JP2021533166A5 - - Google Patents

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Publication number
JP2021533166A5
JP2021533166A5 JP2021506492A JP2021506492A JP2021533166A5 JP 2021533166 A5 JP2021533166 A5 JP 2021533166A5 JP 2021506492 A JP2021506492 A JP 2021506492A JP 2021506492 A JP2021506492 A JP 2021506492A JP 2021533166 A5 JP2021533166 A5 JP 2021533166A5
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JP
Japan
Prior art keywords
component
target ligand
car
payload drug
drug
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Application number
JP2021506492A
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English (en)
Japanese (ja)
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JP7623935B2 (ja
JPWO2020033129A5 (https=
JP2021533166A (ja
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Priority claimed from PCT/US2019/042726 external-priority patent/WO2020033129A1/en
Publication of JP2021533166A publication Critical patent/JP2021533166A/ja
Publication of JP2021533166A5 publication Critical patent/JP2021533166A5/ja
Publication of JPWO2020033129A5 publication Critical patent/JPWO2020033129A5/ja
Application granted granted Critical
Publication of JP7623935B2 publication Critical patent/JP7623935B2/ja
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JP2021506492A 2018-08-07 2019-07-21 Car t細胞の若返り Active JP7623935B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862715666P 2018-08-07 2018-08-07
US62/715,666 2018-08-07
PCT/US2019/042726 WO2020033129A1 (en) 2018-08-07 2019-07-21 Rejuvenation of car t cell

Publications (4)

Publication Number Publication Date
JP2021533166A JP2021533166A (ja) 2021-12-02
JP2021533166A5 true JP2021533166A5 (https=) 2022-07-28
JPWO2020033129A5 JPWO2020033129A5 (https=) 2022-07-28
JP7623935B2 JP7623935B2 (ja) 2025-01-29

Family

ID=69415080

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021506492A Active JP7623935B2 (ja) 2018-08-07 2019-07-21 Car t細胞の若返り

Country Status (9)

Country Link
US (2) US20210308267A1 (https=)
EP (1) EP3833400A4 (https=)
JP (1) JP7623935B2 (https=)
KR (1) KR20210042125A (https=)
CN (2) CN112543651B (https=)
AU (1) AU2019317278B2 (https=)
CA (1) CA3108710A1 (https=)
SG (1) SG11202100616VA (https=)
WO (1) WO2020033129A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2934532B1 (en) 2012-12-20 2019-10-23 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
JP7282521B2 (ja) 2016-04-08 2023-05-29 パーデュー・リサーチ・ファウンデイション Car t細胞療法のための方法および組成物
JP7178355B2 (ja) 2017-02-28 2022-11-25 エンドサイト・インコーポレイテッド Car t細胞療法のための組成物および方法
JP7549303B2 (ja) 2018-01-22 2024-09-11 エンドサイト・インコーポレイテッド Car t細胞の使用方法
CN112105382A (zh) 2018-02-23 2020-12-18 恩多塞特公司 用于car t细胞疗法的顺序方法
CN112262214A (zh) 2018-04-12 2021-01-22 优莫佳生物制药股份有限公司 病毒载体及包装细胞系
AU2021217003A1 (en) 2020-02-04 2022-09-15 Seattle Children's Hospital (dba Seattle Children's Research Institute) Anti-dinitrophenol chimeric antigen receptors
US20240058458A1 (en) * 2020-03-06 2024-02-22 Purdue Research Foundation Methods, compounds, and compositions for modifying car-t cell activity
CN116096861A (zh) * 2020-04-03 2023-05-09 赛立维公司 过继性细胞转移的增强
US20240293456A1 (en) * 2020-11-30 2024-09-05 Purdue Research Foundation Combinations of small molecule drug conjugate and car-expressing cytotoxic lymphocytes and methods of treating cancer using the same
US20240390505A1 (en) * 2021-08-30 2024-11-28 Purdue Research Foundation Conjugates, compositions, and methods for rejuvenation of car t-cells
JP2025506652A (ja) * 2022-02-18 2025-03-13 エフ. ホフマン-ラ ロシュ アーゲー 試料中の目的の分析物を検出するための方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8933197B2 (en) * 2007-08-15 2015-01-13 Amunix Operating Inc. Compositions comprising modified biologically active polypeptides
KR102339240B1 (ko) * 2013-10-15 2021-12-15 더 스크립스 리서치 인스티튜트 펩타이드 키메라 항원 수용체 t 세포 스위치 및 이의 용도
EP3057991B8 (en) * 2013-10-15 2019-09-04 The Scripps Research Institute Chimeric antigen receptor t cell switches and uses thereof
ES2918501T3 (es) * 2013-12-19 2022-07-18 Novartis Ag Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos
WO2015092024A2 (en) * 2013-12-20 2015-06-25 Cellectis Method of engineering multi-input signal sensitive t cell for immunotherapy
EP3593812A3 (en) * 2014-03-15 2020-05-27 Novartis AG Treatment of cancer using chimeric antigen receptor
KR20160145802A (ko) * 2014-04-23 2016-12-20 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 요법에 사용하기 위한 키메라 항원 수용체 (car) 및 이의 제조 방법
US20180243340A1 (en) * 2015-08-24 2018-08-30 University Of Houston System Combination therapy combining car + t cells with appropriately timed immunodulatory antibodies
CN109415687A (zh) * 2016-04-07 2019-03-01 蓝鸟生物公司 嵌合抗原受体t细胞组合物
JP7282521B2 (ja) * 2016-04-08 2023-05-29 パーデュー・リサーチ・ファウンデイション Car t細胞療法のための方法および組成物
WO2017205661A1 (en) * 2016-05-25 2017-11-30 Purdue Research Foundation Method of treating cancer by targeting myeloid-derived suppressor cells
CN116474108A (zh) * 2016-12-14 2023-07-25 普渡研究基金会 成纤维细胞活化蛋白(fap)-靶向成像和治疗
CN110662839A (zh) * 2017-02-17 2020-01-07 珀杜研究基金会 用于细胞疗法的基于靶向性配体-有效负载的药物递送

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