2019-11-14 MA MA053877A patent/MA53877A/fr unknown
- 2019-11-14 CN CN201980082104.2A patent/CN113227144B/zh active Active
- 2019-11-14 US US17/291,580 patent/US20210395779A1/en active Pending
- 2019-11-14 EP EP19883740.3A patent/EP3864052A4/en active Pending
- 2019-11-14 CN CN202510607212.4A patent/CN120519520A/zh active Pending
-
2025
- 2025-01-06 JP JP2025001976A patent/JP2025072367A/ja active Pending
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