JP2022511390A5 - - Google Patents
Info
- Publication number
- JP2022511390A5 JP2022511390A5 JP2021517768A JP2021517768A JP2022511390A5 JP 2022511390 A5 JP2022511390 A5 JP 2022511390A5 JP 2021517768 A JP2021517768 A JP 2021517768A JP 2021517768 A JP2021517768 A JP 2021517768A JP 2022511390 A5 JP2022511390 A5 JP 2022511390A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- peptide
- amino acid
- residue
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024175673A JP2025013348A (ja) | 2018-11-20 | 2024-10-07 | 分割インターロイキン模倣体およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862770152P | 2018-11-20 | 2018-11-20 | |
| US62/770,152 | 2018-11-20 | ||
| PCT/US2019/062198 WO2020106708A1 (en) | 2018-11-20 | 2019-11-19 | Split interleukin mimetics and their use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024175673A Division JP2025013348A (ja) | 2018-11-20 | 2024-10-07 | 分割インターロイキン模倣体およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022511390A JP2022511390A (ja) | 2022-01-31 |
| JP2022511390A5 true JP2022511390A5 (https=) | 2022-11-24 |
Family
ID=69500815
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021517768A Pending JP2022511390A (ja) | 2018-11-20 | 2019-11-19 | 分割インターロイキン模倣体およびその使用 |
| JP2024175673A Pending JP2025013348A (ja) | 2018-11-20 | 2024-10-07 | 分割インターロイキン模倣体およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024175673A Pending JP2025013348A (ja) | 2018-11-20 | 2024-10-07 | 分割インターロイキン模倣体およびその使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US12234572B2 (https=) |
| EP (1) | EP3883956A1 (https=) |
| JP (2) | JP2022511390A (https=) |
| KR (1) | KR20210094531A (https=) |
| CN (2) | CN112912388A (https=) |
| AU (1) | AU2019384523B2 (https=) |
| BR (1) | BR112021008985A2 (https=) |
| CA (1) | CA3119472A1 (https=) |
| EA (1) | EA202190593A1 (https=) |
| IL (1) | IL283217A (https=) |
| MX (1) | MX2021005593A (https=) |
| SG (1) | SG11202103045SA (https=) |
| WO (1) | WO2020106708A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12247060B2 (en) | 2018-01-09 | 2025-03-11 | Marengo Therapeutics, Inc. | Calreticulin binding constructs and engineered T cells for the treatment of diseases |
| EP3765517A1 (en) | 2018-03-14 | 2021-01-20 | Elstar Therapeutics, Inc. | Multifunctional molecules that bind to calreticulin and uses thereof |
| KR20210025522A (ko) * | 2018-06-25 | 2021-03-09 | 유니버시티 오브 워싱톤 | 강력하고 선택적인 인터루킨 모방체의 드 노보 디자인 |
| CA3105448A1 (en) | 2018-07-03 | 2020-01-09 | Elstar Therapeutics, Inc. | Anti-tcr antibody molecules and uses thereof |
| JP2022511390A (ja) | 2018-11-20 | 2022-01-31 | ユニバーシティ オブ ワシントン | 分割インターロイキン模倣体およびその使用 |
| CN119039441A (zh) | 2019-02-21 | 2024-11-29 | 马伦戈治疗公司 | 与nkp30结合的抗体分子及其用途 |
| GB2599228B (en) | 2019-02-21 | 2024-02-07 | Marengo Therapeutics Inc | Multifunctional molecules that bind to T cell related cancer cells and uses thereof |
| AU2020416273A1 (en) | 2020-01-03 | 2022-07-28 | Marengo Therapeutics, Inc. | Anti-TCR antibody molecules and uses thereof |
| CA3210492A1 (en) * | 2021-02-05 | 2022-08-11 | Dharmacon, Inc. | Fusion proteins for crispr-based transcriptional repression |
| WO2023044318A2 (en) * | 2021-09-15 | 2023-03-23 | Neoleukin Therapeutics, Inc. | Interleukin-2 receptor βeta (il-2rβ) binding polypeptides |
| AU2023208426A1 (en) * | 2022-01-24 | 2024-07-25 | Novimmune Sa | Composition and methods for the selective activation of cytokine signaling pathways |
| AU2024233726A1 (en) | 2023-03-07 | 2025-08-21 | Chugai Seiyaku Kabushiki Kaisha | Conditionally activated receptor signaling by using scaffold protein |
| EP4722235A1 (en) * | 2023-05-24 | 2026-04-08 | Nantong Yichen Biopharma. Co. Ltd. | Polypeptide, and conjugate and use thereof |
| IL325764A (en) * | 2023-07-13 | 2026-03-01 | Outpace Bio Inc | Designed compositions of interleukin-2 cytokine and methods of use |
| WO2025212606A1 (en) * | 2024-04-01 | 2025-10-09 | Bio-Techne Corporation | Synthetic il-2 polypeptides and conjugates, compositions, and uses thereof |
| WO2026039791A1 (en) * | 2024-08-16 | 2026-02-19 | Regeneron Pharmaceuticals, Inc. | Tumor-targeted split il2 receptor agonists |
| WO2026078029A1 (en) * | 2024-10-10 | 2026-04-16 | F. Hoffmann-La Roche Ag | Splitted interleukin-2 prodrugs and uses thereof |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1015080A (en) | 1908-04-17 | 1912-01-16 | George I Rockwood | Apparatus for operating alarms or other devices. |
| US5229109A (en) | 1992-04-14 | 1993-07-20 | Board Of Regents, The University Of Texas System | Low toxicity interleukin-2 analogues for use in immunotherapy |
| US6955807B1 (en) | 1998-05-15 | 2005-10-18 | Bayer Pharmaceuticals Corporation | IL-2 selective agonists and antagonists |
| US6168785B1 (en) | 1998-07-16 | 2001-01-02 | Institut Pasteur | Biological applications of new peptides of IL-2 and derivatives and use as therapeutic agents |
| GB0019638D0 (en) * | 2000-08-09 | 2000-09-27 | European Molecular Biology Lab Embl | Peptide mimetics |
| WO2002101629A1 (en) * | 2001-06-07 | 2002-12-19 | Wyeth | Solution structure of il-13 and uses thereof |
| CN1930300A (zh) * | 2004-03-05 | 2007-03-14 | 希龙公司 | 预测患者治疗药物耐受性的体外试验系统 |
| US20110020269A1 (en) | 2007-05-08 | 2011-01-27 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for modifying t cell immune responses and inflammation |
| CA2813411C (en) | 2010-11-05 | 2016-08-02 | Rinat Neuroscience Corporation | Engineered polypeptide conjugates and methods for making thereof using transglutaminase |
| CA2860170C (en) | 2010-12-22 | 2022-06-14 | The Board Of Trustees Of The Leland Stanford Junior University | Superagonists and antagonists of interleukin-2 |
| US9844582B2 (en) | 2012-05-22 | 2017-12-19 | Massachusetts Institute Of Technology | Synergistic tumor treatment with extended-PK IL-2 and therapeutic agents |
| WO2015164815A1 (en) | 2014-04-24 | 2015-10-29 | The Board Of Trustees Of The Leland Stanford Junior University | Superagonists, partial agonists and antagonists of interleukin-2 |
| RU2708075C2 (ru) | 2014-04-30 | 2019-12-04 | Пфайзер Инк. | Конъюгаты анти-ртк7 антитело-лекарственное средство |
| AU2015301936B2 (en) | 2014-08-11 | 2019-03-07 | Delinia, Inc. | Modified IL-2 variants that selectively activate regulatory T cells for the treatment of autoimmune diseases |
| AR105616A1 (es) | 2015-05-07 | 2017-10-25 | Lilly Co Eli | Proteínas de fusión |
| WO2018153865A1 (en) | 2017-02-24 | 2018-08-30 | Philogen S.P.A. | Immunoconjugates with optimized linkers and orientation |
| SG10202110182PA (en) | 2017-03-15 | 2021-10-28 | Silverback Therapeutics Inc | Benzazepine compounds, conjugates, and uses thereof |
| KR20210025522A (ko) | 2018-06-25 | 2021-03-09 | 유니버시티 오브 워싱톤 | 강력하고 선택적인 인터루킨 모방체의 드 노보 디자인 |
| JP2022511390A (ja) | 2018-11-20 | 2022-01-31 | ユニバーシティ オブ ワシントン | 分割インターロイキン模倣体およびその使用 |
| US20220000921A1 (en) | 2018-11-20 | 2022-01-06 | Innovative Cellular Therapeutics Holdings, Ltd. | Modified Cell Expressing Therapeutic Agent and Uses thereof |
| US20220370563A1 (en) | 2019-10-25 | 2022-11-24 | Neoleukin Therapeutics, Inc. | Methods of administration of il-2 receptor agonists |
| AU2020414355A1 (en) | 2019-12-24 | 2022-08-11 | Neoleukin Therapeutics, Inc. | Combination therapy using an IL-2 receptor agonist and an immune checkpoint inhibitor |
| CN111040981A (zh) | 2019-12-26 | 2020-04-21 | 南昌大学 | 表达重组IL-2的重组大肠杆菌Nissle 1917及其功能验证方法 |
| US20230340071A1 (en) | 2020-03-16 | 2023-10-26 | Neoleukin Therapeutics, Inc. | Interleukin-2 Receptor Beta (IL-2RB) Binding Polypeptides |
-
2019
- 2019-11-19 JP JP2021517768A patent/JP2022511390A/ja active Pending
- 2019-11-19 SG SG11202103045SA patent/SG11202103045SA/en unknown
- 2019-11-19 KR KR1020217014525A patent/KR20210094531A/ko not_active Ceased
- 2019-11-19 MX MX2021005593A patent/MX2021005593A/es unknown
- 2019-11-19 CN CN201980070569.6A patent/CN112912388A/zh active Pending
- 2019-11-19 EA EA202190593A patent/EA202190593A1/ru unknown
- 2019-11-19 BR BR112021008985-3A patent/BR112021008985A2/pt not_active IP Right Cessation
- 2019-11-19 AU AU2019384523A patent/AU2019384523B2/en active Active
- 2019-11-19 CN CN202510054463.4A patent/CN120040576A/zh active Pending
- 2019-11-19 EP EP19848950.2A patent/EP3883956A1/en active Pending
- 2019-11-19 US US17/294,807 patent/US12234572B2/en active Active
- 2019-11-19 WO PCT/US2019/062198 patent/WO2020106708A1/en not_active Ceased
- 2019-11-19 CA CA3119472A patent/CA3119472A1/en active Pending
-
2021
- 2021-05-16 IL IL283217A patent/IL283217A/en unknown
-
2024
- 2024-10-07 JP JP2024175673A patent/JP2025013348A/ja active Pending
-
2025
- 2025-01-10 US US19/016,343 patent/US20250179690A1/en active Pending
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