JP2021525265A5 - - Google Patents

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Publication number
JP2021525265A5
JP2021525265A5 JP2020565857A JP2020565857A JP2021525265A5 JP 2021525265 A5 JP2021525265 A5 JP 2021525265A5 JP 2020565857 A JP2020565857 A JP 2020565857A JP 2020565857 A JP2020565857 A JP 2020565857A JP 2021525265 A5 JP2021525265 A5 JP 2021525265A5
Authority
JP
Japan
Prior art keywords
formula
group
alkyl
methyl
composite according
Prior art date
Application number
JP2020565857A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021525265A (ja
JPWO2019224340A5 (https=
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2019/063423 external-priority patent/WO2019224340A1/en
Publication of JP2021525265A publication Critical patent/JP2021525265A/ja
Publication of JP2021525265A5 publication Critical patent/JP2021525265A5/ja
Publication of JPWO2019224340A5 publication Critical patent/JPWO2019224340A5/ja
Pending legal-status Critical Current

Links

JP2020565857A 2018-05-25 2019-05-24 ピロロベンゾジアゼピン複合体 Pending JP2021525265A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862676407P 2018-05-25 2018-05-25
US62/676,407 2018-05-25
PCT/EP2019/063423 WO2019224340A1 (en) 2018-05-25 2019-05-24 Pyrrolobenzodiazepine conjugates

Publications (3)

Publication Number Publication Date
JP2021525265A JP2021525265A (ja) 2021-09-24
JP2021525265A5 true JP2021525265A5 (https=) 2022-05-31
JPWO2019224340A5 JPWO2019224340A5 (https=) 2022-05-31

Family

ID=66677112

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020565857A Pending JP2021525265A (ja) 2018-05-25 2019-05-24 ピロロベンゾジアゼピン複合体

Country Status (5)

Country Link
US (1) US20210283141A1 (https=)
EP (1) EP3801630A1 (https=)
JP (1) JP2021525265A (https=)
CN (1) CN112203696A (https=)
WO (1) WO2019224340A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7168780B2 (ja) 2018-12-12 2022-11-09 ヘレウス マテリアルズ シンガポール ピーティーイー． リミテッド 電子部品の接触面を電気的に接続するプロセス
GB202105187D0 (en) 2021-04-12 2021-05-26 Medimmune Ltd Pyrrolobenzodiazepine conjugates
GB202105186D0 (en) 2021-04-12 2021-05-26 Medimmune Ltd Pyrrolobenzodiazepine conjugates
KR20250031149A (ko) 2022-06-30 2025-03-06 도레이 카부시키가이샤 암의 치료 및/또는 예방용 의약 조성물

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58180487A (ja) 1982-04-16 1983-10-21 Kyowa Hakko Kogyo Co Ltd 抗生物質ｄｃ−８１およびその製造法
DE69930328T2 (de) 1998-08-27 2006-12-14 Spirogen Ltd., Ryde Dimere Pyrrolobenzodiazepine
GB0226593D0 (en) 2002-11-14 2002-12-24 Consultants Ltd Compounds
GB0321295D0 (en) 2003-09-11 2003-10-15 Spirogen Ltd Synthesis of protected pyrrolobenzodiazepines
SI2270010T1 (sl) 2004-03-01 2012-05-31 Spirogen Ltd hidroksi H pirolo c benzodiazepin onski derivati kot ključni intermediati za pripravo C substituiranih pirolobenzodiazepinov
PL1879901T3 (pl) 2005-04-21 2010-06-30 Medimmune Ltd Pirolobenzodiazepiny
SI1813614T1 (sl) 2006-01-25 2012-01-31 Sanofi 174 Citotoksična sredstva, ki obsegajo nove tomajmicinske derivate
EP3006425A1 (en) * 2007-04-23 2016-04-13 Siga Technologies, Inc. Pharmaceutical composition for use in the treatment and prevention of orthopoxvirus infections and associated diseases
DK2528625T3 (da) 2010-04-15 2013-10-14 Spirogen Sarl Pyrrolobenzodiazepiner og konjugater deraf
WO2012064733A2 (en) 2010-11-09 2012-05-18 Medimmune, Llc Antibody scaffold for homogenous conjugation
CN104837502B (zh) * 2012-10-12 2018-08-10 麦迪穆有限责任公司 吡咯并苯并二氮杂卓及其结合物
US10751346B2 (en) * 2012-10-12 2020-08-25 Medimmune Limited Pyrrolobenzodiazepine—anti-PSMA antibody conjugates
CN105189507A (zh) * 2012-12-21 2015-12-23 斯皮罗根有限公司 吡咯并苯并二氮杂卓及其结合物
GB201317982D0 (en) * 2013-10-11 2013-11-27 Spirogen Sarl Pyrrolobenzodiazepines and conjugates thereof
GB201506389D0 (en) * 2015-04-15 2015-05-27 Berkel Patricius H C Van And Howard Philip W Site-specific antibody-drug conjugates
PE20181302A1 (es) * 2015-12-04 2018-08-09 Abbvie Stemcentrx Llc Nuevos anticuerpos anti-claudina y sus metodos de uso
GB201607478D0 (en) 2016-04-29 2016-06-15 Medimmune Ltd Pyrrolobenzodiazepine Conjugates
GB201617466D0 (en) 2016-10-14 2016-11-30 Medimmune Ltd Pyrrolobenzodiazepine conjugates
AR111963A1 (es) * 2017-05-26 2019-09-04 Univ California Método y moléculas

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