JP2022140453A - Composition for removing undesired molecules - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a method of producing a composition for removing undesired molecules to which highly branched cyclic dextrin is applied.

SOLUTION: The problem is solved by a method of producing highly branched cyclic dextrin whose internal space contains a perfume, the method comprising introducing highly branched cyclic dextrin (HBCD) or a derivative thereof and a hydrophobic perfume with ClogP greater than or equal to 3 into a solvent and mixing them.

SELECTED DRAWING: Figure 1

COPYRIGHT: (C)2022,JPO&INPIT

Description

The present invention relates to compositions capable of removing unwanted molecules and delivering perfume substances.

This application is based on Korean Patent Application No. 10-2014-0050740 filed on April 28, 2014, Korean Patent Application No. 10-2014-0087656 filed on July 11, 2014, and filed on January 7, 2015. Claiming priority based on Korean Patent Application No. 10-2015-0002127, all contents disclosed in the specification and drawings of that application are incorporated herein by reference.

There are various sources of offensive odors generated in general living spaces. Many malodors are composites of various components, mainly sulfur-based or nitrogen-based. Methods for removing such malodor include physical, chemical, biological or sensory methods. A physical method means a method using adsorption by a porous substance such as activated carbon, silica gel, zeolite, alumina or ceramics, or absorption by a surfactant or the like. Chemical methods deodorize substances that are highly reactive to malodorous components or substances that react with malodorous components to form complexes using neutralization reactions, condensation reactions, addition reactions, oxidation or reduction reactions, etc. It refers to a method of deodorizing bad odors by using it as an agent. The biological method means a method of deodorizing by using a surfactant, ethylene glycol, microorganisms, enzymes, or the like to sterilize germs or bacteria that cause offensive odors or prevent putrefaction. A sensory deodorizing method refers to a method of replacing or neutralizing malodorous stimulation with an aromatic substance such as a perfume. In addition to these methods, various techniques for removing bad odors are known, but there is still a lack of techniques that can continuously remove bad odors.

In response to the many demands for removal of odors from clothes, living spaces, and limited indoor spaces, companies are developing laundry detergents, softeners, surface cleaners, kitchen detergents, deodorants, shampoos, hair conditioners, body care products, and more. The above purpose has been achieved through various researches on its application to armpit deodorants and the like. An example of an effective scavenging agent in many studies is the application of cyclodextrin (US Pat. No. 6,878,695). The cyclodextrin is a polysaccharide having a cyclic structure in which 6 to 12 glucose units are linked by α-1,4 bonds. As an example of the most developed and applied cyclodextrins, α-cyclodextrin contains 6 glucoses, as another example, β-cyclodextrin contains 7 glucoses, and as yet another example, γ-cyclodextrin contains 8 glucoses. containing one glucose, all of which have a donut-shaped ring structure.

The specific bonding and structure between glucoses causes the cyclodextrin to have a rigid conical structure with a specific volume of space. Each interior space "array" is formed by oxygen atoms in glycoside bridges with hydrogen atoms. Therefore, the inner surface has a very high hydrophobicity, and the specific shape and physicochemical properties of the interior are organic molecules or parts of organic molecules that conform to the shape of the interior space of cyclodextrin or its derivatives. have structural features that can absorb Therefore, when a formulation containing cyclodextrin is applied to the surface of an object, foreign substances such as offensive odors are included in the internal space of the cyclodextrin, thereby making it possible to remove offensive odors. In addition, by impregnating a portion of the product with perfume during the manufacturing process, it is possible to maintain the fragrance during use.

However, such a cyclodextrin has the disadvantage that the size of the internal space is constant, so the fragrant substance and off-flavour substance that can be included are limited. When it is included, there is a limit to the expression of efficacy due to the low solubility of cyclodextrin. In particular, a perfume substance having a ClogP of 3 or higher and a boiling point of 250° C. or higher, which is generally known to have excellent lingering properties and a good offensive odor masking effect, is used to remove offensive odor substances by cyclodextrin. Problems have been encountered in that the removal and delivery of perfume substances are limited. In addition, since cyclodextrin has low solubility, derivatives are being developed to overcome this problem. is substituted with a methyl group or an ethyl group, or is substituted with a hydropropyl group in which R is a -CH ₂ -CH(OH)-CH ₃ or -CH ₂ CH ₂ -OH group , cationic cyclodextrins that are cationic at pH.

The present invention relates to the removal of undesirable molecules, and more particularly, it overcomes the above-mentioned problems of cyclodextrin, which has been conventionally used for the removal of offensive odors, and can include more diverse kinds of fragrance substances and offensive odor substances. Regarding matter.

The present invention has been made in view of the above problems, and by applying a cyclic dextrin having a wider and variously sized internal space, a wider variety of undesirable Molecules, more specifically, not only to facilitate the removal of various sources of offensive odors, but also to make it possible to clathrate more diverse, hydrophobic and large-molecular-weight perfume substances that could not be clathrated in cyclodextrin. With the goal.

In addition, the present invention applies a cyclic dextrin having a wider and variously sized internal space, releases a perfume substance enclosed in the internal space of the cyclic dextrin, and encloses the source of the offensive odor. It is another object to provide a composition and method of expression that delivers removal and odor.

Another object of the present invention is to provide a method for preparing a composition for removing undesirable molecules to which a highly branched cyclic dextrin is applied.

In order to achieve the above objects, the present invention provides a highly branched cyclic dextrin (HBCD) or a derivative thereof, a perfume enclosed in at least one internal space of the highly branched cyclic dextrin, and A composition for removing unwanted molecules is provided, comprising a solvent.

According to a preferred embodiment of the present invention, the highly branched cyclic dextrin has 16 to 100 D-glucoses linked by alpha-1,6-glucosidic bonds. can be in the form

Also, according to another preferred embodiment of the present invention, the highly branched cyclic dextrin may have a dextrose equivalent value of 5 or less.

According to still another preferred embodiment of the present invention, the highly branched cyclic dextrin is an oligosaccharide having α-D-glucose as a monomer and has the chemical formula (C ₆ H ₁₀ O ₅ )xH ₂ It can be a compound represented by O (x is an integer from 200 to 5,000).

Also, according to still another preferred embodiment of the present invention, the highly branched cyclic dextrin may have an average molecular weight of 30,000 to 1,000,000 g/mol.

Also, according to still another preferred embodiment of the present invention, the highly branched cyclic dextrin may comprise 0.01-20% by weight based on the total weight of the composition.

Also, according to still another preferred embodiment of the present invention, the solvent may include water.

Also, according to still another preferred embodiment of the present invention, the composition may further include a surfactant.

Also, according to still another preferred embodiment of the present invention, the composition may further include a water-soluble polymer.

Also, according to still another preferred embodiment of the present invention, the composition may further include a plant extract.

The composition for removing undesired molecules according to the present invention can remove undesired molecules that could not be clathrated by cyclodextrins, more specifically, by applying cyclic dextrins having wider and variously sized internal spaces. Not only is it easy to remove various off-flavour sources, but it is also capable of encapsulating a wider variety of perfume substances that cannot be clathrated with cyclodextrins and that are hydrophobic and have large molecular weights. Such compositions replace the perfume material in the highly branched cyclic dextrin with the off-flavour source, providing superior masking ability and highly favored odor, as well as removal of foreign substances such as undesirable molecules such as off-flavor sources. becomes possible.

In addition, the composition for removing undesirable molecules according to the present invention further includes a plant extract, which has a synergistic effect in removing offensive odors.

The following drawings attached to this specification illustrate preferred embodiments of the present invention, and serve to further understand the technical idea of the present invention together with the detailed description of the invention. It should not be construed as being limited only to the matters described in the drawings.
1 is a schematic diagram schematically showing the formation process of a highly branched cyclic dextrin according to the present invention; FIG.

Preferred embodiments of the present invention will now be described in detail with reference to the accompanying drawings. Prior to this, the terms and words used in the specification and claims should not be construed as being limited to their ordinary or dictionary meaning, and the inventors themselves have It should be interpreted with the meaning and concept according to the technical idea of the present invention according to the principle that the concept of the term can be properly defined. Therefore, the embodiments described in this specification and the configuration shown in the drawings are merely the most desirable embodiments of the present invention, and do not represent all the technical ideas of the present invention. It should be understood that there may be various equivalents and modifications that could be substituted for them at the time of filing.

The present invention is characterized by comprising highly branched cyclic dextrin (HBCD) or a derivative thereof, a perfume and a solvent enclosed in at least one internal space of the highly branched cyclic dextrin. It relates to compositions for removing unwanted molecules.

The present invention recognizes that the cyclodextrin used for removing offensive odors has a predetermined internal space and shape, so the source of offensive odors or fragrances to be enclosed is limited, and in order to improve this point, We devised a dextrin with a highly branched cyclic structure that has a wider and variously sized internal space, unlike cyclodextrin, which has a single structure. Such a dextrin with a highly branched cyclic structure not only has a remarkably improved ability to remove offensive odors compared to conventional cyclodextrin, but also encloses a perfume substance with a large molecular weight and hydrophobicity, which cyclodextrin cannot enclose. After confirming that it is possible, the inventors have completed the present invention in anticipation of having a more improved ability to remove offensive odors.

Consequently, the inventors of the present invention have found that when a specific plant extract is included together with a highly branched cyclic dextrin, the off-flavor removal effect is synergistic compared to when the highly branched cyclic dextrin or the plant extract is included alone. The present invention was completed by discovering the surprising fact that the

In the context of the present invention, undesired molecules mean organic fragrance molecules, which are sources of off-flavours with undesirable odors. Such odor sources can be present on textile surfaces such as carpets, household items such as kitchen countertops, dishes, floors, trash cans, ceilings, walls, air filters, and surfaces such as skin and hair. It is possible and according to the present invention to remove such undesired molecules, ie off-flavour sources. Such odor sources include substances such as (E)-5-methyl-2-hexenoic acid, 5-methyl-4-hexenoic acid, 6-heptenoic acid, isovaleric acid, 4-methylhexenoic acid or ethyloctanoic acid. is known as an offensive odor component that can occur in textiles (Flavor and Fragrance Journal, 2012, vol. 27, 89-94), and various studies on offensive odor components derived from the human body are also progressing (Anti-Aging Medicine , 2010, 7(6):60-65). For this reason, the offensive odor source in the present invention means a normal offensive odor component that can be generated in daily life, such as originating from the human body or from textiles, but is not limited to such examples.

The composition can exist as an emulsion/dispersoid or as a clear, single-sided solution.

For the removal of off-flavors from textiles or the human body, the compositions of the present invention are preferably clear, single-sided solutions, and are transparent or translucent, and preferably have a water-clear character.

Also, when the compositions of the present invention are used as detergents, softeners, shampoos, surface cleaners, emulsions/dispersoids are desirable, generally having a size of about 0.05 μm or greater, preferably about 0.1 μm or greater, and more preferably about 0.1 μm or greater. Desirably, it can have aggregates of micelles or vesicles of about 0.2 μm or more. Such compositions can exist as transparent, translucent, or opaque, depending on the type and concentration of materials in the composition.

The composition of the present invention must be a composition capable of effectively delivering highly branched cyclic dextrin or a derivative thereof, but is not limited to the dosage forms described above.

The components of the composition for removing unwanted molecules are described in greater detail below.

1) Highly branched cyclic dextrin (HBCD)

Cyclodextrins and their derivatives have commonly been used in compositions for removing unwanted substances. Cyclodextrins contain 6-8 glucoses, which have a donut-like ring structure. The specific bonding and structure between glucose in such cyclodextrin causes the cyclodextrin to have a rigid conical structure with a specific volume of space. Each interior space array is formed by an oxygen atom forming a glycoside bridge with a hydrogen atom. Therefore, the inner surface has a very high hydrophobicity, and the specific shape and physicochemical properties of the interior are organic molecules or parts of organic molecules that conform to the shape of the interior space of cyclodextrin or its derivatives. It was possible to remove offensive odor substances by absorbing In addition, it has a mechanism in which a fragrance with a pleasant fragrance is positioned within such a specific internal shape, and when there is an offensive odor, it substitutes for the fragrance and is included in the cyclodextrin.

The present invention attempts to compensate for the limitation of cyclodextrins by applying cyclic dextrins having wider and variously sized internal spaces instead of a single spatial structure like cyclodextrins.

The cyclic dextrin applicable to the present invention is a highly branched cyclic dextrin, and the highly branched cyclic dextrin is, like amylopectin, a highly branched linear chain formed by α-1,6 bonds. It refers to a chemical structure in which the linkage of a glucose polymer polysaccharide chain is broken, and the broken linkage has a cyclic chain using a branching enzyme. An example is shown in FIG. It is formed by a method as schematically shown.

More specifically, the highly branched cyclic dextrin used in the present invention can be represented by (C ₆ H ₁₀ O ₅ )xH ₂ O (x is an integer from 200 to 5,000), an oligosaccharide, which is an odorless white powder with α-D-glucose as a monomer, and has an average molecular weight of about 30,000 to 1,000,000 per mole (g/mol); preferably about 100,000 to 900,000, more preferably about 200,000 to 800,000, even more preferably about 300,000 to 700,000, most preferably about 400,000 to 600,000 . When the average molecular weight is less than 30,000 g/mol, the internal space is narrow, so the inclusion ability of large-sized malodorous components or scents of various sizes is poor. , the formulation stability and molecular stability of the composition are inhibited. The degree of polymerization is 2500 glucose units. Also, the dextrose equivalent (DE) value, ie, the reducing power of D-glucose, is desirably 5 or less. Also, preferably, 16 to 100 D-glucoses are linked by side chain α-1,6-glucosidic bonds to the linear chain by α-1,4 bonds. It is a form that has been Due to this binding structure, the highly branched cyclic dextrin has a cyclic alpha-glucan moiety.

As described above, when the highly branched cyclic dextrin according to the present invention has the conditions such as the average molecular weight, the equivalent weight and the number of linear D-glucoses, it is easily dissolved in water to be more suitable for the purpose of the present invention, The inclusion ability of incense becomes more desirable.

Further, the dextrin derivative having a highly branched cyclic structure is a dextrin derivative of the present invention that maintains the basic structure so that all the functions of the present invention can be obtained from the structural characteristics of the dextrin having a highly branched cyclic structure according to the present invention. means a structure in which the atoms or atomic groups in the portion that does not affect the function of are substituted.

Thus, the use of highly branched, highly branched cyclic dextrins in compositions according to the present invention improves the ability of the compositions to bind undesirable molecules on treated surfaces, Undesirable molecules on the surface can be more effectively reduced or removed even at lower concentrations compared to dextrin derivatives.

More specifically, as a structural feature of the highly branched cyclic dextrin according to the present invention, at least one of the internal spaces of the highly branched cyclic dextrin absorbs various organic molecules or a part of the organic molecule. Since it is made possible (to form a polymer), it is possible to take in the internal space not only undesirable organic molecules, including offensive odor molecules, but also foreign matter on the surface of the object. Therefore, the dextrin having a highly branched cyclic structure according to the present invention having interiors of various sizes can not only remove offensive odors generated by broadly defined organic aromatic molecules having various active groups, but also have excellent residual fragrance. ClogP of good odor masking is 3 or higher and boiling point is 250° C. or higher.

In order for the highly branched cyclic dextrin to function within the present composition, at least about 0.01-20%, preferably about 0.05-10%, more preferably about 0% by weight of the total composition. .1-5% by weight. When the above content is included, it is effective not only in removing offensive odors but also in delivering fragrance ingredients. In that case, a problem arises in the formulation stability of the composition.

2) Perfume The perfume according to the present invention is included in at least one cyclic structure of the dextrin having a highly branched cyclic structure and forms a stable composition. The stable composition of the present invention provides a perceptual quality of pleasant fragrance, which, when applied to the surface of fabrics, human bodies, etc., removes foreign substances, ie, offensive odors, and imparts a refreshing feeling. The perfume in the present invention can provide at least a long-lasting fragrance.

The perfume that can be included in the dextrin having a highly branched cyclic structure according to the present invention is characterized in that various perfumes can be included regardless of whether they are hydrophilic or hydrophobic. Since the structural dextrin can include not only perfumes that can be included in cyclodextrin, but also perfumes that could not be included with cyclodextrin, it can be seen that various perfumes can be included. That is, the perfume included in the dextrin having a high-molecular cyclic structure according to the present invention is not limited to a specific perfume, and includes various perfumes.

On the other hand, the fragrance rate of incense is the ratio of alcohol to the perfume stock solution, and the fragrance rate of the incense according to the present invention is about 0% to about 3%, preferably about 0.003% to about 2%, of the entire composition. , and more preferably from about 0.005% to about 1%.

The present invention eliminates off-flavours and adds fragrances to make the fragrance on the surface more persistent. When a strong and strong scent is required, a perfume with a high fragrance addition rate or a perfume with an excellent lingering scent can be used. Any type of perfume can be applied in the composition of the present invention and perfume ingredients can be both hydrophobic or hydrophilic.

For longer lasting fragrance, the perfume should have at least partial hydrophobicity and a relatively high boiling point. That is, incense is mainly composed of incense raw materials belonging to the following two groups. (a) a hydrophobic component with a ClogP of 3.0 or higher, preferably a ClogP of 3.5 or higher; and (b) a perfume ingredient having a molecular weight of 205 or higher, preferably 210 or higher, more preferably 220 or higher.

The properties of the perfume ingredients include various isomers and have a great influence on substances existing in the surroundings, so it is difficult to clearly distinguish them from numerical values such as ClogP and molecular weight, which are physical properties. Therefore, the above numerical values should be interpreted flexibly in the interpretation of the above numerical ranges as approximate values for indicating the properties of fragrances.

For such hydrophobic perfumes, the weight ratio of highly branched cyclic dextrin to perfume is from about 2:1 to about 200:1, preferably from about 4:1 to about 100:1, more preferably from about 6:1 to about 200:1. :1 to about 50:1, more preferably about 8:1 to about 30:1 (highly branched cyclic dextrin:perfume).

Hydrophobic perfumes have the property of strongly binding to cyclic dextrins. The hydrophobicity of a perfume ingredient is related to the octanol/water partitioning coefficient P of that ingredient, which is the equilibrium concentration ratio of the perfume in octanol and water. A perfume with a higher partitioning factor P is more hydrophobic, and conversely a perfume with a lower partitioning factor P is more hydrophilic. Due to the generally high splitting factor of perfumes, it can be conveniently expressed in the form of logP using base 10 logs. Thus, other perfumes in the present invention have a logP value of about 3 or greater, preferably about 3.1 or greater, and most preferably about 3.2 or greater.

Also, the hydrophobic perfume composition each comprises at least about 5% to 80%, preferably about 10% to 60%, more preferably about 15% to 40% by weight of the total perfume composition.

More specifically, the highly branched cyclic dextrin according to the present invention includes Galxolide, Iso-E super, Helvetolide, and Cashmeran, which are perfumes that cyclodextrin could not include. , Cervolid, Aurantiol, and the like. Such fragrances have excellent ability to mask offensive odors, have a high preference for fragrances, and have a large molecular weight, so that they can more easily improve the lasting power of fragrances as hydrophobic fragrances.

Table 1 below shows the feasibility of binding several lingering fragrances to cyclodextrins and highly branched cyclic dextrins according to the invention. Since the highly branched cyclic dextrin according to the present invention has more diverse and wider internal spaces than cyclodextrins, it can enclose perfumes with large molecular weights that cannot be contained in cyclodextrins with ClogP of 3.0 or more. can. Therefore, more odors can be applied using the highly branched cyclic dextrins according to the present invention, thus broadening the odor spectrum of the composition and increasing the persistence of the lingering scent.

Perfume formulations for the present invention generally comprise at least 4 hydrophobic lingering perfumes, preferably 5, more preferably 6 and even more preferably 7 hydrophobic lingering perfumes. Also, the most widely used naturally derived fragrances consist of multiple constituents.

Hydrophilic perfumes are also characterized by good release from highly branched cyclic dextrins in water-soluble compositions, and such hydrophilic perfumes predominantly have a ClogP of about 3.5, preferably about 3.0 or less. It consists of ingredients that have

If the perfume ingredients are hydrophilic, they are dissolved in water-soluble compositions and are not highly bound to cyclic dextrins. In order to maintain the function of the cyclic dextrin to reduce and remove foreign substances such as offensive odors, the weight ratio of the hydrophilic perfume to the highly branched cyclic dextrin is about 90% by weight or less, preferably 50% by weight or less, more preferably 50% by weight or less. should be present in an amount of 30% by weight or less, more preferably 10% by weight or less. Desirably, such a ratio of cyclic dextrin to hydrophilic perfume is about 8:1 or greater, more preferably about 10:1 or greater, even more preferably about 20:1 or greater, and most preferably about 70:1 ( Cyclic dextrin: hydrophilic perfume) or more.

In addition, in the present composition, the perfume may be present in an amount of 0.1 to 10.0% by weight, preferably 0.5 to 5.0% by weight, based on the weight of the entire composition in order to play its role, When the above content is included, it is possible to maximize the improvement of sensory qualities of fragrance.

3) Solvent
In the present invention, the solvent means a transporter, preferably water, and distilled water, water from which ions have been removed, or tap water can also be used. Water not only acts as a transporter for highly branched cyclic dextrins, but can also facilitate the binding of foreign substances such as off-odor molecules on the treated surface to highly branched cyclic dextrins. In addition, it is known that if a surface contaminated with an offensive odor generated by organic amines, acids, mercaptans, etc., which are polar and have a small molecular weight, is treated with an aqueous solution, the strength is reduced. It is believed that water used as the solvent in the present invention solubilizes polar, low-molecular-weight offensive odor molecules and reduces the vapor pressure, thereby reducing the offensive odor intensity.

The concentration of solvent, ie, water, used within the compositions of the present invention may vary depending on the use of the composition (eg, dosage form, etc.). Compositions for passive or automatically propelled sprays desirably contain from about 30% to about 99.9%, more desirably from about 50% to about 99% by weight of water, based on the weight of the total composition. .9 wt%, more desirably from about 60 wt% to about 95 wt%, which is very high.

In addition, in the composition for removing offensive odors from fabrics, alcohol can be used as a solvent, preferably a lower alcohol having 1 to 4 carbon atoms, such as methanol or ethanol. It can be used at a concentration of less than about 20%, preferably less than about 10%, and more preferably less than about 5% by weight of alcohol based on the weight of the total composition.

Dilution of the aqueous solution can increase the coverage of the highly branched cyclic dextrin on the fabric and maximize the chances that the highly branched cyclic dextrin molecule and the off-flavour molecule can bind.

4) Surfactant The surfactant of the present invention may be further included in the composition of the present invention in order to appropriately reduce or remove foreign matter on the surface of the object or to allow the fragrance component to emit fragrance for a long time. can be done. For proper removal of off-flavours, the surfactant includes a stable surfactant that can easily bind to the highly branched cyclic dextrin of the present invention and off-flavours that are less likely to be included in the highly branched cyclic dextrin of the present invention. The properties of forming a polymer with a hydrophilic material and generating low surface tension to spread more easily and evenly on hydrophobic surfaces such as textiles are important.

Surfactants used in the present invention are of the type commonly used in detergents, softeners, shampoos, surface cleansers, cosmetics, body products, mouthwashes, body soaps, shaving products, moisturizers and the like. can contain things.

Highly branched cyclic dextrin-stable surfactant compositions can be used to dry faster and remove off-flavours from treated objects faster, depending on the type and characteristics of the surfactant applied. can. Some components of the composition, such as fragrances that do not dissociate well by clathrate with highly branched cyclic dextrin, promote highly branched cyclic dextrin and surfactant, micelle or vesicle formation, and have an appropriate strength at the time of use. Perfume retention contributes to enhancing the advantage of long-lasting fragrance from the treated surface during use.

The binding force between the surfactant and the highly branched cyclic dextrin according to the present invention can be understood by confirming the change in interfacial tension (dyne/cm) depending on whether or not the highly branched cyclic dextrin is added to the surfactant aqueous solution. The aqueous surfactant solution contains about 0.5%, about 0.1%, about 0.01%, about 0.005% concentration of surfactant, and the interfacial tension and If the increase in interfacial tension of an aqueous solution containing the same concentration of surfactant and further containing about 1% by weight of highly branched cyclic dextrin is about 10% or more, the binding between surfactant and cyclic dextrin is strong. exists.

Desirable surfactants in compositions according to the present invention are those whose interfacial tension changes are either weakly bound (interfacial tension increases less than about 5%) or not bound (interfacial tension is about 1 % rise).

Typical surfactant concentrations in compositions according to the present invention are from about 0.01% to about 2%, desirably from about 0.03% to about 0.6%, by weight of the total composition. % by weight, more preferably from about 0.05% to about 0.3% by weight. The concentration of surfactant in the surfactant concentrate composition is generally from about 0.1 wt% to about 20 wt%, preferably from about 0.2 wt% to about 15 wt%, more preferably about 0.3 wt%. % to about 10% by weight, but not limited thereto.

Examples of effective surfactants in the composition are as follows, but are not limited thereto. Examples of such include block polymer surfactants, siloxane surfactants, anionic surfactants, amphoteric surfactants, cationic surfactants, castor oil surfactants, sorbitan ester surfactants, polyoxyethylene surfactants. fatty alcohol surfactants, glycerol monovalent fatty acid ester surfactants, polyethylene glycol fatty acid ester surfactants, carbonized fluorosurfactants, and mixtures thereof.

The block polymer surfactant includes block polymers of ethylene oxide and propylene oxide, such as Pluronic (registered trademark) and Tetronic (registered trademark).

The siloxane surfactant is preferably a polyalkylene oxide polysiloxane as an anionic surfactant, and has a hydrophobic portion of dimethylpolysiloxane and a more hydrophilic polyalkylene chain. Examples of such surfactants include the Silwet® family. The number of ethyleneoxy (--C ₂ H ₄ O) units in the polyether chain (R ¹ ) must be sufficient so that the polyalkylene oxide polysiloxane is water soluble. If the propyleneoxy groups are present within a polyalkyleneoxy chain, they can be randomly positioned within the chain or present in blocks. Besides surface activity, polyalkylene oxide polysiloxane surfactants also have additional effects such as antistatic and softness of fabrics.

Examples of the anionic surfactants include alkyl diphenyl oxide disulfonates, alkyl ether sulfonates, and the like. In addition, anionic surfactants that can be used in detergents and shampoos include ammonium lauryl sulfate, ammonium laureth sulfate, triethylamine lauryl sulfate, triethylamine laureth sulfate, monovalent ethanolamine lauryl sulfate, monovalent ethanolamine laureth. Sulfates, diethanolamine lauryl sulfate, diethanolamine laureth sulfate, lauric monovalent glyceride sodium sulfate, sodium lauryl sulfate, potassium lauryl sulfate, potassium laureth sulfate, ammonium cocoyl sulfate, ammonium laureth sulfate, sodium Didium cocoyl sulfate, sodium lauroyl sulfate, potassium cocoyl sulfate, potassium lauroyl sulfate, triethanolamine lauryl sulfate, triethanolamine laureth sulfate, monovalent ethanolamine cocoyl sulfate, monovalent ethanolamine lauryl There are sulfates, sodium N-lauoyl-N methyl taurate, sodium tridecylbenzene sulfate, and sodium dodecylbenzene sulfate. Detergent anionic surfactants suitable for the present composition are selected from ammonium laureth-3-sulfate, laureth-3-sulfate chloride, ammonium lauryl sulfate, lauryl chloride sulfate, and mixtures thereof. Such anionic surfactants are desirable because when cationic antibacterial agents or preservatives are used, they reduce binding with cationic surfactants and reduce the effect of surfactants and antibacterial agents. do not have.

A wide variety of amphoteric surfactants can be used in the compositions of the present invention. In particular, aliphatic secondary and tertiary amine derivatives are desirable, and these aliphatic radicals have linear or branched structures, one of which is carboxy, sulfonate, sulfate, phosphate, etc. It has an ionizable water-soluble functional group. Examples of amphoteric or cationic surfactants are betaines, sultaines and hydroxysultaines. Betaines include cocodimethylcarboxymethylbetaine, lauryldimethylcarboxyethylbetaine (Lonzaine 16SP, manufactured by Lonzq), laurylbis-(2-hydroxyethyl)carboxymethylbetaine, stearylbis-(2-hydroxypropyl)carboxymethylbetaine, oleyldimethyl gamma-carboxypropyl betaine, laurylbis-(2-hydroxypropyl)α-carboxyethylbetaine, cocodimethylsulfopropylbetaine, stearyldimethylsulfopropylbetaine, stearylbetaine, lauryldimethylsulfoethylbetaine, laurylbis-(2-hydroxyethyl)sulfo Propyl betaine, and amidobetaine and amidosulfobetaine (RCONH(CH ₂ ) ₃ radical is attached to nitrogen atom of betaine), oleyl betaine (aliphatic Velvetex OLB-50, Henkel), cocamidopropyl betaine (Velvetex BK-35 and BA-35, manufactured by Henkel). Sultaine and hydroxysultaine include cocamidopropyl hydroxysultaine (Mirataine CBS, manufactured by Rhone Poulenc).

Other surfactants include surfactants derived from amino acids, and the surfactants contain the basic chemical structure of amino acids, that is, the structure of natural amino acids. Surfactants are generally derived from glycine and sarcosine, glutamic acid, arginine, alanine, N-methylglycine such as phenylalanine.

The cationic surfactants generally contain a quaternary nitrogen, and the fatty acids may contain or bind other functional groups in addition to carbon and hydrogen, such as amino groups. Fatty acids with long chains of about 12 carbon atoms or more can be saturated or unsaturated. In particular, two long alkyl chains having about 12 to about 22 carbons, preferably about 16 to about 22 carbons, and two long alkyl chains having about 1 to about 3 carbons, preferably about 1 to about 2 carbons. Cationic substances with short alkyl chains or with one long alkyl chain and three short alkyl chains are preferred. Also, at least one substituent is hydroxyalkyl, preferably hydroxyethyl or hydroxypropyl, or polyoxyalkylene, and the degree of ethoxylation or propoxylation in the entire molecule is about 5 to about 20, or Polyoxypropylene is preferred. Salts of primary, secondary and tertiary amines are also desirable as cationic surfactants. The alkyl groups of such amines desirably have from about 12 to about 22 carbons and can be substituted or unsubstituted.

Said castor oil surfactant is partially or wholly hydrotreated polyoxyethylene castor oil ether or polyoxyethylene compressed castor oil or mixtures thereof with cyclic dextrin-incompatible surfactants. It is advantageous for forming molecular polymers such as micelles and vesicles.

The sorbitan ester surfactants having a long fatty acid chain containing 14-18 or 16-18 carbon atoms are cyclic dextrin-compatible surfactants, wherein the cyclic Forms molecular polymers with dextrin-incompatible substances. Common examples of sorbitan polyesters with long fatty acid chains are sorbitan tripalmitate, sorbitan trioleate, sorbitan tallow fatty acid triester. Other sorbitan ester surfactants include sorbitan fatty acid esters partially having monovalent and trivalent esters. Still other sorbitan ester surfactants include polyethoxylated sorbitan fatty acid esters.

The polyethoxylated fatty acid ester surfactants include polyethoxylated fatty alcohol surfactants. Branched (polyethoxylated) fatty alcohols act as cyclic dextrin-compatible surfactants in the present compositions. Glycerol monovalent fatty acid esters, which are glycerol monovalent fatty acid ester surfactants, include glycerol monovalent stearate, oleate, palmitate, and laurate. Polyethylene glycol fatty acid ester surfactants act as cyclic dextrin-compatible surfactants. Fluorocarbon surfactants have at least a fluorine with the hydrophobic portion of the amphoteric moiety being part of a carbon-based linear or cyclic functional group attached to the carbon, generally hydrophilic with the hydrogens attached together. form the sexual part. Some common fluorocarbon surfactants include ionic surfactants such as fluorinated alkyl polyoxyalkylenes and fluorinated alkyl esters.

5) Water-soluble polymer In the present invention, a water-soluble polymer may be further included in the composition of the present invention. Water-soluble polymers, such as water-soluble cationic polymers and water-soluble anionic polymers, are further desirably included in the compositions of the present invention as they have additional off-flavour-removing effects. Representative examples of water-soluble cationic polymers include polyamines. Water-soluble cationic polymers contain amino groups, amide groups, and mixtures thereof, and are used to remove specific acid odors.

Water-soluble anionic polymers such as polyacrylic acid and its water-soluble salts are also used to eliminate certain amine odors. Polyacrylic acids and their alkali metal salts have an average molecular weight of less than about 20,000, desirably less than 5,000. Polymers containing sulfate groups, phosphate groups, phosphonic acids, their water-soluble salts and mixtures thereof, mixtures of carboxylic acids and carboxyl groups can also be used. Water-soluble polymers having both cationic and anionic functional groups can also be used. When water-soluble polymers are used, they are generally used in an amount of from about 0.001% to about 3%, preferably from about 0.01% to about 1%, more preferably about 0.05%, by weight of the total composition. % to about 0.5% by weight is used.

6) Plant extract The composition for removing undesirable molecules according to the present invention synergistically enhances the deodorizing effect by adding a highly branched cyclic dextrin and a plant extract with excellent deodorizing effect. The plant extract adsorbs and decomposes bad odors, has excellent deodorizing power and long-lasting deodorizing power, is safe for the human body, and permanently decomposes the adsorbed bad odors and does not emit them again.

The plant extracts that can be used in the present invention may include one or more plant extracts selected from the group consisting of green tea, persimmon leaves, cinnamon peel, and star anise. Preferably, the plant extract may be a mixture containing all extracts of green tea, persimmon leaf, chinpi, and star anise. A mixture containing star anise extract at a weight ratio of about 1:1:1:1. In such cases, the deodorizing effect of the composition for removing unwanted molecules is the best for the purposes of the present invention.

Plant extracts that can be used in the present invention may be plant solvent extracts extracted from plants using commonly used water or organic solvents such as ethanol and hexane. Preferably, the plant solvent extract is extracted from the plant by hot water extraction. More preferably, the plant extract may be a reaction product of a plant solvent extract containing polyphenolic plant essential oil and minerals. Said mineral may be a silicate mineral such as talc, kaolin, zeolite or mica, preferably zeolite.

The reaction product of the plant solvent extract and the mineral contains many ionized substances, unlike the mere plant extract. The plant extract prepared by the above method contains ionized substances such as O ₂ , H, OH, etc., and induces repetitive interaction effects of such elements, and amines, mercaptans, or sulfurs. It exhibits excellent deodorizing power by reacting with malodorous molecules such as In addition, the plant extract is harmless to the human body, and permanently decomposes the odor that has been absorbed into the deodorant, thereby preventing the odor from remaining in the deodorant and providing excellent deodorizing power.

The plant extract in the composition for removing unwanted molecules according to the present invention is 0.01-10% by weight, preferably 0.05-5% by weight, more preferably 0.1-10% by weight, based on the total weight of the composition. 3% by weight. If the amount of the plant extract is less than 0.01% by weight, the deodorizing effect is not sufficiently exhibited. and the dosage form stability is deteriorated. Therefore, the weight ratio of the highly branched cyclic dextrin and the plant extract in the composition for removing undesirable molecules is preferably 0.1:1 to 1:0.1, more preferably 0.2. :1 to 1:0.2, more preferably 0.3:1 to 1:0.3 (highly branched cyclic dextrin:plant extract).

7) Other ingredients In the composition of the present invention, other diluents, excipients, antibacterial agents, skin protectants, antistatic agents, moisturizing agents or plant extracts (except green tea, persimmon leaves, citrus peel and star anise) It can further include objects and the like.

The compositions for removing undesired molecules of the present invention are also used in applications such as laundry detergents, softeners, surface cleaners, kitchen detergents, deodorants, shampoos, hair conditioners, body products, and armpit deodorants. can be, but are not limited to.

In addition, the present invention contains highly branched cyclic dextrin (HBCD) or a derivative thereof in an amount of 0.01 to 10% by weight based on the total weight of the composition, and a plant containing green tea, persimmon leaves, citrus peel and star anise. A composition for removing unwanted molecules is provided comprising 0.01 to 10% by weight of the extract. Desirably, said highly branched cyclic dextrin has an average molecular weight of 30,000 to 1,000,000 g/mol. For purposes of the present invention, a composition for removing undesirable molecules containing the above weight ratios of ingredients has significantly better deodorizing effects.

In addition, the composition for removing undesirable molecules according to the present invention comprises a step of (s1) reacting a plant extract containing 0.01 to 10% by weight of polyphenolic plant essential oil with respect to the total weight of the composition with minerals. and (s2) adding 0.01 to 10% by weight of highly branched cyclic dextrin (HBCD) or its derivative to the reactant in step (s1) and mixing. can be done. Desirably, said highly branched cyclic dextrin has an average molecular weight of 30,000 to 1,000,000 g/mol. Preferably, the plant may include one or more plants selected from the group consisting of green tea, persimmon leaves, chinpi, and star anise. More preferably, green tea, persimmon leaves, chinpi, and star anise. can include all

In addition, highly branched cyclic dextrin (HBCD) or a derivative thereof according to the present invention, perfume and solvent enclosed in at least one internal space of the highly branched cyclic dextrin, and optionally, surfactant, water A method for removing undesirable molecules, preferably a method for deodorizing malodors such as with ammonia or methyl mercaptan, comprising the step of treating a composition for the removal of undesirable molecules comprising a toxic polymer, a plant extract or a mixture thereof.

Hereinafter, the present invention will be described with specific examples. However, embodiments according to the present invention can be modified in many other forms, and should not be construed as limiting the scope of the present invention to the embodiments set forth below. Rather, the embodiments of the present invention are provided so that this disclosure will be more thorough and complete for those of ordinary skill in the art.

<Example>
Since the composition according to the invention consists of substances such as highly branched cyclic dextrin, perfume and solvent, it is important that the functionality of the highly branched cyclic dextrin is present in the composition during the production process of the composition. In order to retain a functional hyperbranched cyclic dextrin in the composition, the initial hyperbranched cyclic dextrin and surfactant must be mixed. As a result, after the formation of molecular polymers such as micelles and vesicles, highly branched cyclic dextrin-surfactant molecular polymers are impregnated with substances such as fragrances to form highly branched cyclic dextrin. It can be effectively isolated from the interior space and retain the composition that functions within the composition.

In the present invention, compositions were prepared, applied and evaluated in spray form for removing odors from fabrics, particularly dry fabrics. However, the efficacy of the present invention is not limited to said dosage forms. It is desirable to use a composition to which a low concentration of highly branched cyclic dextrin is applied in order not to leave stains on the fabric with a general usage amount, such as a spray type formulation used for the purpose of removing offensive odors from fabric. The solution applied to the surface of the object under conditions of use must not be visible after drying.

Under normal use conditions, the weight of total highly branched cyclic dextrins in the composition is typically about 0.01-20%, preferably about 0.05-10%, more preferably about 0.1-5%. % by weight. Most desirably, it contains at least about 0.1% to 5% by weight in order for the highly branched cyclic dextrin to function within the composition. Compositions with high concentrations can leave a macroscopic stain on the fabric as it dries, which can be a problem especially in light colored synthetic fabrics.

Compositions of fragrances included in one embodiment of the present invention are shown in Table 2 below, and contents of compositions containing the fragrances are shown in Table 3 below.

1. Evaluation of Offensive Odor Intensity The offensive odor removing effects of the compositions of Comparative Examples and Examples were evaluated as follows.

1) The woven fabric for evaluation is a cotton towel cut into a size of 30 cm x 30 cm, which is washed in a washing machine using an unscented detergent and dried in a dryer.
2) Apply about 80 μL of the off-flavour formulation to a dry cotton towel in an area of 5 cm×5 cm on each fabric, place in a plastic bag, seal and leave overnight at room temperature.
3) A trained evaluator evaluates the initial off-flavor intensity of the off-flavor-applied fabric and scores according to the following off-flavor rating scale.
4) The formulation to be evaluated is then applied to the fabric in equal amounts and allowed to dry for 30 seconds.
5) Once the fabric is dry, the evaluator scores the offensive odor intensity of the fabric to which the offensive odor is applied according to the offensive odor rating scale below.
6) Record the initial score and the subsequent score, and calculate the offensive odor reduction value from the score difference.

There were eight evaluators in total, and in order to clearly recognize the standard offensive odor, the pre-educated evaluation was conducted one by one in a separate evaluation booth equipped with forced ventilation equipment, and the accuracy of the evaluation was confirmed. More than three assessments at a time were restricted for safety reasons.

Table 4 below shows off-flavor evaluation criteria.

In addition, in order to evaluate the lingering scent with cyclic dextrin, the scent strength was evaluated after 10 minutes and 30 minutes, and the lingering scent increasing effect of cyclic dextrin was evaluated.

Table 5 below shows the lingering scent evaluation criteria.

2. Evaluation results About 80 μL of the off-flavor formulation was applied to a cotton towel cut to 30 cm × 30 cm on an area of 5 cm × 5 cm on each fabric, sealed in a plastic bag, and left overnight at room temperature. The panel evaluated the intensity of the offensive odor, giving a score of 4.2.

Table 6 shows the difference between the evaluation results after drying for 30 seconds after application to Comparative Example 1 and Examples 1 to 7 and the evaluation results obtained by evaluating only the offensive odor source.

It was found that Examples 1 to 7 using cyclic dextrin exhibited an excellent offensive odor removing effect as compared with Comparative Example 1 using cyclodextrin as the offensive odor removing base. Comparing Comparative Example 1 and Example 1, only the odor-removing base is different. . It can be seen that cyclic dextrin is superior to cyclodextrin in removing offensive odor when the offensive odor removing base has the same content.

In addition, in Examples 2 and 3, when Copolymer 958, which is a cyclic dextrin-compatible polymer, was applied, it was found that the odor removal effect of cyclic dextrin was increased. Comparing Example 4 and Example 5, it was found that Example 4, which has a higher content of perfume, is superior when the content of perfume is changed to 0.10% and 0.06%, respectively. Further, when comparing Example 2 and Example 4 in which the application of Velvetex BK-35, which is an amphoteric surfactant, is different, the results of Example 4 in which Velvetex BK-35 is applied are superior. Do you get it. By comparing Example 6 and Example 7, it was found that the addition of a cyclic dextrin-compatible polymer and an amphoteric surfactant, which can provide a synergistic effect in removing offensive odors of cyclic dextrin, increased the offensive odor removing effect.

In addition, Table 7 shows the evaluation results of the lingering scent intensity after 10 minutes and 30 minutes. Comparing Comparative Example 1 with Examples 1 to 7, it was found that the difference in the lingering scent attribute was greater after 30 minutes than after 10 minutes. It can be determined from this that cyclic dextrin clathrates more perfume ingredients with a ClogP of 3.0 or higher and a boiling point of 250° C. or higher than cyclodextrin and releases them over time.

In addition, the higher the cyclic dextrin content, the smaller the difference between the residual fragrance after 10 minutes and the residual fragrance after 30 minutes, thus reconfirming this fact. From the comparison between Example 6 and Example 7, the lingering effect of cyclic dextrin is further enhanced when adding polymers, amphoteric surfactants, which can increase the mutual adhesion between perfume and fiber. Confirmed to do.

<Production of Examples 8 to 16 and Comparative Example 2>
In the preparation of the deodorant compositions of Examples 8-16 and Comparative Example 2, the highly branched cyclic dextrin (HBCD) was an oligosaccharide, an odorless white powder made from α-D-glucose as a monomer. A mixture having an average molecular weight in the range of about 30,000 to 1,000,000 per mole (g/mol) was used in the range of 0 to 0.8% by weight.

The plant extract is made by mixing 50 g each of dried green tea, persimmon leaves, chinpi and star anise, and extracting them in 5 L of purified water at 110°C for 60 minutes with hot water. It is a plant extract obtained by reacting minerals such as and used in the range of 0 to 1% by weight.

In addition to the highly branched cyclic dextrin and plant extract, other surfactants, fragrances, additives, etc. were added to purified water and mixed, and the composition ratios shown in Table 8 below were used in Examples 8 to 16 and Comparative Examples. Two deodorant compositions were prepared.

3. Deodorizing Power Evaluation of the Deodorant Compositions of Examples 8-16 and Comparative Example 2 The deodorizing power test was trained for ammonia and methyl mercaptan, for detector tube, detector pump measurement methods and food malodors according to ASTM D1988. A sensory evaluation method, which is an evaluation of the odor intensity by the evaluator, was used.

Methyl mercaptan is diluted to 0.1% reagent grade in benzene, ammonia is diluted to 0.05% in water and used as a source of odor. was used after diluting to a concentration of The gas suction pump is a GV-100S Air Sampling Pump, Gastec co. (Japan), and the gas detector tube is Gastec Detector tube No. 71 (Methyl mercaptan), Gastec Detector tube no. 3La (Ammonia) was used.

Deodorization rate for ammonia and methyl mercaptan is evaluated by putting a certain amount of purified water or undiluted sample solution into a 250 mL container, then adding malodorous solution and sealing it. The malodor concentration was reported.

Calculation of deodorization rate is (Foul odor detection concentration of detector tube when using purified water, ppm) - (Foul odor detection concentration of detector tube when using sample, ppm) / (Foul odor detection concentration of detector tube when using purified water , ppm) was multiplied by 100 (%), and the percentage was calculated and used as the deodorizing rate.

The deodorization rate of kimchi jjigae was evaluated by a trained evaluator by evaluating the initial odor strength of the fabric to which the malodor was applied using an evaluation scale. A malodor reduction value was calculated from the difference in evaluation scores that evaluated malodor intensity. The food odor evaluation scale of kimchi jjigae is scored on a scale of 0 to 5, and the higher the score, the better the deodorizing power.

As a result of the evaluation, the deodorant compositions of Examples 8 to 16, in which the highly branched cyclic dextrin was individually prescribed or in which the plant extract was mixed, compared with Comparative Example 2 in which the plant extract was prescribed individually. It was found that the product has excellent deodorizing power against ammonia and methyl mercaptan, and against the foul food odor of kimchi jjigae.

Claims (8)

introducing and mixing a highly branched cyclic dextrin (HBCD) or a derivative thereof and a hydrophobic perfume having a ClogP of 3 or more into a solvent;
A method for producing a highly branched cyclic dextrin containing a fragrance in the inner space. The highly branched cyclic dextrin is in a form in which 16 to 100 D-glucoses are linked by α-1,6-glucosidic bonds, and the perfume is wrapped in the internal space of claim 1. A method for producing a tangential highly branched cyclic dextrin. [Claim 2] The method for producing a highly branched cyclic dextrin containing a perfume in the internal space according to claim 1, wherein the highly branched cyclic dextrin has a dextrose equivalent value of 5 or less. The highly branched cyclic dextrin is an oligosaccharide having α-D-glucose as a monomer and is represented by the chemical formula (C ₆ H ₁₀ O ₅ )xH ₂ O (where x is an integer of 200 to 5,000). 2. The method for producing a highly branched cyclic dextrin having a perfume enclosed in the internal space according to claim 1, wherein the compound is a compound that is The hyperbranched cyclic dextrin containing perfume in the inner space according to claim 1, wherein the hyperbranched cyclic dextrin has an average molecular weight of 30,000 to 1,000,000 g/mol. Production method. 2. The method for producing a highly branched cyclic dextrin having a perfume enclosed in the internal space according to claim 1, wherein the solvent contains water. [Claim 2] The method of claim 1, wherein the step further comprises adding and mixing a surfactant into the solvent, to prepare a highly branched cyclic dextrin having a perfume enclosed in the inner space. [Claim 2] The method of claim 1, wherein the step further comprises adding and mixing a water-soluble polymer into the solvent.

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