JP2022512043A5 - - Google Patents

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Publication number
JP2022512043A5
JP2022512043A5 JP2021547634A JP2021547634A JP2022512043A5 JP 2022512043 A5 JP2022512043 A5 JP 2022512043A5 JP 2021547634 A JP2021547634 A JP 2021547634A JP 2021547634 A JP2021547634 A JP 2021547634A JP 2022512043 A5 JP2022512043 A5 JP 2022512043A5
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JP
Japan
Prior art keywords
fusion protein
protein according
cancer
identification number
sequence identification
Prior art date
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Granted
Application number
JP2021547634A
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English (en)
Japanese (ja)
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JP2022512043A (ja
JP7496091B2 (ja
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Priority claimed from PCT/CN2019/114026 external-priority patent/WO2020088459A1/en
Publication of JP2022512043A publication Critical patent/JP2022512043A/ja
Publication of JP2022512043A5 publication Critical patent/JP2022512043A5/ja
Application granted granted Critical
Publication of JP7496091B2 publication Critical patent/JP7496091B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021547634A 2018-10-29 2019-10-29 合理的に設計された新規なタンパク質組成物 Active JP7496091B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862752293P 2018-10-29 2018-10-29
US62/752,293 2018-10-29
US201962811116P 2019-02-27 2019-02-27
US62/811,116 2019-02-27
PCT/CN2019/114026 WO2020088459A1 (en) 2018-10-29 2019-10-29 Novel rationally designed protein compositions

Publications (3)

Publication Number Publication Date
JP2022512043A JP2022512043A (ja) 2022-02-01
JP2022512043A5 true JP2022512043A5 (https=) 2022-10-26
JP7496091B2 JP7496091B2 (ja) 2024-06-06

Family

ID=70462528

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021547634A Active JP7496091B2 (ja) 2018-10-29 2019-10-29 合理的に設計された新規なタンパク質組成物

Country Status (12)

Country Link
US (1) US12378295B2 (https=)
EP (1) EP3873945A4 (https=)
JP (1) JP7496091B2 (https=)
KR (1) KR20210087965A (https=)
CN (1) CN113166272B (https=)
AU (1) AU2019371994A1 (https=)
BR (1) BR112021008204A2 (https=)
CA (1) CA3117853A1 (https=)
MX (1) MX2021004916A (https=)
SG (1) SG11202104297XA (https=)
TW (1) TWI840433B (https=)
WO (1) WO2020088459A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12247060B2 (en) 2018-01-09 2025-03-11 Marengo Therapeutics, Inc. Calreticulin binding constructs and engineered T cells for the treatment of diseases
EP3765517A1 (en) 2018-03-14 2021-01-20 Elstar Therapeutics, Inc. Multifunctional molecules that bind to calreticulin and uses thereof
CA3105448A1 (en) 2018-07-03 2020-01-09 Elstar Therapeutics, Inc. Anti-tcr antibody molecules and uses thereof
MX2021002077A (es) * 2018-08-20 2021-05-27 1Globe Biomedical Co Ltd Nuevas composiciones de anticuerpos para la inmunoterapia contra el cáncer.
GB2599228B (en) 2019-02-21 2024-02-07 Marengo Therapeutics Inc Multifunctional molecules that bind to T cell related cancer cells and uses thereof
CN119039441A (zh) 2019-02-21 2024-11-29 马伦戈治疗公司 与nkp30结合的抗体分子及其用途
AU2020416273A1 (en) 2020-01-03 2022-07-28 Marengo Therapeutics, Inc. Anti-TCR antibody molecules and uses thereof
IL298136A (en) 2020-05-13 2023-01-01 Bonum Therapeutics Inc Preparations of protein complexes and methods of using them
EP4174088A4 (en) * 2020-06-30 2024-01-24 GI Innovation, Inc. FUSION PROTEIN COMPRISING AN ANTI-LAG-3 AND IL-2 ANTIBODY AND USE THEREOF
US20230242607A1 (en) * 2020-07-09 2023-08-03 Eutilex Co., Ltd. Il-2 variants
KR20230112632A (ko) 2020-10-23 2023-07-27 애셔 바이오테라퓨틱스, 인크. 면역 세포 기능을 조절하기 위한 cd8 항원 결합 분자와의 융합
WO2022115865A2 (en) 2020-11-25 2022-06-02 Xilio Development, Inc. Tumor-specific cleavable linkers
AU2022306974A1 (en) 2021-07-09 2024-01-04 Bright Peak Therapeutics Ag Modified il-2 polypeptides for treatment of inflammatory and autoimmune diseases
AU2023226512A1 (en) 2022-02-23 2024-08-29 Bright Peak Therapeutics Ag Immune antigen specific il-18 immunocytokines and uses thereof
CN120518765A (zh) * 2025-02-08 2025-08-22 龙启生物科技(上海)有限公司 一种结合人CD8β的VHH及其应用

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
GB9014932D0 (en) 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
JPH05244982A (ja) 1991-12-06 1993-09-24 Sumitomo Chem Co Ltd 擬人化b−b10
GB9722131D0 (en) 1997-10-20 1997-12-17 Medical Res Council Method
US20040202995A1 (en) 2003-04-09 2004-10-14 Domantis Nucleic acids, proteins, and screening methods
CU23923B1 (es) 2010-11-12 2013-07-31 Ct De Inmunología Molecular Polipéptidos derivados de la il-2 con actividad agonista
SG192673A1 (en) * 2011-02-10 2013-09-30 Roche Glycart Ag Mutant interleukin-2 polypeptides
RU2769282C2 (ru) * 2016-06-20 2022-03-30 Кимаб Лимитед Анти-PD-L1 и IL-2 цитокины
CN107915777A (zh) * 2016-10-09 2018-04-17 泰州迈博太科药业有限公司 一种重组免疫细胞因子及其应用
MY201482A (en) * 2017-04-03 2024-02-26 Hoffmann La Roche Immunoconjugates of an anti-pd-1 antibody with a mutant il-2 or with il-15
JP7148539B2 (ja) * 2017-04-03 2022-10-05 エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト 免疫抱合体

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