JP2021527407A5 - - Google Patents

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Publication number
JP2021527407A5
JP2021527407A5 JP2020569166A JP2020569166A JP2021527407A5 JP 2021527407 A5 JP2021527407 A5 JP 2021527407A5 JP 2020569166 A JP2020569166 A JP 2020569166A JP 2020569166 A JP2020569166 A JP 2020569166A JP 2021527407 A5 JP2021527407 A5 JP 2021527407A5
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JP
Japan
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disease
amyloidosis
amyloid
seq
protein
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JP2020569166A
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English (en)
Japanese (ja)
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JP2021527407A (ja
JP7549536B2 (ja
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Priority claimed from PCT/US2019/037179 external-priority patent/WO2019241628A1/en
Publication of JP2021527407A publication Critical patent/JP2021527407A/ja
Publication of JP2021527407A5 publication Critical patent/JP2021527407A5/ja
Application granted granted Critical
Publication of JP7549536B2 publication Critical patent/JP7549536B2/ja
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JP2020569166A 2018-06-15 2019-06-14 全般的アミロイド相互作用モチーフ(gaim) Active JP7549536B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862685757P 2018-06-15 2018-06-15
US62/685,757 2018-06-15
US201862749499P 2018-10-23 2018-10-23
US62/749,499 2018-10-23
PCT/US2019/037179 WO2019241628A1 (en) 2018-06-15 2019-06-14 General amyloid interaction motif (gaim)

Publications (3)

Publication Number Publication Date
JP2021527407A JP2021527407A (ja) 2021-10-14
JP2021527407A5 true JP2021527407A5 (https=) 2022-06-01
JP7549536B2 JP7549536B2 (ja) 2024-09-11

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JP2020569166A Active JP7549536B2 (ja) 2018-06-15 2019-06-14 全般的アミロイド相互作用モチーフ(gaim)

Country Status (13)

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US (2) US11692017B2 (https=)
EP (2) EP3806884B1 (https=)
JP (1) JP7549536B2 (https=)
CN (1) CN112672755A (https=)
AU (1) AU2019287623B2 (https=)
BR (1) BR112020025111A2 (https=)
ES (1) ES2960493T3 (https=)
IL (1) IL279333B2 (https=)
MX (1) MX2020013525A (https=)
PL (1) PL3806884T3 (https=)
SG (1) SG11202012091WA (https=)
WO (1) WO2019241628A1 (https=)
ZA (1) ZA202100071B (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019241628A1 (en) * 2018-06-15 2019-12-19 Proclara Biosciences, Inc. General amyloid interaction motif (gaim)
JP7505713B2 (ja) 2019-02-22 2024-06-25 ロヨラ メリーマウント ユニバーシティ アミロイドペプチドバリアント
AU2023403257A1 (en) 2022-12-02 2025-06-12 Alzheon, Inc. Methods for treating neurodegenerative disorders with tramiprosate
CN117343200B (zh) * 2023-12-04 2024-01-30 北京质肽生物医药科技有限公司 一种包含淀粉样核心多肽的融合蛋白、制备方法及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3941763A (en) 1975-03-28 1976-03-02 American Home Products Corporation PGlu-D-Met-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 and intermediates
US4215051A (en) 1979-08-29 1980-07-29 Standard Oil Company (Indiana) Formation, purification and recovery of phthalic anhydride
JP4046354B2 (ja) 1996-03-18 2008-02-13 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 増大した半減期を有する免疫グロブリン様ドメイン
US8022270B2 (en) 2000-07-31 2011-09-20 Biolex Therapeutics, Inc. Expression of biologically active polypeptides in duckweed
US7083784B2 (en) 2000-12-12 2006-08-01 Medimmune, Inc. Molecules with extended half-lives, compositions and uses thereof
US7217797B2 (en) 2002-10-15 2007-05-15 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
WO2005037867A1 (en) 2003-10-15 2005-04-28 Pdl Biopharma, Inc. ALTERATION OF Fc-FUSION PROTEIN SERUM HALF-LIVES BY MUTAGENESIS OF POSITIONS 250, 314 AND/OR 428 OF THE HEAVY CHAIN CONSTANT REGION OF IG
CA2857539C (en) 2011-11-29 2021-08-03 Neurophage Pharmaceuticals, Inc. Bacteriophage gene 3 protein compositions and use as amyloid binding agents
DK2906235T3 (en) 2012-10-02 2017-09-25 Proclara Biosciences Inc USE OF P3 OF BACTERIOPHAGIC FUSION PROTEINS AS AMYLOID BINDING AGENTS
AU2014274253B2 (en) 2013-05-28 2018-06-14 Proclara Biosciences, Inc. Polypeptides comprising a modified bacteriophage g3p amino acid sequence with reduced immunogenicity
BR112017011530A2 (pt) 2014-12-03 2018-03-13 Proclara Biosciences Inc polipeptídeos que compreendem uma sequência de aminoácidos g3p de bacteriófago modificada sem sinal de glicosilação
WO2019241628A1 (en) * 2018-06-15 2019-12-19 Proclara Biosciences, Inc. General amyloid interaction motif (gaim)

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