JP2022501064A5 - - Google Patents

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Publication number
JP2022501064A5
JP2022501064A5 JP2021525114A JP2021525114A JP2022501064A5 JP 2022501064 A5 JP2022501064 A5 JP 2022501064A5 JP 2021525114 A JP2021525114 A JP 2021525114A JP 2021525114 A JP2021525114 A JP 2021525114A JP 2022501064 A5 JP2022501064 A5 JP 2022501064A5
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JP
Japan
Application number
JP2021525114A
Other languages
Japanese (ja)
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JP2022501064A (ja
JPWO2020097520A5 (https=
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/060556 external-priority patent/WO2020097520A1/en
Publication of JP2022501064A publication Critical patent/JP2022501064A/ja
Publication of JP2022501064A5 publication Critical patent/JP2022501064A5/ja
Publication of JPWO2020097520A5 publication Critical patent/JPWO2020097520A5/ja
Priority to JP2024202026A priority Critical patent/JP2025019119A/ja
Pending legal-status Critical Current

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JP2021525114A 2018-11-09 2019-11-08 ケイ素を含有するカチオン性脂質 Pending JP2022501064A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024202026A JP2025019119A (ja) 2018-11-09 2024-11-20 ケイ素を含有するカチオン性脂質

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862758108P 2018-11-09 2018-11-09
US62/758,108 2018-11-09
PCT/US2019/060556 WO2020097520A1 (en) 2018-11-09 2019-11-08 Cationic lipids containing silicon

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024202026A Division JP2025019119A (ja) 2018-11-09 2024-11-20 ケイ素を含有するカチオン性脂質

Publications (3)

Publication Number Publication Date
JP2022501064A JP2022501064A (ja) 2022-01-06
JP2022501064A5 true JP2022501064A5 (https=) 2022-11-04
JPWO2020097520A5 JPWO2020097520A5 (https=) 2022-11-04

Family

ID=70612265

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021525114A Pending JP2022501064A (ja) 2018-11-09 2019-11-08 ケイ素を含有するカチオン性脂質
JP2024202026A Pending JP2025019119A (ja) 2018-11-09 2024-11-20 ケイ素を含有するカチオン性脂質

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024202026A Pending JP2025019119A (ja) 2018-11-09 2024-11-20 ケイ素を含有するカチオン性脂質

Country Status (14)

Country Link
US (2) US12350383B2 (https=)
EP (1) EP3877001A4 (https=)
JP (2) JP2022501064A (https=)
KR (1) KR20210105888A (https=)
CN (1) CN113286622A (https=)
AU (1) AU2019376006A1 (https=)
BR (1) BR112021008953A2 (https=)
CA (1) CA3119051A1 (https=)
EA (1) EA202191315A1 (https=)
IL (1) IL282957A (https=)
MX (1) MX2021005462A (https=)
SG (1) SG11202104682PA (https=)
WO (1) WO2020097520A1 (https=)
ZA (1) ZA202103229B (https=)

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CN113166783B (zh) 2018-10-09 2024-10-11 不列颠哥伦比亚大学 包含无有机溶剂和去污剂的转染活性囊泡的组合物和系统以及与之相关的方法
CA3112837A1 (en) * 2018-10-19 2020-04-23 Translate Bio, Inc. Pumpless encapsulation of messenger rna
AU2020355000A1 (en) 2019-09-23 2022-03-17 Omega Therapeutics, Inc. Compositions and methods for modulating apolipoprotein B (APOB) gene expression
CN114729376A (zh) 2019-09-23 2022-07-08 欧米茄治疗公司 用于调节肝细胞核因子4α(HNF4α)基因表达的组合物和方法
CN116096886A (zh) 2020-03-11 2023-05-09 欧米茄治疗公司 用于调节叉头框p3(foxp3)基因表达的组合物和方法
AU2021305214A1 (en) * 2020-07-10 2023-02-23 Genevant Sciences Gmbh Lipid nanoparticles for delivering therapeutics to lungs
CZ310613B6 (cs) 2020-09-23 2026-01-28 Ústav organické chemie a biochemie AV ČR, v. v. i. Lipidoidy pro transfekci nukleových kyselin a jejich použití
EP4367242A2 (en) 2021-07-07 2024-05-15 Omega Therapeutics, Inc. Compositions and methods for modulating secreted frizzled receptor protein 1 (sfrp1) gene expression
CZ310443B6 (cs) 2021-07-19 2025-06-25 Ústav organické chemie a biochemie AV ČR, v. v. i. Cyklohexanové lipidoidy pro transfekci nukleových kyselin a jejich použití
WO2024243438A2 (en) 2023-05-23 2024-11-28 Omega Therapeutics, Inc. Compositions and methods for reducing cxcl9, cxcl10, and cxcl11 gene expression
WO2025129128A1 (en) 2023-12-15 2025-06-19 Vivasor, Inc. Compositions and methods for non-viral delivery of therapeutic compounds
WO2025133951A1 (en) 2023-12-21 2025-06-26 Genevant Sciences Gmbh Ionizable lipids suitable for lipid nanoparticles
WO2025166323A2 (en) 2024-02-02 2025-08-07 Editas Medicine, Inc. Crispr-related methods and compositions targeting lipoprotein (a) expression
WO2025213138A1 (en) 2024-04-05 2025-10-09 Editas Medicine, Inc. Crispr/rna-guided nuclease related methods and compositions for treating primary open angle glaucoma
WO2026022656A2 (en) 2024-07-22 2026-01-29 Genevant Sciences Gmbh Lipid particle formulations with permanently charged cationic lipids
WO2026022677A1 (en) 2024-07-22 2026-01-29 Genevant Sciences Gmbh Permanently charged cationic lipids

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US4618689A (en) 1985-07-18 1986-10-21 General Electric Company Novel aminofunctional silicone compositions
JPH08166679A (ja) * 1994-12-13 1996-06-25 Fuji Xerox Co Ltd 電子写真感光体およびのその製造方法
DE10058620A1 (de) * 2000-11-25 2002-05-29 Degussa Verfahren zur Herstellung von Aminoalkylsilanen
US7901708B2 (en) 2002-06-28 2011-03-08 Protiva Biotherapeutics, Inc. Liposomal apparatus and manufacturing methods
ES2559828T3 (es) 2003-07-16 2016-02-16 Protiva Biotherapeutics Inc. ARN de interferencia encapsulado en lípidos
WO2006113679A2 (en) * 2005-04-15 2006-10-26 Board Of Regents, The University Of Texas System Delivery of sirna by neutral lipid compositions
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ITMI20061766A1 (it) * 2006-09-15 2008-03-16 N P T S R L Prepolimeri silano-terminati e relativi formulati adesivo-sigillanti
AU2009238175C1 (en) 2008-04-15 2023-11-30 Arbutus Biopharma Corporation Novel lipid formulations for nucleic acid delivery
CN104119242B (zh) 2008-10-09 2017-07-07 泰米拉制药公司 改善的氨基脂质和递送核酸的方法
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