JP2022512911A - ａｐｏ（ａ）を標的化するコンジュゲートアンチセンス化合物を用いて心血管事象のリスクを低減する方法 - Google Patents

ａｐｏ（ａ）を標的化するコンジュゲートアンチセンス化合物を用いて心血管事象のリスクを低減する方法 Download PDF

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JP2022512911A
JP2022512911A JP2021524019A JP2021524019A JP2022512911A JP 2022512911 A JP2022512911 A JP 2022512911A JP 2021524019 A JP2021524019 A JP 2021524019A JP 2021524019 A JP2021524019 A JP 2021524019A JP 2022512911 A JP2022512911 A JP 2022512911A
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レソゴール，アナスタシア
シャオ，キング
スレン，トム
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ノバルティス アーゲー
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JP2021524019A 2018-11-09 2019-11-08 ａｐｏ（ａ）を標的化するコンジュゲートアンチセンス化合物を用いて心血管事象のリスクを低減する方法 Pending JP2022512911A (ja)

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JP2024031803A JP2024081645A (ja) 2018-11-09 2024-03-04 ａｐｏ（ａ）を標的化するコンジュゲートアンチセンス化合物を用いて心血管事象のリスクを低減する方法
JP2025169038A JP2026021335A (ja) 2018-11-09 2025-10-07 ａｐｏ（ａ）を標的化するコンジュゲートアンチセンス化合物を用いて心血管事象のリスクを低減する方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862758323P 2018-11-09 2018-11-09
US62/758,323 2018-11-09
US201962874459P 2019-07-15 2019-07-15
US62/874,459 2019-07-15
PCT/IB2019/059632 WO2020095274A1 (en) 2018-11-09 2019-11-08 Method for reducing the risk of a cardiovascular event with conjugated antisense compounds targeting apo(a)

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JP2024031803A Division JP2024081645A (ja) 2018-11-09 2024-03-04 ａｐｏ（ａ）を標的化するコンジュゲートアンチセンス化合物を用いて心血管事象のリスクを低減する方法

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JP2022512911A true JP2022512911A (ja) 2022-02-07
JP2022512911A5 JP2022512911A5 (https=) 2022-11-11

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JP2021524019A Pending JP2022512911A (ja) 2018-11-09 2019-11-08 ａｐｏ（ａ）を標的化するコンジュゲートアンチセンス化合物を用いて心血管事象のリスクを低減する方法
JP2024031803A Pending JP2024081645A (ja) 2018-11-09 2024-03-04 ａｐｏ（ａ）を標的化するコンジュゲートアンチセンス化合物を用いて心血管事象のリスクを低減する方法
JP2025169038A Pending JP2026021335A (ja) 2018-11-09 2025-10-07 ａｐｏ（ａ）を標的化するコンジュゲートアンチセンス化合物を用いて心血管事象のリスクを低減する方法

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JP2024031803A Pending JP2024081645A (ja) 2018-11-09 2024-03-04 ａｐｏ（ａ）を標的化するコンジュゲートアンチセンス化合物を用いて心血管事象のリスクを低減する方法
JP2025169038A Pending JP2026021335A (ja) 2018-11-09 2025-10-07 ａｐｏ（ａ）を標的化するコンジュゲートアンチセンス化合物を用いて心血管事象のリスクを低減する方法

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US (2) US20210395737A1 (https=)
EP (1) EP3877523A1 (https=)
JP (3) JP2022512911A (https=)
KR (2) KR20260037169A (https=)
CN (1) CN113286885A (https=)
AU (3) AU2019377275A1 (https=)
CA (1) CA3111382A1 (https=)
IL (1) IL281147A (https=)
WO (1) WO2020095274A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021013807A2 (pt) 2019-01-18 2021-11-30 Astrazeneca Ab Inibidores de pcsk9 e seus métodos de uso
MX2021008661A (es) 2019-01-18 2021-08-19 Astrazeneca Ab Inhibidores de la pcsk9 y metodos de uso de los mismos.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599706A (en) 1994-09-23 1997-02-04 Stinchcomb; Dan T. Ribozymes targeted to apo(a) mRNA
US7227014B2 (en) 2001-08-07 2007-06-05 Isis Pharmaceuticals, Inc. Antisense modulation of apolipoprotein (a) expression
US7259150B2 (en) 2001-08-07 2007-08-21 Isis Pharmaceuticals, Inc. Modulation of apolipoprotein (a) expression
WO2003014397A1 (en) 2001-08-09 2003-02-20 Biomedlab Corporation Probe for detection of enteric virus detection kit and method for enteric virus with the same
EP3822352A3 (en) 2012-05-24 2021-11-03 Ionis Pharmaceuticals, Inc. Methods and compositions for modulating apolipoprotein(a) expression
DK2992098T3 (da) 2013-05-01 2019-06-17 Ionis Pharmaceuticals Inc Sammensætninger og fremgangsmåder til modulering af hbv- og ttr-ekspression
US9382540B2 (en) * 2014-05-01 2016-07-05 Isis Pharmaceuticals, Inc Compositions and methods for modulating angiopoietin-like 3 expression
KR20250078597A (ko) 2015-11-06 2025-06-02 아이오니스 파마수티컬즈, 인코포레이티드 아포리포프로테인 (a) 발현 조정
PL4119569T3 (pl) * 2015-11-06 2024-11-18 Ionis Pharmaceuticals, Inc. Sprzężone związki antysensowne do zastosowania w terapii

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Publication number Publication date
US20210395737A1 (en) 2021-12-23
KR20210091703A (ko) 2021-07-22
WO2020095274A1 (en) 2020-05-14
AU2019377275A1 (en) 2021-03-25
EP3877523A1 (en) 2021-09-15
JP2026021335A (ja) 2026-02-10
US20260049310A1 (en) 2026-02-19
KR20260037169A (ko) 2026-03-17
CN113286885A (zh) 2021-08-20
JP2024081645A (ja) 2024-06-18
CA3111382A1 (en) 2020-05-14
AU2025267467A1 (en) 2025-12-04
AU2023210550A1 (en) 2023-08-24
IL281147A (en) 2021-04-29

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