JP2021527099A5 - - Google Patents

Info

Publication number
JP2021527099A5
JP2021527099A5 JP2020569188A JP2020569188A JP2021527099A5 JP 2021527099 A5 JP2021527099 A5 JP 2021527099A5 JP 2020569188 A JP2020569188 A JP 2020569188A JP 2020569188 A JP2020569188 A JP 2020569188A JP 2021527099 A5 JP2021527099 A5 JP 2021527099A5
Authority
JP
Japan
Prior art keywords
methyl
isoxazole
pyridazin
methylpyridine
pyridazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020569188A
Other languages
English (en)
Japanese (ja)
Other versions
JP7478676B2 (ja
JP2021527099A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2019/065129 external-priority patent/WO2019238633A1/en
Publication of JP2021527099A publication Critical patent/JP2021527099A/ja
Publication of JP2021527099A5 publication Critical patent/JP2021527099A5/ja
Application granted granted Critical
Publication of JP7478676B2 publication Critical patent/JP7478676B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020569188A 2018-06-13 2019-06-11 Ｇａｂａ ａ ａｌｐｈａ５ ｐａｍとしての新規イソオキサゾリルエーテル誘導体 Active JP7478676B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP18177522.2 2018-06-13
EP18177522 2018-06-13
EP18177825.9 2018-06-14
EP18177825 2018-06-14
PCT/EP2019/065129 WO2019238633A1 (en) 2018-06-13 2019-06-11 New isoxazolyl ether derivatives as gaba a alpha5 pam

Publications (3)

Publication Number Publication Date
JP2021527099A JP2021527099A (ja) 2021-10-11
JP2021527099A5 true JP2021527099A5 (cg-RX-API-DMAC7.html) 2022-06-13
JP7478676B2 JP7478676B2 (ja) 2024-05-07

Family

ID=66776367

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020569188A Active JP7478676B2 (ja) 2018-06-13 2019-06-11 Ｇａｂａ ａ ａｌｐｈａ５ ｐａｍとしての新規イソオキサゾリルエーテル誘導体

Country Status (18)

Country Link
US (1) US11840528B2 (cg-RX-API-DMAC7.html)
EP (1) EP3807269A1 (cg-RX-API-DMAC7.html)
JP (1) JP7478676B2 (cg-RX-API-DMAC7.html)
KR (1) KR20210021019A (cg-RX-API-DMAC7.html)
CN (1) CN112424196A (cg-RX-API-DMAC7.html)
AU (1) AU2019286312B2 (cg-RX-API-DMAC7.html)
BR (1) BR112020025355A2 (cg-RX-API-DMAC7.html)
CA (1) CA3102101A1 (cg-RX-API-DMAC7.html)
CL (1) CL2020003214A1 (cg-RX-API-DMAC7.html)
CR (1) CR20200610A (cg-RX-API-DMAC7.html)
IL (1) IL279266B2 (cg-RX-API-DMAC7.html)
MA (1) MA52868A (cg-RX-API-DMAC7.html)
MX (1) MX2020013518A (cg-RX-API-DMAC7.html)
PE (1) PE20210555A1 (cg-RX-API-DMAC7.html)
PH (1) PH12020500674A1 (cg-RX-API-DMAC7.html)
SG (1) SG11202012200QA (cg-RX-API-DMAC7.html)
TW (1) TWI816812B (cg-RX-API-DMAC7.html)
WO (1) WO2019238633A1 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI901650B (zh) 2020-03-26 2025-10-21 匈牙利商羅特格登公司 啶及吡啶并〔３，４－ｃ〕嗒衍生物
CN115461337A (zh) * 2020-05-13 2022-12-09 豪夫迈·罗氏有限公司 作为GABA A α5 PAM的新型三唑基衍生物
HU231691B1 (hu) 2021-09-29 2025-10-28 Richter Gedeon Nyrt GABAA ALFA5 receptor modulátor hatású biciklusos aminszármazékok
JP2026009006A (ja) * 2024-07-01 2026-01-19 日本たばこ産業株式会社 ピリダジノン化合物及びその医薬用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2682301A1 (en) * 2007-04-18 2008-10-30 Astrazeneca Ab Xanthine compounds having a positive allosteric gabab receptor modulator effect
UA100132C2 (en) * 2007-12-04 2012-11-26 Ф. Хоффманн-Ля Рош Аг Isoxazolo-pyridine derivatives
US7943619B2 (en) 2007-12-04 2011-05-17 Hoffmann-La Roche Inc. Isoxazolo-pyridazine derivatives
CA2724842A1 (en) 2008-05-19 2009-11-26 Sunovion Pharmaceuticals Inc. Imidazo[1,2-a]pyridine compounds
AU2010244552A1 (en) * 2009-05-05 2011-09-29 F. Hoffmann-La Roche Ag Isoxazole-pyrazole derivatives
US8604062B2 (en) 2011-10-20 2013-12-10 Hoffman-La Roche Inc. Process for the preparation of isoxazolyl-methoxy nicotinic acids
US8785435B2 (en) 2011-10-20 2014-07-22 Hoffmann-La Roche Inc. Solid forms
ES2910110T3 (es) 2016-12-08 2022-05-11 Hoffmann La Roche Nuevos derivados de isoxazolil-éter como PAM de alfa 5 GABA A

Similar Documents

Publication Publication Date Title
RU2473549C2 (ru) Пиримидиновые соединения, композиции и способы применения
JP2021527099A5 (cg-RX-API-DMAC7.html)
JP2021519291A5 (cg-RX-API-DMAC7.html)
JP2015522002A5 (cg-RX-API-DMAC7.html)
JP2025533831A (ja) Ｋｒａｓ ｇ１２ｃ変異タンパク質のテザー型複素環式阻害剤及びその使用
JP2014506929A5 (cg-RX-API-DMAC7.html)
RU2016135637A (ru) 6-гетероарилокси- и 6-арилоксихинолин-2-карбоксамиды и их применение
RU2018142987A (ru) Положительные аллостерические модуляторы мускаринового ацетилхолинового рецептора m4
JP2018500376A5 (cg-RX-API-DMAC7.html)
RU2019115115A (ru) Производные пиперидина в качестве ингибиторов убиквитин-специфической протеазы 7
JP2019535664A5 (cg-RX-API-DMAC7.html)
WO2017004500A9 (en) Bicyclic lactams and methods of use thereof
JP2014534976A5 (cg-RX-API-DMAC7.html)
JP2021504380A5 (cg-RX-API-DMAC7.html)
JP2021521165A5 (cg-RX-API-DMAC7.html)
JP2017505327A5 (cg-RX-API-DMAC7.html)
IL306126A (en) Heterocyclic compounds
JP2016525092A5 (cg-RX-API-DMAC7.html)
JP2015537010A5 (cg-RX-API-DMAC7.html)
US11840528B2 (en) Isoxazolyl ether derivatives as GABAA α5 PAM
KR20190088485A (ko) Gaba a 알파5 pam으로서 신규한 이소옥사졸릴 에터 유도체
HRP20250272T1 (hr) Derivati benzimidazola i njihova uporaba
JP2024511841A5 (cg-RX-API-DMAC7.html)
JP2024518811A (ja) カルボニル置換ジアザスピロ化合物及びその使用
JP2022508523A5 (cg-RX-API-DMAC7.html)