JP2022512128A5 - - Google Patents
Info
- Publication number
- JP2022512128A5 JP2022512128A5 JP2021532111A JP2021532111A JP2022512128A5 JP 2022512128 A5 JP2022512128 A5 JP 2022512128A5 JP 2021532111 A JP2021532111 A JP 2021532111A JP 2021532111 A JP2021532111 A JP 2021532111A JP 2022512128 A5 JP2022512128 A5 JP 2022512128A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- hydroxy
- azaspiro
- decane
- carbonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1819937.2A GB201819937D0 (en) | 2018-12-06 | 2018-12-06 | Pharmaceutical compounds |
| GB1819937.2 | 2018-12-06 | ||
| GBGB1904339.7A GB201904339D0 (en) | 2019-03-28 | 2019-03-28 | Pharmaceutical compounds |
| GB1904339.7 | 2019-03-28 | ||
| GB1911311.7 | 2019-08-07 | ||
| GBGB1911311.7A GB201911311D0 (en) | 2019-08-07 | 2019-08-07 | Pharmaceutical compounds |
| PCT/GB2019/053457 WO2020115501A1 (en) | 2018-12-06 | 2019-12-06 | Pharmaceutical compounds and their use as inhibitors of ubiquitin specific protease 19 (usp19) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022512128A JP2022512128A (ja) | 2022-02-02 |
| JP2022512128A5 true JP2022512128A5 (enExample) | 2023-01-11 |
Family
ID=68887435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021532111A Pending JP2022512128A (ja) | 2018-12-06 | 2019-12-06 | 医薬化合物およびユビキチン特異的プロテアーゼ１９（ｕｓｐ１９）阻害剤としてのその使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20220033397A1 (enExample) |
| EP (1) | EP3890829A1 (enExample) |
| JP (1) | JP2022512128A (enExample) |
| KR (1) | KR20210102285A (enExample) |
| CN (1) | CN113365696A (enExample) |
| AU (1) | AU2019393162A1 (enExample) |
| BR (1) | BR112021010644A2 (enExample) |
| CA (1) | CA3121376A1 (enExample) |
| IL (1) | IL283706A (enExample) |
| MX (1) | MX2021006540A (enExample) |
| SG (1) | SG11202105913RA (enExample) |
| WO (1) | WO2020115501A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201801562D0 (en) * | 2018-01-31 | 2018-03-14 | Almac Diagnostics Ltd | Pharmaceutical compounds |
| GB202104097D0 (en) * | 2021-03-24 | 2021-05-05 | Almac Discovery Ltd | Pharmaceutical compounds |
| GB202311227D0 (en) | 2023-07-21 | 2023-09-06 | Almac Discovery Ltd | Pharmaceutical compounds |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPO111096A0 (en) * | 1996-07-18 | 1996-08-08 | Fujisawa Pharmaceutical Co., Ltd. | New compound |
| WO2003029209A2 (en) | 2001-10-02 | 2003-04-10 | Smithkline Beecham Corporation | Chemical compounds |
| EP2565186A1 (en) * | 2011-09-02 | 2013-03-06 | Hybrigenics S.A. | Selective and reversible inhibitors of ubiquitin specific protease 7 |
| MA41291A (fr) * | 2014-12-30 | 2017-11-07 | Forma Therapeutics Inc | Dérivés de la pyrrolotriazinone et de l'imidazotriazinone en tant qu'inhibiteurs de la protéase spécifique de l'ubiquitine n° 7 (usp7) pour le traitement d'un cancer |
| AR103297A1 (es) * | 2014-12-30 | 2017-05-03 | Forma Therapeutics Inc | Pirrolo y pirazolopirimidinas como inhibidores de la proteasa 7 específica de ubiquitina |
| US9938300B2 (en) * | 2015-02-05 | 2018-04-10 | Forma Therapeutics, Inc. | Isothiazolopyrimidinones, pyrazolopyrimidinones, and pyrrolopyrimidinones as ubiquitin-specific protease 7 inhibitors |
| US9840491B2 (en) * | 2015-02-05 | 2017-12-12 | Forma Therapeutics, Inc. | Quinazolinones and azaquinazolinones as ubiquitin-specific protease 7 inhibitors |
| EP3253765A1 (en) * | 2015-02-05 | 2017-12-13 | Forma Therapeutics, Inc. | Thienopyrimidinones as ubiquitin-specific protease 7 inhibitors |
| FR3052452B1 (fr) * | 2016-06-10 | 2018-06-22 | Les Laboratoires Servier | Nouveaux derives de piperidinyle, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| GEP20207161B (en) * | 2016-06-10 | 2020-10-12 | Servier Lab | New (hetero)aryl-substituted-piperidinyl derivatives, a process for their preparation and pharmaceutical compositions containing them |
| GB201612938D0 (en) * | 2016-07-26 | 2016-09-07 | Almac Discovery Ltd | Pharmaceutical compounds |
| GB201801562D0 (en) * | 2018-01-31 | 2018-03-14 | Almac Diagnostics Ltd | Pharmaceutical compounds |
-
2019
- 2019-12-06 CN CN201980090768.3A patent/CN113365696A/zh active Pending
- 2019-12-06 CA CA3121376A patent/CA3121376A1/en active Pending
- 2019-12-06 MX MX2021006540A patent/MX2021006540A/es unknown
- 2019-12-06 KR KR1020217020079A patent/KR20210102285A/ko not_active Withdrawn
- 2019-12-06 EP EP19821176.5A patent/EP3890829A1/en not_active Withdrawn
- 2019-12-06 JP JP2021532111A patent/JP2022512128A/ja active Pending
- 2019-12-06 BR BR112021010644-8A patent/BR112021010644A2/pt not_active Application Discontinuation
- 2019-12-06 AU AU2019393162A patent/AU2019393162A1/en not_active Abandoned
- 2019-12-06 US US17/299,959 patent/US20220033397A1/en not_active Abandoned
- 2019-12-06 WO PCT/GB2019/053457 patent/WO2020115501A1/en not_active Ceased
- 2019-12-06 SG SG11202105913RA patent/SG11202105913RA/en unknown
-
2021
- 2021-06-03 IL IL283706A patent/IL283706A/en unknown
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