JP2021530971A5 - - Google Patents

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Publication number
JP2021530971A5
JP2021530971A5 JP2020571816A JP2020571816A JP2021530971A5 JP 2021530971 A5 JP2021530971 A5 JP 2021530971A5 JP 2020571816 A JP2020571816 A JP 2020571816A JP 2020571816 A JP2020571816 A JP 2020571816A JP 2021530971 A5 JP2021530971 A5 JP 2021530971A5
Authority
JP
Japan
Prior art keywords
seq
acid sequence
her2
tac
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020571816A
Other languages
English (en)
Japanese (ja)
Other versions
JP7404279B2 (ja
JP2021530971A (ja
Filing date
Publication date
Priority claimed from US16/442,274 external-priority patent/US10640562B2/en
Application filed filed Critical
Priority claimed from PCT/US2019/042297 external-priority patent/WO2020018727A1/en
Publication of JP2021530971A publication Critical patent/JP2021530971A/ja
Publication of JP2021530971A5 publication Critical patent/JP2021530971A5/ja
Application granted granted Critical
Publication of JP7404279B2 publication Critical patent/JP7404279B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020571816A 2018-07-17 2019-07-17 様々な構築物最適化を備えたt細胞抗原カプラ Active JP7404279B2 (ja)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US201862699173P 2018-07-17 2018-07-17
US62/699,173 2018-07-17
US201862703037P 2018-07-25 2018-07-25
US62/703,037 2018-07-25
US201862773120P 2018-11-29 2018-11-29
US62/773,120 2018-11-29
US201962826853P 2019-03-29 2019-03-29
US62/826,853 2019-03-29
US201962828879P 2019-04-03 2019-04-03
US62/828,879 2019-04-03
US201962839235P 2019-04-26 2019-04-26
US62/839,235 2019-04-26
US16/442,274 US10640562B2 (en) 2018-07-17 2019-06-14 T cell-antigen coupler with various construct optimizations
US16/442,274 2019-06-14
US201962874426P 2019-07-15 2019-07-15
US62/874,426 2019-07-15
PCT/US2019/042297 WO2020018727A1 (en) 2018-07-17 2019-07-17 T cell-antigen coupler with various construct optimizations

Publications (3)

Publication Number Publication Date
JP2021530971A JP2021530971A (ja) 2021-11-18
JP2021530971A5 true JP2021530971A5 (OSRAM) 2022-07-14
JP7404279B2 JP7404279B2 (ja) 2023-12-25

Family

ID=69163917

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020571816A Active JP7404279B2 (ja) 2018-07-17 2019-07-17 様々な構築物最適化を備えたt細胞抗原カプラ

Country Status (12)

Country Link
EP (1) EP3823984A4 (OSRAM)
JP (1) JP7404279B2 (OSRAM)
KR (1) KR102834084B1 (OSRAM)
CN (1) CN112689642B (OSRAM)
AU (1) AU2019307905B2 (OSRAM)
BR (1) BR112021000735A2 (OSRAM)
CA (1) CA3104887A1 (OSRAM)
IL (1) IL280049A (OSRAM)
MX (1) MX2021000541A (OSRAM)
PH (1) PH12021550114A1 (OSRAM)
SG (1) SG11202100307WA (OSRAM)
WO (1) WO2020018727A1 (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106459990B (zh) 2014-02-07 2021-06-01 麦克马斯特大学 三功能t细胞抗原偶联物及其制备方法和用途
JP7227630B2 (ja) 2017-10-12 2023-02-22 マックマスター ユニバーシティー Y182t突然変異を有するt細胞-抗原カプラおよびその方法ならびに使用
US10640562B2 (en) 2018-07-17 2020-05-05 Mcmaster University T cell-antigen coupler with various construct optimizations
US11110123B2 (en) 2018-07-17 2021-09-07 Triumvira Immunologics Usa, Inc. T cell-antigen coupler with various construct optimizations
EP4326888A1 (en) 2021-04-21 2024-02-28 Conagen Inc. Biosynthetic production of gamma-or delta-lactones using cytochrome p450 hydroxylase enzymes or mutants thereof
EP4347660A4 (en) * 2021-06-01 2025-06-04 Triumvira Immunologics USA, Inc. CLAUDIN-18.2 T-CELL ANTIGEN COUPLER AND USES THEREOF
US11453723B1 (en) 2021-06-25 2022-09-27 Mcmaster University BCMA T cell-antigen couplers and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6441079B2 (ja) * 2011-12-19 2018-12-19 シンイミューン ゲーエムベーハー 二重特異性抗体分子
AU2013289971A1 (en) * 2012-07-13 2015-01-22 The Trustees Of The University Of Pennsylvania Enhancing activity of CAR T cells by co-introducing a bispecific antibody
CN106459990B (zh) * 2014-02-07 2021-06-01 麦克马斯特大学 三功能t细胞抗原偶联物及其制备方法和用途
MX2017012939A (es) * 2015-04-08 2018-05-22 Novartis Ag Terapias cd20, terapias cd22 y terapias de combinacion con una celula que expresa un receptor quimerico de antigeno (car) de cd19.
WO2016166139A1 (en) * 2015-04-14 2016-10-20 Eberhard Karls Universität Tübingen Bispecific fusion proteins for enhancing immune responses of lymphocytes against tumor cells
AU2017292936C1 (en) * 2016-07-08 2024-05-02 Exuma Biotech, Corp. Methods and compositions for transducing lymphocytes and regulating the activity thereof
CA3032838A1 (en) * 2016-08-04 2018-02-08 Memorial Sloan-Kettering Cancer Center Compositions and methods for immunotherapy
CN108250302A (zh) * 2016-12-29 2018-07-06 天津天锐生物科技有限公司 一种多功能蛋白质

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