JP2022506955A5 - - Google Patents
Info
- Publication number
- JP2022506955A5 JP2022506955A5 JP2021525113A JP2021525113A JP2022506955A5 JP 2022506955 A5 JP2022506955 A5 JP 2022506955A5 JP 2021525113 A JP2021525113 A JP 2021525113A JP 2021525113 A JP2021525113 A JP 2021525113A JP 2022506955 A5 JP2022506955 A5 JP 2022506955A5
- Authority
- JP
- Japan
- Prior art keywords
- lipid nanoparticles
- compound
- nanoparticles according
- approximately
- total lipids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862758055P | 2018-11-09 | 2018-11-09 | |
| US62/758,055 | 2018-11-09 | ||
| PCT/US2019/060595 WO2020097548A1 (en) | 2018-11-09 | 2019-11-08 | Lipid nanoparticle formulations |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022506955A JP2022506955A (ja) | 2022-01-17 |
| JP2022506955A5 true JP2022506955A5 (enExample) | 2022-11-07 |
| JP7506670B2 JP7506670B2 (ja) | 2024-06-26 |
Family
ID=70612210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021525113A Active JP7506670B2 (ja) | 2018-11-09 | 2019-11-08 | 脂質ナノ粒子製剤 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220001029A1 (enExample) |
| EP (1) | EP3877522A4 (enExample) |
| JP (1) | JP7506670B2 (enExample) |
| CN (1) | CN113728101A (enExample) |
| AU (1) | AU2019377131A1 (enExample) |
| CA (1) | CA3118559A1 (enExample) |
| WO (1) | WO2020097548A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20240586T1 (hr) | 2018-10-09 | 2024-07-19 | The University Of British Columbia | Sastavi i sustavi koji sadrže transfekcijske sposobne vezikle bez organskih otapala i deterdženta i s njim povezanim postupcima |
| KR20210105889A (ko) | 2018-11-09 | 2021-08-27 | 아뷰터스 바이오파마 코포레이션 | 지질 나노입자 제제 |
| CN114729376A (zh) | 2019-09-23 | 2022-07-08 | 欧米茄治疗公司 | 用于调节肝细胞核因子4α(HNF4α)基因表达的组合物和方法 |
| EP4048807A1 (en) | 2019-09-23 | 2022-08-31 | Omega Therapeutics, Inc. | Compositions and methods for modulating apolipoprotein b (apob) gene expression |
| CA3173528A1 (en) | 2020-03-11 | 2021-09-16 | Omega Therapeutics, Inc. | Compositions and methods for modulating forkhead box p3 (foxp3) gene expression |
| US12194157B2 (en) | 2020-04-09 | 2025-01-14 | Finncure Oy | Carrier for targeted delivery to a host |
| FI20215508A1 (en) | 2020-04-09 | 2021-10-10 | Niemelae Erik Johan | Mimetic nanoparticles to prevent the spread of new coronaviruses and reduce the rate of infection |
| CZ310613B6 (cs) | 2020-09-23 | 2026-01-28 | Ústav organické chemie a biochemie AV ČR, v. v. i. | Lipidoidy pro transfekci nukleových kyselin a jejich použití |
| EP4228658A4 (en) | 2020-10-14 | 2025-02-19 | George Mason Research Foundation, Inc. | IONIZABLE LIPIDS AND METHODS FOR THE PRODUCTION AND USE THEREOF |
| CN112980878B (zh) * | 2021-02-04 | 2023-03-31 | 中国农业科学院兰州兽医研究所 | Hdac8基因敲除的bhk-21细胞系及其构建方法和应用 |
| CN112877275B (zh) * | 2021-02-04 | 2023-03-31 | 中国农业科学院兰州兽医研究所 | Hdac2基因敲除的bhk-21细胞系及其构建方法和应用 |
| EP4367242A2 (en) | 2021-07-07 | 2024-05-15 | Omega Therapeutics, Inc. | Compositions and methods for modulating secreted frizzled receptor protein 1 (sfrp1) gene expression |
| CZ310443B6 (cs) | 2021-07-19 | 2025-06-25 | Ústav organické chemie a biochemie AV ČR, v. v. i. | Cyklohexanové lipidoidy pro transfekci nukleových kyselin a jejich použití |
| KR20230053998A (ko) | 2021-10-15 | 2023-04-24 | (주)지노믹트리 | mRNA 발현을 위한 유전자 구조체 |
| WO2023165582A1 (zh) * | 2022-03-04 | 2023-09-07 | 益杰立科(上海)生物科技有限公司 | 靶向递送系统和方法 |
| US20260077037A1 (en) * | 2022-07-04 | 2026-03-19 | Bharat Biotech International Limited | Cationic lipid based composition, formulation and use for nucleic acid vaccine delivery and preparation thereof |
| EP4716741A2 (en) | 2023-05-23 | 2026-04-01 | Flagship Labs 114, Inc. | Compositions and methods for reducing cxcl9, cxcl10, and cxcl11 gene expression |
| EP4722368A1 (en) | 2023-05-26 | 2026-04-08 | Samsung Biologics Co., Ltd. | Novel nucleic acid construct comprising poly(a) tail having secondary or tertiary structure and uses thereof |
| KR20250018367A (ko) | 2023-07-28 | 2025-02-05 | 한국과학기술원 | 히스톤 코드 리더 도메인을 포함하는 폴리펩티드 및 이의 용도 |
| WO2025144938A1 (en) | 2023-12-26 | 2025-07-03 | Emmune, Inc. | Systems for nucleic acid transfer |
| WO2025166325A1 (en) | 2024-02-02 | 2025-08-07 | Editas Medicine, Inc. | MODIFIED GUIDE RNAs |
| WO2025210520A1 (en) * | 2024-04-04 | 2025-10-09 | Genevant Sciences Gmbh | Lipid nanoparticles for inducing an immunological response |
| WO2025213138A1 (en) | 2024-04-05 | 2025-10-09 | Editas Medicine, Inc. | Crispr/rna-guided nuclease related methods and compositions for treating primary open angle glaucoma |
| CN120037202B (zh) * | 2025-01-14 | 2025-12-26 | 浙江大学 | 一种基于连接处含有分支结构的阳离子脂质的脂质纳米颗粒及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2811430A1 (en) * | 2010-09-30 | 2012-04-05 | Merck Sharp & Dohme Corp. | Low molecular weight cationic lipids for oligonucleotide delivery |
| EP3485913A1 (en) * | 2010-10-21 | 2019-05-22 | Sirna Therapeutics, Inc. | Low molecular weight cationic lipids for oligonucleotide delivery |
| US9126966B2 (en) * | 2011-08-31 | 2015-09-08 | Protiva Biotherapeutics, Inc. | Cationic lipids and methods of use thereof |
| EP2817287B1 (en) * | 2012-02-24 | 2018-10-03 | Arbutus Biopharma Corporation | Trialkyl cationic lipids and methods of use thereof |
| AU2013249548A1 (en) * | 2012-04-19 | 2014-11-06 | Sirna Therapeutics, Inc. | Novel diester and triester based low molecular weight, biodegradable cationic lipids for oligonucleotide delivery |
| JP6620093B2 (ja) * | 2013-07-23 | 2019-12-11 | アービュートゥス バイオファーマ コーポレイションＡｒｂｕｔｕｓ Ｂｉｏｐｈａｒｍａ Ｃｏｒｐｏｒａｔｉｏｎ | メッセンジャーｒｎａを送達するための組成物及び方法 |
| EP3201338B1 (en) * | 2014-10-02 | 2021-11-03 | Arbutus Biopharma Corporation | Compositions and methods for silencing hepatitis b virus gene expression |
| AU2017379901B2 (en) * | 2016-12-21 | 2024-02-15 | Arbutus Biopharma Corporation | Methods for ameliorating infusion reactions |
| KR20210105889A (ko) * | 2018-11-09 | 2021-08-27 | 아뷰터스 바이오파마 코포레이션 | 지질 나노입자 제제 |
-
2019
- 2019-11-08 CA CA3118559A patent/CA3118559A1/en active Pending
- 2019-11-08 WO PCT/US2019/060595 patent/WO2020097548A1/en not_active Ceased
- 2019-11-08 CN CN201980088382.9A patent/CN113728101A/zh active Pending
- 2019-11-08 AU AU2019377131A patent/AU2019377131A1/en active Pending
- 2019-11-08 US US17/291,960 patent/US20220001029A1/en not_active Abandoned
- 2019-11-08 JP JP2021525113A patent/JP7506670B2/ja active Active
- 2019-11-08 EP EP19882056.5A patent/EP3877522A4/en not_active Withdrawn
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