JP2022180384A5 - - Google Patents
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- JP2022180384A5 JP2022180384A5 JP2022135767A JP2022135767A JP2022180384A5 JP 2022180384 A5 JP2022180384 A5 JP 2022180384A5 JP 2022135767 A JP2022135767 A JP 2022135767A JP 2022135767 A JP2022135767 A JP 2022135767A JP 2022180384 A5 JP2022180384 A5 JP 2022180384A5
- Authority
- JP
- Japan
- Prior art keywords
- snv
- amount
- target
- sample
- targets
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000007523 nucleic acids Chemical class 0.000 claims 43
- 102000039446 nucleic acids Human genes 0.000 claims 43
- 108020004707 nucleic acids Proteins 0.000 claims 43
- 108700028369 Alleles Proteins 0.000 claims 33
- 238000000034 method Methods 0.000 claims 33
- 239000000523 sample Substances 0.000 claims 32
- 230000003321 amplification Effects 0.000 claims 12
- 238000003199 nucleic acid amplification method Methods 0.000 claims 12
- 239000000203 mixture Substances 0.000 claims 9
- 238000012207 quantitative assay Methods 0.000 claims 9
- 238000003556 assay Methods 0.000 claims 5
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 238000012544 monitoring process Methods 0.000 claims 2
- 238000003753 real-time PCR Methods 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 238000007847 digital PCR Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000001605 fetal effect Effects 0.000 claims 1
- 239000007850 fluorescent dye Substances 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662330053P | 2016-04-29 | 2016-04-29 | |
| US62/330,053 | 2016-04-29 | ||
| JP2018556983A JP7630902B2 (ja) | 2016-04-29 | 2017-04-29 | 多重／最適化ミスマッチ増幅（ｍｏｍａ）－標的数 |
| PCT/US2017/030293 WO2017190106A1 (en) | 2016-04-29 | 2017-04-29 | Multiplexed optimized mismatch amplification (moma)-target number |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018556983A Division JP7630902B2 (ja) | 2016-04-29 | 2017-04-29 | 多重／最適化ミスマッチ増幅（ｍｏｍａ）－標的数 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022180384A JP2022180384A (ja) | 2022-12-06 |
| JP2022180384A5 true JP2022180384A5 (enExample) | 2023-03-23 |
Family
ID=60161206
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018556983A Active JP7630902B2 (ja) | 2016-04-29 | 2017-04-29 | 多重／最適化ミスマッチ増幅（ｍｏｍａ）－標的数 |
| JP2022135767A Pending JP2022180384A (ja) | 2016-04-29 | 2022-08-29 | 多重／最適化ミスマッチ増幅（ｍｏｍａ）－標的数 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018556983A Active JP7630902B2 (ja) | 2016-04-29 | 2017-04-29 | 多重／最適化ミスマッチ増幅（ｍｏｍａ）－標的数 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20190153521A1 (enExample) |
| EP (2) | EP3449019B1 (enExample) |
| JP (2) | JP7630902B2 (enExample) |
| CN (1) | CN109661475A (enExample) |
| AU (1) | AU2017258801A1 (enExample) |
| BR (1) | BR112018072196A2 (enExample) |
| CA (1) | CA3022572A1 (enExample) |
| EA (1) | EA201892489A1 (enExample) |
| IL (1) | IL262642A (enExample) |
| MX (1) | MX2018013224A (enExample) |
| WO (1) | WO2017190106A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US10179937B2 (en) | 2014-04-21 | 2019-01-15 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| AU2011255641A1 (en) | 2010-05-18 | 2012-12-06 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| CA2821906C (en) | 2010-12-22 | 2020-08-25 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| CA2824387C (en) | 2011-02-09 | 2019-09-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| US20180173846A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| DK3294906T3 (en) | 2015-05-11 | 2024-08-05 | Natera Inc | Methods for determining ploidy |
| WO2017181202A2 (en) | 2016-04-15 | 2017-10-19 | Natera, Inc. | Methods for lung cancer detection |
| WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| CN110177874A (zh) * | 2016-11-02 | 2019-08-27 | 威斯康星州立大学医学院 | 用于使用错配扩增和统计方法来评估风险的方法 |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| US11773434B2 (en) | 2017-06-20 | 2023-10-03 | The Medical College Of Wisconsin, Inc. | Assessing transplant complication risk with total cell-free DNA |
| CA3085933A1 (en) | 2017-12-14 | 2019-06-20 | Tai Diagnostics, Inc. | Assessing graft suitability for transplantation |
| EP3781714B1 (en) | 2018-04-14 | 2026-01-07 | Natera, Inc. | Methods for cancer detection and monitoring by means of personalized detection of circulating tumor dna |
| WO2019217918A1 (en) * | 2018-05-10 | 2019-11-14 | The Medical College Of Wisconsin, Inc. | Multiplexed optimized mismatch amplification (moma)-cancer risk assessment with non-cancer associated targets |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| WO2020105058A1 (en) * | 2018-11-25 | 2020-05-28 | Azulay Chen | Methods for measuring small nucleic acid abundance differences |
| US11931674B2 (en) | 2019-04-04 | 2024-03-19 | Natera, Inc. | Materials and methods for processing blood samples |
| US12305235B2 (en) | 2019-06-06 | 2025-05-20 | Natera, Inc. | Methods for detecting immune cell DNA and monitoring immune system |
| US12023370B2 (en) * | 2021-04-08 | 2024-07-02 | Anticancer Inc. | Composition for the treatment of COVID-19 infection, and a method of treatment |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1599608A4 (en) * | 2003-03-05 | 2007-07-18 | Genetic Technologies Ltd | Identification of fetal DNA and fetal cell marker in maternal plasma or serum |
| JP5842811B2 (ja) | 2010-03-24 | 2016-01-13 | 凸版印刷株式会社 | 競合プライマーによる標的塩基配列の検出方法 |
| UA115321C2 (uk) * | 2011-12-16 | 2017-10-25 | Басф Агрокемікал Продактс Б.В. | Спосіб та комплект для аналізу ahasl генів у рослин |
| AU2013249012B2 (en) * | 2012-04-19 | 2019-03-28 | The Medical College Of Wisconsin, Inc. | Highly sensitive surveillance using detection of cell free DNA |
| US20140242582A1 (en) | 2013-02-28 | 2014-08-28 | Ariosa Diagnostics, Inc. | Detection of genetic abnormalities using ligation-based detection and digital pcr |
| WO2014143989A1 (en) * | 2013-03-15 | 2014-09-18 | Medical College Of Wisconsin, Inc. | Fetal well being surveillance using fetal specific cell free dna |
| LT3004388T (lt) | 2013-05-29 | 2019-01-25 | Chronix Biomedical | Donoro ne ląstelinės dnr aptikimas ir jos kiekio nustatymas organo transplantanto recipientų apytakoje |
| US20170051343A1 (en) * | 2014-02-14 | 2017-02-23 | The Board Of Regents Of The University Of Texas System | Strand exchange hairpin primers that give high allelic discrimination |
| MX2017013878A (es) * | 2015-04-30 | 2018-06-22 | Medical College Of Wisconsin Inc | Amplificación de discordancias optimizadas multiplicadas (moma) - reacción en cadena de polimerasa (pcr) en tiempo real, para evaluar el ácido desoxirribonucleico (adn) libre de celula. |
-
2017
- 2017-04-29 CA CA3022572A patent/CA3022572A1/en active Pending
- 2017-04-29 AU AU2017258801A patent/AU2017258801A1/en not_active Abandoned
- 2017-04-29 EA EA201892489A patent/EA201892489A1/ru unknown
- 2017-04-29 EP EP17790615.3A patent/EP3449019B1/en active Active
- 2017-04-29 EP EP23192474.7A patent/EP4306653A3/en not_active Withdrawn
- 2017-04-29 US US16/097,443 patent/US20190153521A1/en not_active Abandoned
- 2017-04-29 CN CN201780040673.1A patent/CN109661475A/zh active Pending
- 2017-04-29 WO PCT/US2017/030293 patent/WO2017190106A1/en not_active Ceased
- 2017-04-29 BR BR112018072196A patent/BR112018072196A2/pt not_active IP Right Cessation
- 2017-04-29 JP JP2018556983A patent/JP7630902B2/ja active Active
- 2017-04-29 MX MX2018013224A patent/MX2018013224A/es unknown
-
2018
- 2018-10-28 IL IL262642A patent/IL262642A/en unknown
-
2022
- 2022-08-29 JP JP2022135767A patent/JP2022180384A/ja active Pending
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