JP2021527407A5 - - Google Patents

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Publication number
JP2021527407A5
JP2021527407A5 JP2020569166A JP2020569166A JP2021527407A5 JP 2021527407 A5 JP2021527407 A5 JP 2021527407A5 JP 2020569166 A JP2020569166 A JP 2020569166A JP 2020569166 A JP2020569166 A JP 2020569166A JP 2021527407 A5 JP2021527407 A5 JP 2021527407A5
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JP
Japan
Prior art keywords
disease
amyloidosis
amyloid
seq
protein
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JP2020569166A
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English (en)
Japanese (ja)
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JPWO2019241628A5 (https=
JP7549536B2 (ja
JP2021527407A (ja
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Priority claimed from PCT/US2019/037179 external-priority patent/WO2019241628A1/en
Publication of JP2021527407A publication Critical patent/JP2021527407A/ja
Publication of JPWO2019241628A5 publication Critical patent/JPWO2019241628A5/ja
Publication of JP2021527407A5 publication Critical patent/JP2021527407A5/ja
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JP2020569166A 2018-06-15 2019-06-14 全般的アミロイド相互作用モチーフ(gaim) Active JP7549536B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862685757P 2018-06-15 2018-06-15
US62/685,757 2018-06-15
US201862749499P 2018-10-23 2018-10-23
US62/749,499 2018-10-23
PCT/US2019/037179 WO2019241628A1 (en) 2018-06-15 2019-06-14 General amyloid interaction motif (gaim)

Publications (4)

Publication Number Publication Date
JP2021527407A JP2021527407A (ja) 2021-10-14
JPWO2019241628A5 JPWO2019241628A5 (https=) 2022-06-01
JP2021527407A5 true JP2021527407A5 (https=) 2022-06-01
JP7549536B2 JP7549536B2 (ja) 2024-09-11

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JP2020569166A Active JP7549536B2 (ja) 2018-06-15 2019-06-14 全般的アミロイド相互作用モチーフ(gaim)

Country Status (13)

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US (2) US11692017B2 (https=)
EP (2) EP3806884B1 (https=)
JP (1) JP7549536B2 (https=)
CN (1) CN112672755A (https=)
AU (1) AU2019287623B2 (https=)
BR (1) BR112020025111A2 (https=)
ES (1) ES2960493T3 (https=)
IL (1) IL279333B2 (https=)
MX (1) MX2020013525A (https=)
PL (1) PL3806884T3 (https=)
SG (1) SG11202012091WA (https=)
WO (1) WO2019241628A1 (https=)
ZA (1) ZA202100071B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3806884B1 (en) * 2018-06-15 2023-08-02 Amyl Therapeutics General amyloid interaction motif (gaim)
JP7505713B2 (ja) * 2019-02-22 2024-06-25 ロヨラ メリーマウント ユニバーシティ アミロイドペプチドバリアント
CN120641092A (zh) 2022-12-02 2025-09-12 阿尔泽恩股份有限公司 用于用曲米沙特治疗神经变性病症的方法
CN117343200B (zh) * 2023-12-04 2024-01-30 北京质肽生物医药科技有限公司 一种包含淀粉样核心多肽的融合蛋白、制备方法及其应用

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US3941763A (en) 1975-03-28 1976-03-02 American Home Products Corporation PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates
US4215051A (en) 1979-08-29 1980-07-29 Standard Oil Company (Indiana) Formation, purification and recovery of phthalic anhydride
JP4046354B2 (ja) 1996-03-18 2008-02-13 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 増大した半減期を有する免疫グロブリン様ドメイン
US8022270B2 (en) 2000-07-31 2011-09-20 Biolex Therapeutics, Inc. Expression of biologically active polypeptides in duckweed
PT1355919E (pt) 2000-12-12 2011-03-02 Medimmune Llc Moléculas com semivida longa, composições que as contêm e suas utilizações
US7217797B2 (en) 2002-10-15 2007-05-15 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
JP2007531707A (ja) 2003-10-15 2007-11-08 ピーディーエル バイオファーマ, インコーポレイテッド IGの重鎖定常領域の位置250、314および/または428の変異誘発によるFc融合タンパク質血清半減期の改変
CN114748605A (zh) * 2011-11-29 2022-07-15 普罗克拉拉生物科学股份有限公司 噬菌体基因3蛋白组合物及作为淀粉样蛋白结合剂的用途
CN104870008B (zh) 2012-10-02 2019-10-01 普罗克拉拉生物科学股份有限公司 噬菌体的p3融合蛋白作为淀粉样蛋白结合剂的用途
KR20160010618A (ko) 2013-05-28 2016-01-27 뉴로페이지 파마슈티컬즈, 인크. 감소된 면역원성을 갖는 개질된 박테리오파아지 g3p 아미노산 서열을 포함하는 폴리펩티드
PL3227313T3 (pl) 2014-12-03 2022-05-09 Proclara Biosciences, Inc. Polipeptydy zawierające zmodyfikowaną sekwencję aminokwasową bakteriofaga g3p pozbawioną sygnału glikozylacji
EP3806884B1 (en) * 2018-06-15 2023-08-02 Amyl Therapeutics General amyloid interaction motif (gaim)

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