JP2021534188A5 - - Google Patents
Info
- Publication number
- JP2021534188A5 JP2021534188A5 JP2021507982A JP2021507982A JP2021534188A5 JP 2021534188 A5 JP2021534188 A5 JP 2021534188A5 JP 2021507982 A JP2021507982 A JP 2021507982A JP 2021507982 A JP2021507982 A JP 2021507982A JP 2021534188 A5 JP2021534188 A5 JP 2021534188A5
- Authority
- JP
- Japan
- Prior art keywords
- approximately
- pharmaceutical composition
- composition according
- cancer
- integer
- Prior art date
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862719189P | 2018-08-17 | 2018-08-17 | |
| US62/719,189 | 2018-08-17 | ||
| US201862733380P | 2018-09-19 | 2018-09-19 | |
| US62/733,380 | 2018-09-19 | ||
| US201962808376P | 2019-02-21 | 2019-02-21 | |
| US62/808,376 | 2019-02-21 | ||
| US201962854701P | 2019-05-30 | 2019-05-30 | |
| US62/854,701 | 2019-05-30 | ||
| PCT/US2019/046852 WO2020037225A1 (en) | 2018-08-17 | 2019-08-16 | Napi2b-targeted polymer antibody-drug conjugates and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021534188A JP2021534188A (ja) | 2021-12-09 |
| JPWO2020037225A5 JPWO2020037225A5 (https=) | 2022-08-15 |
| JP2021534188A5 true JP2021534188A5 (https=) | 2022-08-15 |
Family
ID=67841175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021507982A Ceased JP2021534188A (ja) | 2018-08-17 | 2019-08-16 | ＮａＰｉ２ｂに標的指向されたポリマー抗体−薬物コンジュゲートおよびその使用方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11407825B2 (https=) |
| EP (1) | EP3836972A1 (https=) |
| JP (1) | JP2021534188A (https=) |
| KR (1) | KR20210049122A (https=) |
| CN (1) | CN113194999A (https=) |
| AU (1) | AU2019320818A1 (https=) |
| BR (1) | BR112021002747A2 (https=) |
| CA (1) | CA3109790A1 (https=) |
| IL (1) | IL280867A (https=) |
| MX (1) | MX2021001924A (https=) |
| TW (1) | TW202035452A (https=) |
| WO (1) | WO2020037225A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| KR102799807B1 (ko) | 2015-12-30 | 2025-04-24 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| MX2020009152A (es) | 2018-03-02 | 2020-11-09 | Kodiak Sciences Inc | Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos. |
| KR20210049122A (ko) * | 2018-08-17 | 2021-05-04 | 메르사나 테라퓨틱스, 인코포레이티드 | NaPi2b 표적화 폴리머 항체-약물 접합체 및 이것의 사용 방법 |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| US20220370631A1 (en) * | 2021-05-03 | 2022-11-24 | Mersana Therapeutics, Inc. | Combination therapy of carboplatin and napi2b-targeted polymer antibody-drug conjugate for the treatment of ovarian cancer |
| WO2023039512A1 (en) * | 2021-09-09 | 2023-03-16 | Mersana Therapeutics, Inc. | Napi2b-targeted polymer antibody-drug conjugate for the treatment of ovarian cancer |
| US20240190958A1 (en) * | 2022-10-18 | 2024-06-13 | Tubulis Gmbh | Novel antibody drug conjugates with novel napi2b antibodies, therapeutic methods and uses thereof |
| TW202530268A (zh) * | 2023-10-19 | 2025-08-01 | 加拿大商酵活英屬哥倫比亞有限公司 | 抗ｎａｐｉ２ｂ抗體－藥物結合物及使用方法 |
| KR102764613B1 (ko) | 2024-03-28 | 2025-02-12 | 한양대학교 에리카산학협력단 | NaPi2b 특이적 CAR-T를 포함하는 난소암 치료용 약학 조성물 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| DE3900534A1 (de) | 1989-01-10 | 1990-07-12 | Boehringer Mannheim Gmbh | Diagnostischer nachweis unter verwendung von chimaeren antikoerpern |
| CH694588A5 (de) | 1999-02-09 | 2005-04-15 | Hoffmann La Roche | Menschliche intestinale Npt2B. |
| MXPA05000511A (es) | 2001-07-12 | 2005-09-30 | Jefferson Foote | Anticuepros super humanizados. |
| WO2003060086A2 (en) | 2002-01-15 | 2003-07-24 | Board Of Regents, The University Of Texas System | Napi type iib polypeptides and methods for making and using same |
| US7498298B2 (en) | 2003-11-06 | 2009-03-03 | Seattle Genetics, Inc. | Monomethylvaline compounds capable of conjugation to ligands |
| US8383799B2 (en) | 2006-01-20 | 2013-02-26 | Cell Signaling Technology, Inc. | Translocation and mutant ROS kinase in human non-small cell lung carcinoma |
| CN101568349B (zh) | 2006-10-25 | 2012-09-19 | 威斯康星大学校友研究基金会 | 减少磷酸盐吸收的方法 |
| WO2009097128A1 (en) | 2008-01-29 | 2009-08-06 | Ludwig Institute For Cancer Research Ltd. | Membrane transporter napi2b (slc34a2) epitope for antibody therapy, antibodies directed thereto, and target for cancer therapy |
| US8742076B2 (en) | 2008-02-01 | 2014-06-03 | Genentech, Inc. | Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods |
| CN102159248B (zh) | 2008-07-15 | 2013-09-11 | 健泰科生物技术公司 | 蒽环类衍生物缀合物、它们的制备方法以及它们作为抗肿瘤化合物的用途 |
| JP5370826B2 (ja) | 2009-04-20 | 2013-12-18 | 株式会社パソロジー研究所 | 癌の組織型を判別するカクテル抗体、判別キット及び判別方法 |
| BR112012012750A2 (pt) | 2009-11-30 | 2020-08-11 | Genentech Inc | anticorpo isolado, célula, ácido nucleíco isolado e método |
| EP2590655B1 (en) | 2010-07-07 | 2015-06-24 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| JP5823514B2 (ja) | 2010-07-07 | 2015-11-25 | アーデリクス，インコーポレーテッド | リン酸輸送を阻害する化合物及び方法 |
| WO2012006477A1 (en) | 2010-07-07 | 2012-01-12 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| JP5827327B2 (ja) | 2010-07-07 | 2015-12-02 | アーデリクス，インコーポレーテッド | リン酸輸送を阻害する化合物及び方法 |
| WO2012171020A1 (en) | 2011-06-10 | 2012-12-13 | Mersana Therapeutics, Inc. | Protein-polymer-drug conjugates |
| EA032231B1 (ru) * | 2013-10-11 | 2019-04-30 | Мерсана Терапьютикс, Инк. | Конъюгаты белок-полимер-лекарственное средство |
| CA2927022C (en) | 2013-10-11 | 2018-08-21 | Asana Biosciences, Llc | Protein-polymer-drug conjugates |
| WO2015195925A1 (en) * | 2014-06-18 | 2015-12-23 | Mersana Therapeutics, Inc. | Protein-polymer-drug conjugates and methods of using same |
| MX2017007169A (es) * | 2014-12-03 | 2018-05-02 | Genentech Inc | Compuestos de amina cuaternaria y conjugados de anticuerpofármaco de los mismos. |
| JP7023841B2 (ja) | 2015-10-23 | 2022-02-22 | エフ．ホフマン－ラ ロシュ アーゲー | マーカー分子に基づいて個体を化学療法により処置すべきであると同定する方法および関連する使用 |
| WO2017160753A1 (en) | 2016-03-14 | 2017-09-21 | The Penn State Research Foundation | Novel selenazolidine and thiazolidine compounds for treating cancer and other diseases |
| CN109310885B (zh) | 2016-03-15 | 2022-05-31 | 梅尔莎纳医疗公司 | NaPi2b靶向抗体-药物缀合物及其使用方法 |
| JP7320458B2 (ja) | 2017-06-22 | 2023-08-03 | メルサナ セラピューティクス インコーポレイテッド | 薬物担持ポリマースキャフォールドおよびタンパク質－ポリマー－薬物コンジュゲートを製造する方法 |
| EP3685166A2 (en) | 2017-09-20 | 2020-07-29 | Mersana Therapeutics, Inc. | Compositions and methods for predicting response to napi2b-targeted therapy |
| KR20210049122A (ko) * | 2018-08-17 | 2021-05-04 | 메르사나 테라퓨틱스, 인코포레이티드 | NaPi2b 표적화 폴리머 항체-약물 접합체 및 이것의 사용 방법 |
-
2019
- 2019-08-16 KR KR1020217008012A patent/KR20210049122A/ko not_active Abandoned
- 2019-08-16 AU AU2019320818A patent/AU2019320818A1/en not_active Abandoned
- 2019-08-16 JP JP2021507982A patent/JP2021534188A/ja not_active Ceased
- 2019-08-16 BR BR112021002747-5A patent/BR112021002747A2/pt not_active IP Right Cessation
- 2019-08-16 US US16/542,642 patent/US11407825B2/en active Active
- 2019-08-16 CN CN201980068682.0A patent/CN113194999A/zh active Pending
- 2019-08-16 WO PCT/US2019/046852 patent/WO2020037225A1/en not_active Ceased
- 2019-08-16 TW TW108129249A patent/TW202035452A/zh unknown
- 2019-08-16 CA CA3109790A patent/CA3109790A1/en active Pending
- 2019-08-16 EP EP19762538.7A patent/EP3836972A1/en not_active Withdrawn
- 2019-08-16 MX MX2021001924A patent/MX2021001924A/es unknown
-
2021
- 2021-02-15 IL IL280867A patent/IL280867A/en unknown
-
2022
- 2022-06-28 US US17/851,618 patent/US20220332815A1/en not_active Abandoned
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