JP2022160401A5 - - Google Patents
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- Publication number
- JP2022160401A5 JP2022160401A5 JP2022104300A JP2022104300A JP2022160401A5 JP 2022160401 A5 JP2022160401 A5 JP 2022160401A5 JP 2022104300 A JP2022104300 A JP 2022104300A JP 2022104300 A JP2022104300 A JP 2022104300A JP 2022160401 A5 JP2022160401 A5 JP 2022160401A5
- Authority
- JP
- Japan
- Prior art keywords
- arenavirus
- vector
- infectious
- replication
- segment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000712891 Arenavirus Species 0.000 claims 135
- 239000013598 vector Substances 0.000 claims 95
- 208000015181 infectious disease Diseases 0.000 claims 56
- 230000002458 infectious effect Effects 0.000 claims 50
- 239000013603 viral vector Substances 0.000 claims 21
- 108020005345 3' Untranslated Regions Proteins 0.000 claims 16
- 125000003275 alpha amino acid group Chemical group 0.000 claims 16
- 108020003589 5' Untranslated Regions Proteins 0.000 claims 12
- 230000010076 replication Effects 0.000 claims 12
- 229920001184 polypeptide Polymers 0.000 claims 10
- 102000004196 processed proteins & peptides Human genes 0.000 claims 10
- 108090000765 processed proteins & peptides Proteins 0.000 claims 10
- 241000712910 Pichinde mammarenavirus Species 0.000 claims 8
- 238000000034 method Methods 0.000 claims 8
- 239000002773 nucleotide Substances 0.000 claims 8
- 125000003729 nucleotide group Chemical group 0.000 claims 8
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 229960005486 vaccine Drugs 0.000 claims 8
- 241000700605 Viruses Species 0.000 claims 6
- 101001065501 Escherichia phage MS2 Lysis protein Proteins 0.000 claims 4
- 241000712890 Junin mammarenavirus Species 0.000 claims 4
- 241000712899 Lymphocytic choriomeningitis mammarenavirus Species 0.000 claims 4
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 230000001568 sexual effect Effects 0.000 claims 2
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562173805P | 2015-06-10 | 2015-06-10 | |
| US62/173,805 | 2015-06-10 | ||
| US201562254410P | 2015-11-12 | 2015-11-12 | |
| US62/254,410 | 2015-11-12 | ||
| US201662331158P | 2016-05-03 | 2016-05-03 | |
| US62/331,158 | 2016-05-03 | ||
| PCT/EP2016/063182 WO2016198531A2 (en) | 2015-06-10 | 2016-06-09 | Hpv vaccines |
| JP2017563914A JP7098330B2 (ja) | 2015-06-10 | 2016-06-09 | Ｈｐｖワクチン |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017563914A Division JP7098330B2 (ja) | 2015-06-10 | 2016-06-09 | Ｈｐｖワクチン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022160401A JP2022160401A (ja) | 2022-10-19 |
| JP2022160401A5 true JP2022160401A5 (https=) | 2023-03-03 |
Family
ID=56137292
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017563914A Active JP7098330B2 (ja) | 2015-06-10 | 2016-06-09 | Ｈｐｖワクチン |
| JP2022104300A Pending JP2022160401A (ja) | 2015-06-10 | 2022-06-29 | Ｈｐｖワクチン |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017563914A Active JP7098330B2 (ja) | 2015-06-10 | 2016-06-09 | Ｈｐｖワクチン |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US10669315B2 (https=) |
| EP (1) | EP3307308A2 (https=) |
| JP (2) | JP7098330B2 (https=) |
| CN (2) | CN115197965A (https=) |
| AU (2) | AU2016274655B2 (https=) |
| CA (1) | CA2987155A1 (https=) |
| HK (1) | HK1246183A1 (https=) |
| WO (1) | WO2016198531A2 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2604695B1 (en) | 2007-12-27 | 2022-11-16 | Universität Zürich | Replication-defective arenavirus vectors |
| US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
| CN115058452A (zh) | 2013-12-03 | 2022-09-16 | 霍欧奇帕生物科技有限公司 | Cmv疫苗 |
| LT3218504T (lt) | 2014-11-13 | 2020-09-10 | Université De Geneve | Trijų segmentų arenavirusai kaip vakcinos vektoriai |
| EP3307308A2 (en) | 2015-06-10 | 2018-04-18 | Hookipa Biotech AG | Hpv vaccines |
| US20180289792A1 (en) | 2015-10-22 | 2018-10-11 | ModernaTX. Inc. | Sexually transmitted disease vaccines |
| IL314371A (en) | 2015-11-04 | 2024-09-01 | Hookipa Biotech Gmbh | Vaccines against hepatitis B virus |
| RS63546B1 (sr) | 2015-11-12 | 2022-09-30 | Hookipa Biotech Gmbh | Čestice arenavirusa kao vakcine protiv kancera |
| EP3518966A1 (en) | 2016-09-29 | 2019-08-07 | GlaxoSmithKline Biologicals S.A. | Compositions and methods of treatment of persistent hpv infection |
| EP3534943A2 (en) * | 2016-11-04 | 2019-09-11 | Hookipa Biotech GmbH | Replication-deficient arenavirus particles and tri-segmented arenavirus particles as cancer vaccines |
| AU2018247958A1 (en) * | 2017-04-07 | 2019-10-10 | Hookipa Biotech Gmbh | Arenavirus particles to treat solid tumors |
| AU2018301701A1 (en) * | 2017-07-14 | 2020-02-27 | Elevatebio Technologies, Inc. | Encapsulated polynucleotides and methods of use |
| EP3461497A1 (en) * | 2017-09-27 | 2019-04-03 | GlaxoSmithKline Biologicals S.A. | Viral antigens |
| EA202091513A1 (ru) | 2017-12-19 | 2020-09-09 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Вакцины против вируса гепатита b (hbv) и их применение |
| WO2019151760A1 (ko) * | 2018-02-02 | 2019-08-08 | 주식회사 에스엘백시젠 | 신규 다가 hpv 백신 조성물 |
| CN108424925A (zh) * | 2018-03-07 | 2018-08-21 | 江苏润洁生物科技有限公司 | 一种治疗性hpv核酸疫苗 |
| EP3880812A4 (en) * | 2018-11-13 | 2022-09-07 | Oncorus, Inc. | ENCAPSULATED POLYNUCLEOTIDES AND METHODS OF USE |
| CN113347987A (zh) * | 2018-11-28 | 2021-09-03 | 总医院公司 | 针对共生病毒的t细胞导向的抗癌疫苗 |
| JP7125760B2 (ja) * | 2019-06-14 | 2022-08-25 | 国立研究開発法人理化学研究所 | 免疫系を賦活化する細胞および当該細胞を含む医薬組成物 |
| AU2020297011A1 (en) * | 2019-06-18 | 2022-02-10 | Janssen Sciences Ireland Unlimited Company | Arenavirus vectors for hepatitis B virus (HBV) vaccines and uses thereof |
| JP7783631B2 (ja) * | 2019-11-07 | 2025-12-10 | ウニヴェルズィテート バーゼル | ベクターとしてのアレナウイルス |
| IL292989A (en) * | 2019-11-15 | 2022-07-01 | Daiichi Sankyo Co Ltd | Nucleic acid lipid particle vaccine enveloping human papillomavirus mrna |
| PH12022553102A1 (en) * | 2020-05-14 | 2023-11-20 | Inovio Pharmaceuticals Inc | Vaccines for recurrent respiratory papillomatosis and methods of using the same |
| MX2022014725A (es) | 2020-05-29 | 2023-02-09 | Hookipa Biotech Gmbh | Estrategias de tratamiento del cáncer mediante el uso de vectores de arenavirus. |
| CN117280027A (zh) | 2021-03-23 | 2023-12-22 | 霍欧奇帕生物科技有限公司 | 用于治疗前列腺癌的沙粒病毒 |
| CN115820696A (zh) * | 2022-07-28 | 2023-03-21 | 怡道生物科技(苏州)有限公司 | 治疗性多价HPV mRNA疫苗及其制备方法 |
| AU2024343172A1 (en) | 2023-09-15 | 2026-03-05 | Gilead Sciences, Inc. | Arenavirus formulations, methods and uses thereof |
| WO2025155938A1 (en) * | 2024-01-18 | 2025-07-24 | Aov Biopharma, Inc. | Vaccine for prevention and treatment of human papilloma virus related cancer |
| WO2025191169A1 (en) * | 2024-03-15 | 2025-09-18 | Hookipa Biotech Gmbh | Modified arenavirus particles expressing cancer testis antigens as cancer immunotherapies |
| CN118344491B (zh) * | 2024-05-03 | 2025-02-14 | 华中科技大学同济医学院附属同济医院 | 一种hpv16/18治疗性疫苗、制备方法和应用 |
| CN118599010B (zh) * | 2024-05-03 | 2025-06-27 | 武汉凯德基诺生物技术有限公司 | 一种hpv16/18/52治疗性疫苗、制备方法和应用 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US6869779B1 (en) * | 1998-08-27 | 2005-03-22 | Fuso Pharmaceutical Industries, Ltd. | Nucleic acid sequence for potentiating the expression of useful gene and method therefor |
| EP1820853B1 (en) * | 1999-04-06 | 2011-09-21 | Wisconsin Alumni Research Foundation | Recombinant influenza viruses for vaccines and gene therapy |
| MXPA05003395A (es) * | 2002-10-03 | 2005-06-22 | Wyeth Corp | Polipeptidos de virus de papiloma humano y composiciones inmunogenas. |
| WO2006060257A2 (en) * | 2004-11-30 | 2006-06-08 | Aeras Global Tb Vaccine Foundation | Bacterial packaging strains usefuel for generation and production of recombinant double-stranded rna nucleocapsids and uses thereof |
| CA2646539A1 (en) | 2006-03-23 | 2007-09-27 | Novartis Ag | Imidazoquinoxaline compounds as immunomodulators |
| CA2646891A1 (en) | 2006-03-23 | 2007-09-27 | Novartis Ag | Immunopotentiating compounds |
| EP2604695B1 (en) | 2007-12-27 | 2022-11-16 | Universität Zürich | Replication-defective arenavirus vectors |
| CN102002105B (zh) * | 2009-09-03 | 2013-01-23 | 中国疾病预防控制中心病毒病预防控制所 | Hpv 16型e7e6融合蛋白基因、表达载体、方法、细胞和用途 |
| WO2012162428A1 (en) * | 2011-05-23 | 2012-11-29 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Prime-boost vaccination for viral infection |
| ES2646590T3 (es) | 2012-01-24 | 2017-12-14 | Sanford Health | Polinucleótidos para el tratamiento de tumores positivos para polipéptidos víricos oncogénicos |
| EP2834356A4 (en) * | 2012-04-02 | 2015-09-02 | Univ Arizona | RECOMBINANT BACTERIUM FOR INDUCING A CELLULAR IMMUNE RESPONSE |
| US8999925B2 (en) * | 2013-02-26 | 2015-04-07 | The Administrators Of The Tulane Educational Fund | Arenavirus inhibiting peptides and uses therefor |
| EP2968506B1 (en) | 2013-03-15 | 2019-07-31 | Université de Genève | Anti-mycobacterial vaccines |
| GB201305361D0 (en) | 2013-03-25 | 2013-05-08 | Univ Edinburgh | Enhanced expression |
| CN115058452A (zh) | 2013-12-03 | 2022-09-16 | 霍欧奇帕生物科技有限公司 | Cmv疫苗 |
| US10342861B2 (en) | 2014-05-27 | 2019-07-09 | University Of Rochester | Arenavirus vaccine |
| US9943585B2 (en) | 2014-07-30 | 2018-04-17 | University Of Rochester | Methods and compositions related to reorganization of arenavirus genome for development of novel arenavirus live-attenuated vaccines (LAV) |
| PL3198008T3 (pl) | 2014-09-22 | 2020-03-31 | Regents Of The University Of Minnesota | Układ wykorzystujący odwrotną genetykę wirusa pichinde i sposoby zastosowania |
| GB201419572D0 (en) | 2014-11-03 | 2014-12-17 | Pirbright Inst The | Virus |
| LT3218504T (lt) | 2014-11-13 | 2020-09-10 | Université De Geneve | Trijų segmentų arenavirusai kaip vakcinos vektoriai |
| DE102015207036A1 (de) | 2015-04-17 | 2016-10-20 | Karl Sebastian Lang | Arenaviren zur Anwendung bei der Behandlung und/oder Vorbeugung von Tumoren sowie Verfahren zur Herstellung von Arenaviren mit (verbesserten) tumorregressiven Eigenschaften |
| EP3307308A2 (en) | 2015-06-10 | 2018-04-18 | Hookipa Biotech AG | Hpv vaccines |
| EP3365005B1 (en) | 2015-10-23 | 2025-04-09 | Institut Pasteur | Recombinant mopeia virus and vaccine platform |
| IL314371A (en) | 2015-11-04 | 2024-09-01 | Hookipa Biotech Gmbh | Vaccines against hepatitis B virus |
| RS63546B1 (sr) | 2015-11-12 | 2022-09-30 | Hookipa Biotech Gmbh | Čestice arenavirusa kao vakcine protiv kancera |
| US10980877B2 (en) | 2016-04-28 | 2021-04-20 | The University Of Chicago | Method for treating melanoma using lymphangiogenesis inducers and a melanoma-specific antigen |
| US20190135875A1 (en) | 2016-05-18 | 2019-05-09 | Hookipa Biotech Gmbh | Tri-segmented pichinde viruses as vaccine vectors |
| EP3534943A2 (en) | 2016-11-04 | 2019-09-11 | Hookipa Biotech GmbH | Replication-deficient arenavirus particles and tri-segmented arenavirus particles as cancer vaccines |
| AU2018247958A1 (en) | 2017-04-07 | 2019-10-10 | Hookipa Biotech Gmbh | Arenavirus particles to treat solid tumors |
| AU2020297011A1 (en) * | 2019-06-18 | 2022-02-10 | Janssen Sciences Ireland Unlimited Company | Arenavirus vectors for hepatitis B virus (HBV) vaccines and uses thereof |
| JP7783631B2 (ja) | 2019-11-07 | 2025-12-10 | ウニヴェルズィテート バーゼル | ベクターとしてのアレナウイルス |
| MX2022014725A (es) | 2020-05-29 | 2023-02-09 | Hookipa Biotech Gmbh | Estrategias de tratamiento del cáncer mediante el uso de vectores de arenavirus. |
-
2016
- 2016-06-09 EP EP16730302.3A patent/EP3307308A2/en active Pending
- 2016-06-09 WO PCT/EP2016/063182 patent/WO2016198531A2/en not_active Ceased
- 2016-06-09 JP JP2017563914A patent/JP7098330B2/ja active Active
- 2016-06-09 HK HK18105733.1A patent/HK1246183A1/zh unknown
- 2016-06-09 CN CN202210614772.9A patent/CN115197965A/zh active Pending
- 2016-06-09 AU AU2016274655A patent/AU2016274655B2/en active Active
- 2016-06-09 CA CA2987155A patent/CA2987155A1/en active Pending
- 2016-06-09 CN CN201680046208.4A patent/CN107921117B/zh active Active
- 2016-06-09 US US15/580,964 patent/US10669315B2/en active Active
-
2020
- 2020-04-30 US US16/863,456 patent/US11407790B2/en active Active
-
2021
- 2021-09-13 AU AU2021232660A patent/AU2021232660B2/en active Active
-
2022
- 2022-06-29 US US17/853,783 patent/US20230086859A1/en not_active Abandoned
- 2022-06-29 JP JP2022104300A patent/JP2022160401A/ja active Pending
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