JP2022153638A5 - - Google Patents
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- Publication number
- JP2022153638A5 JP2022153638A5 JP2022124557A JP2022124557A JP2022153638A5 JP 2022153638 A5 JP2022153638 A5 JP 2022153638A5 JP 2022124557 A JP2022124557 A JP 2022124557A JP 2022124557 A JP2022124557 A JP 2022124557A JP 2022153638 A5 JP2022153638 A5 JP 2022153638A5
- Authority
- JP
- Japan
- Prior art keywords
- dosage form
- bupropion
- disorders include
- humans
- administered
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002552 dosage form Substances 0.000 claims 23
- SNPPWIUOZRMYNY-VIFPVBQESA-N (S)-bupropion Chemical compound CC(C)(C)N[C@@H](C)C(=O)C1=CC=CC(Cl)=C1 SNPPWIUOZRMYNY-VIFPVBQESA-N 0.000 claims 7
- 208000015114 central nervous system disease Diseases 0.000 claims 6
- 241000282412 Homo Species 0.000 claims 5
- 229960001058 bupropion Drugs 0.000 claims 4
- SNPPWIUOZRMYNY-UHFFFAOYSA-N bupropion Chemical compound CC(C)(C)NC(C)C(=O)C1=CC=CC(Cl)=C1 SNPPWIUOZRMYNY-UHFFFAOYSA-N 0.000 claims 3
- RCOBKSKAZMVBHT-RNCFNFMXSA-N (2r,3r)-2-(3-chlorophenyl)-3,5,5-trimethylmorpholin-2-ol Chemical compound C[C@H]1NC(C)(C)CO[C@]1(O)C1=CC=CC(Cl)=C1 RCOBKSKAZMVBHT-RNCFNFMXSA-N 0.000 claims 2
- 239000013543 active substance Substances 0.000 claims 2
- 210000003169 central nervous system Anatomy 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 208000007848 Alcoholism Diseases 0.000 claims 1
- 208000036864 Attention deficit/hyperactivity disease Diseases 0.000 claims 1
- YZCKVEUIGOORGS-OUBTZVSYSA-N Deuterium Chemical compound [2H] YZCKVEUIGOORGS-OUBTZVSYSA-N 0.000 claims 1
- 206010057852 Nicotine dependence Diseases 0.000 claims 1
- 208000025569 Tobacco Use disease Diseases 0.000 claims 1
- 208000028552 Treatment-Resistant Depressive disease Diseases 0.000 claims 1
- 201000007930 alcohol dependence Diseases 0.000 claims 1
- 208000015802 attention deficit-hyperactivity disease Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229910052805 deuterium Inorganic materials 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862634718P | 2018-02-23 | 2018-02-23 | |
| US62/634,718 | 2018-02-23 | ||
| US201962794469P | 2019-01-18 | 2019-01-18 | |
| US62/794,469 | 2019-01-18 | ||
| US201962809480P | 2019-02-22 | 2019-02-22 | |
| US62/809,480 | 2019-02-22 | ||
| JP2020544420A JP2021513998A (ja) | 2018-02-23 | 2019-02-25 | 鏡像異性体的に濃縮された、または鏡像異性体的に純粋なブプロピオンの剤形 |
| PCT/US2019/019445 WO2019165379A1 (en) | 2018-02-23 | 2019-02-25 | Dosage forms and methods for enantiomerically enriched or pure bupropion |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020544420A Division JP2021513998A (ja) | 2018-02-23 | 2019-02-25 | 鏡像異性体的に濃縮された、または鏡像異性体的に純粋なブプロピオンの剤形 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022153638A JP2022153638A (ja) | 2022-10-12 |
| JP2022153638A5 true JP2022153638A5 (enrdf_load_stackoverflow) | 2022-12-02 |
Family
ID=67688503
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020544420A Pending JP2021513998A (ja) | 2018-02-23 | 2019-02-25 | 鏡像異性体的に濃縮された、または鏡像異性体的に純粋なブプロピオンの剤形 |
| JP2022124557A Pending JP2022153638A (ja) | 2018-02-23 | 2022-08-04 | 鏡像異性体的に濃縮された、または鏡像異性体的に純粋なブプロピオンの剤形および方法 |
| JP2024041381A Pending JP2024075655A (ja) | 2018-02-23 | 2024-03-15 | 鏡像異性体的に濃縮された、または鏡像異性体的に純粋なブプロピオンの剤形および方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020544420A Pending JP2021513998A (ja) | 2018-02-23 | 2019-02-25 | 鏡像異性体的に濃縮された、または鏡像異性体的に純粋なブプロピオンの剤形 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024041381A Pending JP2024075655A (ja) | 2018-02-23 | 2024-03-15 | 鏡像異性体的に濃縮された、または鏡像異性体的に純粋なブプロピオンの剤形および方法 |
Country Status (19)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL313368A (en) * | 2018-02-23 | 2024-08-01 | Axsome Therapeutics Inc | Dosage forms and methods for enantiomerically enriched or pure bupropion |
| US11660273B2 (en) | 2018-09-20 | 2023-05-30 | Axsome Therapeutics, Inc. | Dosage forms and methods for enantiomerically enriched or pure bupropion |
| US11291639B2 (en) | 2018-09-20 | 2022-04-05 | Axsome Therapeutics, Inc. | Dosage forms and methods for enantiomerically enriched or pure bupropion |
| US11660274B2 (en) | 2018-09-20 | 2023-05-30 | Axsome Therapeutics, Inc. | Dosage forms and methods for enantiomerically enriched or pure bupropion |
| WO2021055124A1 (en) * | 2019-09-20 | 2021-03-25 | Axsome Therapeutics, Inc. | Dosage forms and methods for enantiomerically enriched or pure bupropion |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2318960A1 (en) * | 1998-01-29 | 1999-08-05 | Sepracor Inc. | Pharmaceutical uses of optically pure (+)-bupropion |
| US6337328B1 (en) * | 1999-03-01 | 2002-01-08 | Sepracor, Inc. | Bupropion metabolites and methods of use |
| DE60330909D1 (de) * | 2003-08-08 | 2010-02-25 | Biovail Lab Int Srl | Tablette mit modifizierter freisetzung von bupropion hydrochlorid |
| WO2012118562A1 (en) * | 2011-03-02 | 2012-09-07 | Rhine Pharmaceuticals, Llc | Compositions and methods for treating depression, adhd and other central nervous system disorders employing novel bupropion compounds, and methods for production and use of novel bupropion compounds and formulations |
| US10080727B2 (en) * | 2013-11-05 | 2018-09-25 | Antecip Bioventures Ii Llc | Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic effects |
| US9474731B1 (en) * | 2013-11-05 | 2016-10-25 | Antecip Bioventures Ii Llc | Compositions and methods for increasing the metabolic lifetime of dextromethorphan and related pharmacodynamic effects |
| US9198905B2 (en) * | 2013-11-05 | 2015-12-01 | Antecip Bioventures Ii Llc | Compositions and methods for reducing dextrorphan plasma levels and related pharmacodynamic effects |
| WO2015095713A1 (en) * | 2013-12-20 | 2015-06-25 | Deuterx, Llc | Methods of treating neurological and other disorders using enantiopure deuterium-enriched bupropion |
| IL313368A (en) * | 2018-02-23 | 2024-08-01 | Axsome Therapeutics Inc | Dosage forms and methods for enantiomerically enriched or pure bupropion |
-
2019
- 2019-02-25 IL IL313368A patent/IL313368A/en unknown
- 2019-02-25 BR BR112020017179-4A patent/BR112020017179A2/pt unknown
- 2019-02-25 CA CA3092076A patent/CA3092076A1/en active Pending
- 2019-02-25 PE PE2020001272A patent/PE20211752A1/es unknown
- 2019-02-25 KR KR1020237017449A patent/KR20230075531A/ko not_active Ceased
- 2019-02-25 MA MA051914A patent/MA51914A/fr unknown
- 2019-02-25 SG SG11202008056SA patent/SG11202008056SA/en unknown
- 2019-02-25 CR CR20200415A patent/CR20200415A/es unknown
- 2019-02-25 WO PCT/US2019/019445 patent/WO2019165379A1/en not_active Application Discontinuation
- 2019-02-25 MY MYPI2020004315A patent/MY202993A/en unknown
- 2019-02-25 KR KR1020247017593A patent/KR20240091043A/ko active Pending
- 2019-02-25 IL IL276871A patent/IL276871B2/en unknown
- 2019-02-25 EP EP19756920.5A patent/EP3755312A4/en active Pending
- 2019-02-25 KR KR1020207027256A patent/KR20210003091A/ko not_active Ceased
- 2019-02-25 JP JP2020544420A patent/JP2021513998A/ja active Pending
- 2019-02-25 NZ NZ767378A patent/NZ767378A/en unknown
- 2019-02-25 CN CN201980026874.5A patent/CN112087999A/zh active Pending
- 2019-02-25 AU AU2019223187A patent/AU2019223187B2/en active Active
- 2019-02-25 MX MX2020008704A patent/MX2020008704A/es unknown
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2020
- 2020-08-20 MX MX2023009281A patent/MX2023009281A/es unknown
- 2020-08-21 NI NI202000056A patent/NI202000056A/es unknown
- 2020-08-21 CL CL2020002166A patent/CL2020002166A1/es unknown
- 2020-09-23 EC ECSENADI202060179A patent/ECSP20060179A/es unknown
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2022
- 2022-06-27 AU AU2022204521A patent/AU2022204521B2/en active Active
- 2022-08-04 JP JP2022124557A patent/JP2022153638A/ja active Pending
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2024
- 2024-03-15 JP JP2024041381A patent/JP2024075655A/ja active Pending
- 2024-08-17 AU AU2024205858A patent/AU2024205858A1/en active Pending