JP2022506898A5 - - Google Patents
Info
- Publication number
- JP2022506898A5 JP2022506898A5 JP2021525010A JP2021525010A JP2022506898A5 JP 2022506898 A5 JP2022506898 A5 JP 2022506898A5 JP 2021525010 A JP2021525010 A JP 2021525010A JP 2021525010 A JP2021525010 A JP 2021525010A JP 2022506898 A5 JP2022506898 A5 JP 2022506898A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- independently selected
- aryl
- ring
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862760248P | 2018-11-13 | 2018-11-13 | |
| US201862760279P | 2018-11-13 | 2018-11-13 | |
| US201862760244P | 2018-11-13 | 2018-11-13 | |
| US62/760,244 | 2018-11-13 | ||
| US62/760,248 | 2018-11-13 | ||
| US62/760,279 | 2018-11-13 | ||
| US201962795373P | 2019-01-22 | 2019-01-22 | |
| US62/795,373 | 2019-01-22 | ||
| US201962796361P | 2019-01-24 | 2019-01-24 | |
| US201962796356P | 2019-01-24 | 2019-01-24 | |
| US62/796,356 | 2019-01-24 | ||
| US62/796,361 | 2019-01-24 | ||
| PCT/US2019/060775 WO2020102100A1 (en) | 2018-11-13 | 2019-11-11 | Compounds and compositions for treating conditions associated with nlrp activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022506898A JP2022506898A (ja) | 2022-01-17 |
| JP2022506898A5 true JP2022506898A5 (enExample) | 2022-11-21 |
Family
ID=68916531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021525010A Pending JP2022506898A (ja) | 2018-11-13 | 2019-11-11 | Ｎｌｒｐ活性に関連する状態を処置するための化合物及び組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12134611B2 (enExample) |
| EP (1) | EP3880666B1 (enExample) |
| JP (1) | JP2022506898A (enExample) |
| CN (1) | CN113166081A (enExample) |
| ES (1) | ES2957692T3 (enExample) |
| WO (1) | WO2020102100A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11370776B2 (en) * | 2017-07-07 | 2022-06-28 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
| EP3823974A1 (en) | 2018-07-20 | 2021-05-26 | F. Hoffmann-La Roche AG | Sulfonimidamide compounds as inhibitors of interleukin-1 activity |
| US20220378801A1 (en) * | 2019-06-21 | 2022-12-01 | Ac Immune Sa | Novel compounds |
| US11932630B2 (en) | 2021-04-16 | 2024-03-19 | Novartis Ag | Heteroaryl aminopropanol derivatives |
| CN117185965B (zh) * | 2023-09-18 | 2024-10-11 | 安徽金桐精细化学有限公司 | 一种磺酸基丙烯酸盐复配表面活性剂的制备方法 |
| WO2025153532A1 (en) | 2024-01-16 | 2025-07-24 | NodThera Limited | Nlrp3 inhibitors and glp-1 agonists combination therapies |
| WO2026064385A1 (en) * | 2024-09-18 | 2026-03-26 | Ventus Therapeutics U.S., Inc. | Oxadiazolone inhibitors of nlrp3 and uses thereof |
| CN119775202A (zh) * | 2024-12-31 | 2025-04-08 | 河南旭瑞新材料科技有限公司 | 一种2-巯基烟酰甘氨酸的合成方法 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| US5116742A (en) | 1986-12-03 | 1992-05-26 | University Patents, Inc. | RNA ribozyme restriction endoribonucleases and methods |
| WO1991003553A1 (en) | 1989-09-05 | 1991-03-21 | Immunex Corporation | TUMOR NECROSIS FACTOR-α AND -β RECEPTORS |
| TW221049B (enExample) | 1991-12-20 | 1994-02-11 | Lilly Co Eli | |
| US5705398A (en) | 1994-03-02 | 1998-01-06 | The Scripps Research Institute | Methods for identifying inhibitors of LPS-mediated LBP binding |
| US6090382A (en) | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
| MX336813B (es) | 1996-02-09 | 2016-02-02 | Abbvie Biotechnology Ltd | Anticuerpos humanos que ligan el tnfa humano. |
| HRP20000724A2 (en) | 1998-05-05 | 2001-06-30 | Hoffmann La Roche | Pyrazole derivatives as p-38 map kinase inhibitors |
| PL2298743T3 (pl) | 2003-06-26 | 2013-02-28 | Novartis Ag | Inhibitory kinaz P38 na bazie 5-członowych heterocykli |
| US20080280910A1 (en) | 2007-03-22 | 2008-11-13 | Keith Allan Menear | Phthalazinone derivatives |
| US8884006B2 (en) | 2011-09-19 | 2014-11-11 | University Of Puerto Rico | Small-molecule inhibitors of Rac1 in metastatic breast cancer |
| ITMI20131658A1 (it) | 2013-10-08 | 2015-04-09 | Getters Spa | Combinazione di materiali per dispositivi di rilascio di mercurio e dispositivi contenenti detta combinazione di materiali |
| US9714288B2 (en) | 2014-09-30 | 2017-07-25 | The Regents Of The University Of California | Antisense compounds and uses thereof |
| KR102727059B1 (ko) * | 2015-02-16 | 2024-11-05 | 더 유니버서티 어브 퀸슬랜드 | 설포닐우레아와 관련 화합물 및 그 용도 |
| US11597706B2 (en) | 2016-04-18 | 2023-03-07 | Novartis Ag | Compounds and compositions for treating conditions associated with NLRP activity |
| ES2940611T3 (es) | 2016-04-18 | 2023-05-09 | Novartis Ag | Compuestos y composiciones para el tratamiento de afecciones asociadas a la actividad de NLRP |
| KR20180134395A (ko) | 2016-04-19 | 2018-12-18 | 인네이트 튜머 이뮤니티, 인코포레이티드 | Nlrp3 조정제 |
| ES2844184T3 (es) | 2016-06-14 | 2021-07-21 | Bristol Myers Squibb Co | 4-hidroxi-3-sulfonilpiridin-2(1H)-onas como agonistas del receptor de APJ |
| CA3047336A1 (en) | 2017-01-23 | 2018-07-26 | Jecure Therapeutics, Inc. | Chemical compounds as inhibitors of interleukin-1 activity |
| EP3634951B8 (en) | 2017-06-09 | 2024-08-21 | Zydus Lifesciences Limited | Novel substituted sulfoximine compounds |
| CN111094242B (zh) * | 2017-07-24 | 2024-02-09 | 诺华股份有限公司 | 用于治疗与nlrp活性相关的病症的化合物和组合物 |
| RS65492B1 (sr) | 2017-07-24 | 2024-05-31 | Novartis Ag | Jedinjenja i kompozicije za lečenje stanja povezanih sa aktivnošću nlrp |
| US11518739B2 (en) | 2017-08-15 | 2022-12-06 | Inflazome Limited | Sulfonamide carboxamide compounds |
| EP3823974A1 (en) | 2018-07-20 | 2021-05-26 | F. Hoffmann-La Roche AG | Sulfonimidamide compounds as inhibitors of interleukin-1 activity |
| GB201902327D0 (en) | 2019-02-20 | 2019-04-03 | Inflazome Ltd | Novel compounds |
| BR112021003665A2 (pt) | 2018-09-13 | 2021-05-18 | Bayer Aktiengesellschaft | derivados de heterocicleno como agentes de controle de pragas |
| AU2020208644A1 (en) | 2019-01-18 | 2021-08-26 | Nuvation Bio Inc. | Heterocyclic compounds as adenosine antagonists |
| US20220378801A1 (en) * | 2019-06-21 | 2022-12-01 | Ac Immune Sa | Novel compounds |
-
2019
- 2019-11-11 EP EP19821320.9A patent/EP3880666B1/en active Active
- 2019-11-11 US US17/292,887 patent/US12134611B2/en active Active
- 2019-11-11 WO PCT/US2019/060775 patent/WO2020102100A1/en not_active Ceased
- 2019-11-11 ES ES19821320T patent/ES2957692T3/es active Active
- 2019-11-11 CN CN201980078239.1A patent/CN113166081A/zh active Pending
- 2019-11-11 JP JP2021525010A patent/JP2022506898A/ja active Pending
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