JP2021530464A5 - - Google Patents

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Publication number
JP2021530464A5
JP2021530464A5 JP2020573421A JP2020573421A JP2021530464A5 JP 2021530464 A5 JP2021530464 A5 JP 2021530464A5 JP 2020573421 A JP2020573421 A JP 2020573421A JP 2020573421 A JP2020573421 A JP 2020573421A JP 2021530464 A5 JP2021530464 A5 JP 2021530464A5
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JP
Japan
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independently selected
alkyl
alkylene
optionally substituted
haloalkyl
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JP2020573421A
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English (en)
Japanese (ja)
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JP7565802B2 (ja
JP2021530464A (ja
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Priority claimed from PCT/US2019/039499 external-priority patent/WO2020006229A1/en
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Publication of JP2021530464A5 publication Critical patent/JP2021530464A5/ja
Priority to JP2024114813A priority Critical patent/JP7787250B2/ja
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Publication of JP7565802B2 publication Critical patent/JP7565802B2/ja
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JP2020573421A 2018-06-27 2019-06-27 炎症抑制用化合物 Active JP7565802B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024114813A JP7787250B2 (ja) 2018-06-27 2024-07-18 炎症抑制用化合物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862690788P 2018-06-27 2018-06-27
US62/690,788 2018-06-27
PCT/US2019/039499 WO2020006229A1 (en) 2018-06-27 2019-06-27 Compounds for inhibition of inflammation

Related Child Applications (1)

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JP2024114813A Division JP7787250B2 (ja) 2018-06-27 2024-07-18 炎症抑制用化合物

Publications (3)

Publication Number Publication Date
JP2021530464A JP2021530464A (ja) 2021-11-11
JP2021530464A5 true JP2021530464A5 (https=) 2022-07-04
JP7565802B2 JP7565802B2 (ja) 2024-10-11

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ID=68987150

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JP2020573421A Active JP7565802B2 (ja) 2018-06-27 2019-06-27 炎症抑制用化合物
JP2024114813A Active JP7787250B2 (ja) 2018-06-27 2024-07-18 炎症抑制用化合物

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JP2024114813A Active JP7787250B2 (ja) 2018-06-27 2024-07-18 炎症抑制用化合物

Country Status (8)

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US (1) US20210267996A1 (https=)
EP (1) EP3813805A4 (https=)
JP (2) JP7565802B2 (https=)
CN (1) CN112512515B (https=)
AU (2) AU2019293232B2 (https=)
BR (1) BR112020025018A2 (https=)
CA (1) CA3103432A1 (https=)
WO (1) WO2020006229A1 (https=)

Families Citing this family (13)

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Publication number Priority date Publication date Assignee Title
CN113189340A (zh) * 2020-01-14 2021-07-30 中国医学科学院基础医学研究所 细胞焦亡通路在细胞治疗中的用途
WO2021257880A1 (en) * 2020-06-18 2021-12-23 Spring Discovery, Inc. Use of aldh modulators or gasdermin d inhibitors for prevention and treatment of aging and aging-related disorders and for boosting an immune system
CN112011499B (zh) * 2020-09-10 2022-06-03 徐州医科大学 一种制备细胞外囊泡的方法及其应用
US11033516B1 (en) 2020-09-18 2021-06-15 Spring Discovery, Inc. Combination therapies with disulfiram
EP4112051A1 (en) * 2021-06-30 2023-01-04 Op2 Drugs Anethole trithione for the treatment of vasculitides
CN113462653B (zh) * 2021-07-05 2022-10-04 东北农业大学 抗猪Gasdermin D蛋白单克隆抗体、分泌该单克隆抗体杂交瘤细胞株及其应用
CN117642170A (zh) * 2021-07-15 2024-03-01 基因泰克公司 治疗性化合物及方法
CN113577288A (zh) * 2021-09-15 2021-11-02 皖南医学院第一附属医院（皖南医学院弋矶山医院） Mst4相关物质在制备治疗脑出血后神经炎症反应的药物中的应用
CN115819548B (zh) * 2021-11-16 2023-09-01 北京美德泰康生物科技有限公司 一种检测炎症相关疾病的标志物和方法
CN115947691B (zh) * 2022-03-01 2024-08-16 四川大学 哒嗪砜类衍生物及其用途
LU501764B1 (en) * 2022-03-31 2023-10-02 Leibniz Inst Fuer Naturstoff Forschung Und Infektionsbiologie E V Hans Knoell Inst Hki Gasdermin e expression in human t cells as a marker for proinflammatory t cell functions
CN115429794B (zh) * 2022-09-16 2023-11-17 温州医科大学附属口腔医院 3-甲基吲哚二甲基氨基二硫代酸酯在制备防治牙周炎药物的用途
CN119285558A (zh) * 2023-07-10 2025-01-10 四川大学 一类新型gsdmd抑制剂及其制备方法和用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870101A (en) * 1987-03-17 1989-09-26 Merrell Dow Pharmaceuticals Inc. Method of inhibiting interleukin-1 release
IL122892A0 (en) * 1998-01-11 1998-08-16 Yeda Res & Dev Pharmaceutical compositions comprising a thiocarbamate
US6548540B2 (en) * 1998-09-08 2003-04-15 Charlotte-Mecklenburg Hospital Authority Method of treating cancer using dithiocarbamate derivatives
NZ545724A (en) * 2003-03-18 2007-11-30 Protemix Corp Ltd Use of a copper chelator for preventing and/or treating cardiovascular disease and/or associated heart failure
EP2101567A4 (en) 2007-01-18 2010-04-21 Univ Utah Res Found COMPOSITIONS AND METHODS FOR DETECTING, TREATING OR PREVENTING REDUCED STRESS
WO2009062174A1 (en) 2007-11-08 2009-05-14 University Of Utah Research Foundation Use of angiogenesis antagonists in conditions of abnormal venous proliferation
US20100137787A1 (en) * 2008-12-02 2010-06-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Delivery devices for modulating inflammation
US20100135983A1 (en) * 2008-12-02 2010-06-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Anti-inflammatory compositions and methods
AU2012284223B2 (en) * 2011-07-18 2017-06-22 University Of Kentucky Research Foundation Protection of cells from Alu-RNA-induced degenereation and inhibitors for protecting cells
GB201804514D0 (en) * 2018-03-21 2018-05-02 Ucl Business Plc Treatment of pyroptosis

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