JP2021528455A5 - - Google Patents
Info
- Publication number
- JP2021528455A5 JP2021528455A5 JP2020572638A JP2020572638A JP2021528455A5 JP 2021528455 A5 JP2021528455 A5 JP 2021528455A5 JP 2020572638 A JP2020572638 A JP 2020572638A JP 2020572638 A JP2020572638 A JP 2020572638A JP 2021528455 A5 JP2021528455 A5 JP 2021528455A5
- Authority
- JP
- Japan
- Prior art keywords
- ethyl
- pyridine
- methoxyazetidine
- methoxy
- cyclopropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18180114.3 | 2018-06-27 | ||
| EP18180114 | 2018-06-27 | ||
| PCT/EP2019/066733 WO2020002270A1 (en) | 2018-06-27 | 2019-06-25 | Pyridine and pyrazine derivatives as preferential cannabinoid 2 agonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021528455A JP2021528455A (ja) | 2021-10-21 |
| JP2021528455A5 true JP2021528455A5 (enExample) | 2022-06-30 |
| JP7454512B2 JP7454512B2 (ja) | 2024-03-22 |
Family
ID=62814859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020572638A Active JP7454512B2 (ja) | 2018-06-27 | 2019-06-25 | 優先的カンナビノイド２アゴニストとしてのピリジン及びピラジン誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11655243B2 (enExample) |
| EP (1) | EP3814337B1 (enExample) |
| JP (1) | JP7454512B2 (enExample) |
| CN (1) | CN112074513B (enExample) |
| WO (1) | WO2020002270A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201904943A (zh) | 2017-06-20 | 2019-02-01 | 瑞士商赫孚孟拉羅股份公司 | 新穎吡啶衍生物 |
| CN112638430B (zh) * | 2018-06-27 | 2023-05-16 | 豪夫迈·罗氏有限公司 | 放射性标记的大麻素受体2配体 |
| CA3096777A1 (en) | 2018-06-27 | 2020-02-02 | F. Hoffmann-La Roche Ag | Novel pyridine and pyrazine compounds as inhibitors of cannabinoid receptor 2 |
| JP7478672B2 (ja) | 2018-06-27 | 2024-05-07 | エフ． ホフマン－ラ ロシュ アーゲー | カンナビノイド受容体２の阻害剤としての新規なアゼチジン置換ピリジン及びピラジン化合物 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200808769A (en) * | 2006-04-18 | 2008-02-16 | Astrazeneca Ab | Therapeutic compounds |
| CN101522644B (zh) * | 2006-10-04 | 2013-04-24 | 霍夫曼-拉罗奇有限公司 | 作为cb2受体调节剂的吡嗪-2-羧酰胺衍生物 |
| WO2009106561A1 (en) * | 2008-02-27 | 2009-09-03 | Biovitrum Ab (Publ) | Pyrazine compounds for treating gpr119 related disorders |
| US9321727B2 (en) | 2011-06-10 | 2016-04-26 | Hoffmann-La Roche Inc. | Pyridine derivatives as agonists of the CB2 receptor |
| WO2013037721A1 (en) * | 2011-09-12 | 2013-03-21 | F. Hoffmann-La Roche Ag | 5-cycloalkyl- or 5-heterocyclyl-nicotinamides |
| US9403808B2 (en) | 2011-10-28 | 2016-08-02 | Hoffmann-La Roche Inc. | Pyrazine derivatives |
| TW201326139A (zh) * | 2011-10-28 | 2013-07-01 | Hoffmann La Roche | 新穎吡□衍生物 |
| HRP20171459T1 (hr) | 2012-12-07 | 2017-11-03 | F. Hoffmann - La Roche Ag | Piridin-2-amidi korisni kao agonisti cb2 |
| HRP20180672T1 (hr) | 2012-12-07 | 2018-06-01 | F. Hoffmann - La Roche Ag | Novi derivati piridina |
| JP6426619B2 (ja) * | 2012-12-07 | 2018-11-21 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｃｂ２アゴニストとして有用なピリジン−２−アミド |
| SI2928882T1 (sl) | 2012-12-07 | 2017-05-31 | F. Hoffmann-La Roche Ag | Pirazinski derivati kot agonisti receptorja CB2 |
| PE20151559A1 (es) | 2013-03-26 | 2015-11-05 | Hoffmann La Roche | Nuevos derivados de piridina |
| MX2016012690A (es) * | 2014-04-04 | 2017-04-27 | Hoffmann La Roche | Piridin-2-carboxamidas 5,6-disustituidas como agonistas del receptor cannabinoide. |
| CN106132958A (zh) | 2014-04-04 | 2016-11-16 | 豪夫迈·罗氏有限公司 | 作为cb2激动剂的吡啶‑2‑酰胺类化合物 |
| SI3386951T1 (sl) | 2015-12-09 | 2020-07-31 | F. Hoffmann-La Roche Ag | Fenilni derivati kot agonisti kanabinoidnega receptorja 2 |
| TW201904943A (zh) | 2017-06-20 | 2019-02-01 | 瑞士商赫孚孟拉羅股份公司 | 新穎吡啶衍生物 |
| CN112638430B (zh) | 2018-06-27 | 2023-05-16 | 豪夫迈·罗氏有限公司 | 放射性标记的大麻素受体2配体 |
| JP7478672B2 (ja) | 2018-06-27 | 2024-05-07 | エフ． ホフマン－ラ ロシュ アーゲー | カンナビノイド受容体２の阻害剤としての新規なアゼチジン置換ピリジン及びピラジン化合物 |
| CA3096777A1 (en) | 2018-06-27 | 2020-02-02 | F. Hoffmann-La Roche Ag | Novel pyridine and pyrazine compounds as inhibitors of cannabinoid receptor 2 |
| TWI687701B (zh) | 2018-12-05 | 2020-03-11 | 宏碁股份有限公司 | 判斷電量狀態的方法及其電子裝置 |
-
2019
- 2019-06-25 EP EP19739206.1A patent/EP3814337B1/en active Active
- 2019-06-25 JP JP2020572638A patent/JP7454512B2/ja active Active
- 2019-06-25 CN CN201980029322.XA patent/CN112074513B/zh active Active
- 2019-06-25 WO PCT/EP2019/066733 patent/WO2020002270A1/en not_active Ceased
-
2020
- 2020-12-17 US US17/125,647 patent/US11655243B2/en active Active
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