JP2022166217A5 - - Google Patents
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- Publication number
- JP2022166217A5 JP2022166217A5 JP2022130386A JP2022130386A JP2022166217A5 JP 2022166217 A5 JP2022166217 A5 JP 2022166217A5 JP 2022130386 A JP2022130386 A JP 2022130386A JP 2022130386 A JP2022130386 A JP 2022130386A JP 2022166217 A5 JP2022166217 A5 JP 2022166217A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- amount
- active agent
- carbopol
- levodopa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 38
- 239000013543 active substance Substances 0.000 claims 18
- 239000000203 mixture Substances 0.000 claims 18
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 claims 12
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 claims 12
- QTAOMKOIBXZKND-PPHPATTJSA-N carbidopa Chemical compound O.NN[C@@](C(O)=O)(C)CC1=CC=C(O)C(O)=C1 QTAOMKOIBXZKND-PPHPATTJSA-N 0.000 claims 12
- 229960004502 levodopa Drugs 0.000 claims 12
- 229920002125 Sokalan® Polymers 0.000 claims 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims 9
- 229960004205 carbidopa Drugs 0.000 claims 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 9
- 238000000034 method Methods 0.000 claims 6
- 239000002245 particle Substances 0.000 claims 6
- 239000003795 chemical substances by application Substances 0.000 claims 5
- 230000003472 neutralizing effect Effects 0.000 claims 5
- 239000002552 dosage form Substances 0.000 claims 4
- 239000007788 liquid Substances 0.000 claims 4
- 239000000375 suspending agent Substances 0.000 claims 4
- 239000002202 Polyethylene glycol Substances 0.000 claims 3
- 229920001223 polyethylene glycol Polymers 0.000 claims 3
- 229920000642 polymer Polymers 0.000 claims 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 2
- 239000006185 dispersion Substances 0.000 claims 2
- 239000001301 oxygen Substances 0.000 claims 2
- 229910052760 oxygen Inorganic materials 0.000 claims 2
- 239000002002 slurry Substances 0.000 claims 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 1
- 229940123973 Oxygen scavenger Drugs 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 230000004888 barrier function Effects 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000007789 gas Substances 0.000 claims 1
- 239000012535 impurity Substances 0.000 claims 1
- 238000001802 infusion Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024173125A JP2025000924A (ja) | 2016-07-20 | 2024-10-02 | レボドパ及びカルビドパ腸管ゲル、並びに使用方法 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662364770P | 2016-07-20 | 2016-07-20 | |
| US62/364,770 | 2016-07-20 | ||
| JP2019502047A JP2019523249A (ja) | 2016-07-20 | 2017-07-20 | レボドパ及びカルビドパ腸管ゲル、並びに使用方法 |
| PCT/US2017/043103 WO2018017850A1 (en) | 2016-07-20 | 2017-07-20 | Levodopa and carbidopa intestinal gel and methods of use |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019502047A Division JP2019523249A (ja) | 2016-07-20 | 2017-07-20 | レボドパ及びカルビドパ腸管ゲル、並びに使用方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024173125A Division JP2025000924A (ja) | 2016-07-20 | 2024-10-02 | レボドパ及びカルビドパ腸管ゲル、並びに使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022166217A JP2022166217A (ja) | 2022-11-01 |
| JP2022166217A5 true JP2022166217A5 (https=) | 2023-06-13 |
Family
ID=59506369
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019502047A Pending JP2019523249A (ja) | 2016-07-20 | 2017-07-20 | レボドパ及びカルビドパ腸管ゲル、並びに使用方法 |
| JP2022130386A Ceased JP2022166217A (ja) | 2016-07-20 | 2022-08-18 | レボドパ及びカルビドパ腸管ゲル、並びに使用方法 |
| JP2024173125A Pending JP2025000924A (ja) | 2016-07-20 | 2024-10-02 | レボドパ及びカルビドパ腸管ゲル、並びに使用方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019502047A Pending JP2019523249A (ja) | 2016-07-20 | 2017-07-20 | レボドパ及びカルビドパ腸管ゲル、並びに使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024173125A Pending JP2025000924A (ja) | 2016-07-20 | 2024-10-02 | レボドパ及びカルビドパ腸管ゲル、並びに使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US20180021280A1 (https=) |
| EP (1) | EP3487479A1 (https=) |
| JP (3) | JP2019523249A (https=) |
| CN (1) | CN109715139A (https=) |
| AU (2) | AU2017299710A1 (https=) |
| BR (1) | BR112019001082A2 (https=) |
| CA (1) | CA3031254A1 (https=) |
| MX (2) | MX2019000849A (https=) |
| WO (1) | WO2018017850A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016258179B2 (en) | 2015-05-06 | 2021-07-01 | Synagile Corporation | Pharmaceutical suspensions containing drug particles, devices for their administration, and methods of their use |
| US11844860B2 (en) | 2018-03-02 | 2023-12-19 | Chiesi Farmaceutici S.P.A. | Pharmaceutical formulation for intraduodenal administration comprising melevodopa and carbidopa |
| WO2021039084A1 (ja) * | 2019-08-30 | 2021-03-04 | テルモ株式会社 | 注射液製剤 |
| EP4616878A1 (en) * | 2024-03-15 | 2025-09-17 | Cosmo Technologies Ltd. | Cannula for rectal administration of an enema and compositions for use therewith |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5831210B2 (ja) * | 1973-04-09 | 1983-07-05 | 武田薬品工業株式会社 | アンテイナスイセイケンダクエキノセイゾウホウ |
| SE9203594D0 (sv) * | 1992-11-30 | 1992-11-30 | Christer Nystroem | Laekemedel i dispersa system |
| US6071523A (en) * | 1998-06-03 | 2000-06-06 | Taro Pharmaceuticals Industries, Ltd. | Spill resistant pharmaceutical compositions in semi-solid form |
| CN1901881A (zh) * | 2003-10-31 | 2007-01-24 | 阿尔扎公司 | 用于增强的吸收的组合物和剂型 |
| RU2484815C2 (ru) * | 2006-05-31 | 2013-06-20 | Зольвай Фармасьютиклз Гмбх | Продолжительное 24-часовое введение в кишечник леводопа/карбидопа |
| DE102006034346B4 (de) * | 2006-07-25 | 2008-11-27 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren und Vorrichtung zum periodischen Messen der Fließgrenze von Dispersionen sowie deren Verwendung |
| US20150182688A1 (en) * | 2013-12-31 | 2015-07-02 | Abbvie Inc. | Devices and methods for delivering a beneficial agent to a user |
| SE538425C2 (en) * | 2014-09-04 | 2016-06-21 | Lobsor Pharmaceuticals Ab | Pharmaceutical compositions comprising levodopa, carbidopa and a comt inhibitor and method of administration thereof |
| PT3782617T (pt) * | 2014-09-04 | 2024-02-29 | Lobsor Pharmaceuticals Ab | Composições farmacêuticas de gel compreendendo levodopa, carbidopa e entacapona |
| MA41377A (fr) * | 2015-01-20 | 2017-11-28 | Abbvie Inc | Gel intestinal de lévodopa et de carbidona et procédés d'utilisation |
-
2017
- 2017-07-20 WO PCT/US2017/043103 patent/WO2018017850A1/en not_active Ceased
- 2017-07-20 JP JP2019502047A patent/JP2019523249A/ja active Pending
- 2017-07-20 AU AU2017299710A patent/AU2017299710A1/en not_active Abandoned
- 2017-07-20 CA CA3031254A patent/CA3031254A1/en not_active Abandoned
- 2017-07-20 MX MX2019000849A patent/MX2019000849A/es unknown
- 2017-07-20 CN CN201780056836.5A patent/CN109715139A/zh active Pending
- 2017-07-20 EP EP17746596.0A patent/EP3487479A1/en active Pending
- 2017-07-20 BR BR112019001082-3A patent/BR112019001082A2/pt not_active Application Discontinuation
- 2017-07-20 US US15/655,078 patent/US20180021280A1/en not_active Abandoned
-
2019
- 2019-01-18 MX MX2022014577A patent/MX2022014577A/es unknown
-
2020
- 2020-04-21 US US16/854,079 patent/US20210059968A1/en not_active Abandoned
-
2022
- 2022-08-03 US US17/817,191 patent/US20230129413A1/en not_active Abandoned
- 2022-08-18 JP JP2022130386A patent/JP2022166217A/ja not_active Ceased
-
2023
- 2023-05-29 AU AU2023203340A patent/AU2023203340A1/en not_active Abandoned
-
2024
- 2024-10-02 JP JP2024173125A patent/JP2025000924A/ja active Pending
-
2025
- 2025-09-19 US US19/334,420 patent/US20260014108A1/en active Pending
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