JP2021531448A5 - - Google Patents
Info
- Publication number
- JP2021531448A5 JP2021531448A5 JP2020564556A JP2020564556A JP2021531448A5 JP 2021531448 A5 JP2021531448 A5 JP 2021531448A5 JP 2020564556 A JP2020564556 A JP 2020564556A JP 2020564556 A JP2020564556 A JP 2020564556A JP 2021531448 A5 JP2021531448 A5 JP 2021531448A5
- Authority
- JP
- Japan
- Prior art keywords
- drug
- drug target
- antibody
- target
- ada
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024023599A JP2024045646A (ja) | 2018-07-10 | 2024-02-20 | 抗薬物抗体（ａｄａ）免疫アッセイにおける薬物標的干渉を軽減するための方法 |
| JP2025179025A JP2026012856A (ja) | 2018-07-10 | 2025-10-23 | 抗薬物抗体（ａｄａ）免疫アッセイにおける薬物標的干渉を軽減するための方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862696016P | 2018-07-10 | 2018-07-10 | |
| US62/696,016 | 2018-07-10 | ||
| PCT/US2019/040950 WO2020014194A1 (en) | 2018-07-10 | 2019-07-09 | Methods for mitigating drug target interference in an anti-drug antibody (ada) immunoassay |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024023599A Division JP2024045646A (ja) | 2018-07-10 | 2024-02-20 | 抗薬物抗体（ａｄａ）免疫アッセイにおける薬物標的干渉を軽減するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021531448A JP2021531448A (ja) | 2021-11-18 |
| JP2021531448A5 true JP2021531448A5 (enExample) | 2022-07-11 |
| JP7493459B2 JP7493459B2 (ja) | 2024-05-31 |
Family
ID=67544324
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020564556A Active JP7493459B2 (ja) | 2018-07-10 | 2019-07-09 | 抗薬物抗体（ａｄａ）免疫アッセイにおける薬物標的干渉を軽減するための方法 |
| JP2024023599A Pending JP2024045646A (ja) | 2018-07-10 | 2024-02-20 | 抗薬物抗体（ａｄａ）免疫アッセイにおける薬物標的干渉を軽減するための方法 |
| JP2025179025A Pending JP2026012856A (ja) | 2018-07-10 | 2025-10-23 | 抗薬物抗体（ａｄａ）免疫アッセイにおける薬物標的干渉を軽減するための方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024023599A Pending JP2024045646A (ja) | 2018-07-10 | 2024-02-20 | 抗薬物抗体（ａｄａ）免疫アッセイにおける薬物標的干渉を軽減するための方法 |
| JP2025179025A Pending JP2026012856A (ja) | 2018-07-10 | 2025-10-23 | 抗薬物抗体（ａｄａ）免疫アッセイにおける薬物標的干渉を軽減するための方法 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US12055551B2 (enExample) |
| EP (1) | EP3821255B1 (enExample) |
| JP (3) | JP7493459B2 (enExample) |
| KR (1) | KR102754704B1 (enExample) |
| CN (1) | CN112384808B (enExample) |
| AU (1) | AU2019301614B2 (enExample) |
| BR (1) | BR112020022912A2 (enExample) |
| EA (1) | EA202190237A1 (enExample) |
| ES (1) | ES2993989T3 (enExample) |
| IL (1) | IL277888B2 (enExample) |
| MA (1) | MA53130A (enExample) |
| MX (1) | MX2021000331A (enExample) |
| MY (1) | MY207418A (enExample) |
| SG (1) | SG11202011283TA (enExample) |
| WO (1) | WO2020014194A1 (enExample) |
| ZA (1) | ZA202006409B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2022011336A (es) * | 2020-03-17 | 2022-10-07 | Regeneron Pharma | Atenuacion de la interferencia de dianas en ensayo de anticuerpos antifarmacos. |
| CN114264814B (zh) * | 2021-12-30 | 2025-03-14 | 苏州和锐生物科技有限公司 | 一种pd-1生物制剂的抗体检测试剂盒及制备方法 |
| CN114324894A (zh) * | 2021-12-31 | 2022-04-12 | 军科正源（北京）药物研究有限责任公司 | 一种检测贝伐珠单抗抗药性抗体的新型分析方法 |
| CN114047343B (zh) * | 2022-01-13 | 2022-05-31 | 美迪西普亚医药科技(上海)有限公司 | 双耐受型抗IgE单抗药物的免疫原性分析试剂盒及其使用方法和应用 |
| WO2023204378A1 (ko) * | 2022-04-19 | 2023-10-26 | 의료법인 성광의료재단 | 혈액 내 항-약물항체 농도 측정을 통한 생물학적 약물에 대한 치료 반응성 예측 방법 |
| CN119790065A (zh) * | 2022-08-24 | 2025-04-08 | 美国安进公司 | 抗药物抗体测定 |
| CN115586337A (zh) * | 2022-09-14 | 2023-01-10 | 杭州赛基生物科技有限公司 | 检测肿瘤伴随诊断相关因子的试剂盒及其制备方法 |
| CN120239821A (zh) * | 2022-09-23 | 2025-07-01 | 默沙东有限责任公司 | 中和抗体测定方法 |
| CN115575468B (zh) * | 2022-09-30 | 2025-08-26 | 华润生物医药有限公司 | 一种检测抗重组人GLP-1-Fc融合蛋白抗体的方法 |
| CN115856322A (zh) * | 2022-12-23 | 2023-03-28 | 同昕生物技术（北京）有限公司 | 用于抗奥马株单抗药物抗体检测的试剂及其应用 |
| CN117805382B (zh) * | 2024-02-28 | 2024-05-03 | 军科正源（北京）药物研究有限责任公司 | 检测抗利妥昔单抗中和抗体的方法 |
| WO2025224166A1 (en) * | 2024-04-23 | 2025-10-30 | F. Hoffmann-La Roche Ag | Anti-drug antibody assays |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3856469A (en) * | 1973-01-02 | 1974-12-24 | Syva Corp | Interferant removal from amphetamine immunoassay |
| JPS55145690A (en) | 1979-05-04 | 1980-11-13 | Toyama Chem Co Ltd | Novel penicillin and cephalosporin, and its salt |
| JPS6454356A (en) * | 1987-08-26 | 1989-03-01 | Meidensha Electric Mfg Co Ltd | Method for suppressing non-specific adsorption of antibody to solid phase antigen |
| JPH02138872A (ja) | 1988-11-18 | 1990-05-28 | Asahi Chem Ind Co Ltd | 癌関連物質のための免疫測定方法 |
| WO2005031353A1 (ja) | 2003-09-26 | 2005-04-07 | Matsushita Electric Industrial Co., Ltd. | 免疫反応測定方法、ならびにそれに用いる試薬、キット、及び光学セル |
| EP2142925A1 (en) | 2007-05-07 | 2010-01-13 | Wyeth a Corporation of the State of Delaware | Elimination of interference in immunoassays caused by anti-carbohydrate antibodies |
| WO2009022001A1 (en) * | 2007-08-16 | 2009-02-19 | Novartis Ag | Improvement of drug tolerance in immunogenicity testing |
| CA3141978A1 (en) * | 2011-06-23 | 2012-12-27 | Ablynx Nv | Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains |
| JP6563910B2 (ja) | 2013-07-04 | 2019-08-21 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 血清サンプル中の抗薬物抗体を検出するための干渉抑制イムノアッセイ |
| EP4137816B1 (en) | 2014-02-11 | 2025-03-19 | Genzyme Corporation | Assays for detecting the presence or amount of an anti-drug antibody |
| WO2017096262A1 (en) * | 2015-12-04 | 2017-06-08 | Jomoco, Corp. | Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates |
| US20190145985A1 (en) | 2017-11-10 | 2019-05-16 | BioAgilytix Labs, LLC | Method for eliminating target interference |
| JP7161534B2 (ja) | 2017-11-29 | 2022-10-26 | エフ．ホフマン－ラ ロシュ アーゲー | 標的による干渉が抑制された抗薬物抗体アッセイ |
| MX2022011336A (es) * | 2020-03-17 | 2022-10-07 | Regeneron Pharma | Atenuacion de la interferencia de dianas en ensayo de anticuerpos antifarmacos. |
-
2019
- 2019-07-09 BR BR112020022912-1A patent/BR112020022912A2/pt unknown
- 2019-07-09 JP JP2020564556A patent/JP7493459B2/ja active Active
- 2019-07-09 US US16/506,379 patent/US12055551B2/en active Active
- 2019-07-09 WO PCT/US2019/040950 patent/WO2020014194A1/en not_active Ceased
- 2019-07-09 AU AU2019301614A patent/AU2019301614B2/en active Active
- 2019-07-09 KR KR1020207033049A patent/KR102754704B1/ko active Active
- 2019-07-09 EP EP19749872.8A patent/EP3821255B1/en active Active
- 2019-07-09 MX MX2021000331A patent/MX2021000331A/es unknown
- 2019-07-09 MA MA053130A patent/MA53130A/fr unknown
- 2019-07-09 MY MYPI2020005155A patent/MY207418A/en unknown
- 2019-07-09 CN CN201980046236.XA patent/CN112384808B/zh active Active
- 2019-07-09 IL IL277888A patent/IL277888B2/en unknown
- 2019-07-09 EA EA202190237A patent/EA202190237A1/ru unknown
- 2019-07-09 SG SG11202011283TA patent/SG11202011283TA/en unknown
- 2019-07-09 ES ES19749872T patent/ES2993989T3/es active Active
-
2020
- 2020-10-15 ZA ZA2020/06409A patent/ZA202006409B/en unknown
-
2024
- 2024-02-20 JP JP2024023599A patent/JP2024045646A/ja active Pending
- 2024-07-03 US US18/763,265 patent/US20240353423A1/en active Pending
-
2025
- 2025-10-23 JP JP2025179025A patent/JP2026012856A/ja active Pending
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