JP2021525100A5 - - Google Patents

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JP2021525100A5
JP2021525100A5 JP2021514482A JP2021514482A JP2021525100A5 JP 2021525100 A5 JP2021525100 A5 JP 2021525100A5 JP 2021514482 A JP2021514482 A JP 2021514482A JP 2021514482 A JP2021514482 A JP 2021514482A JP 2021525100 A5 JP2021525100 A5 JP 2021525100A5
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JP
Japan
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JP2021514482A
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JP2021525100A (ja
JP7530886B2 (ja
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Priority claimed from PCT/EP2019/062649 external-priority patent/WO2019219828A1/en
Publication of JP2021525100A publication Critical patent/JP2021525100A/ja
Publication of JP2021525100A5 publication Critical patent/JP2021525100A5/ja
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JP2021514482A 2018-05-16 2019-05-16 増殖性肝細胞を培養する方法 Active JP7530886B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18305603.5 2018-05-16
EP18305603 2018-05-16
PCT/EP2019/062649 WO2019219828A1 (en) 2018-05-16 2019-05-16 Method of culturing proliferative hepatocytes

Publications (3)

Publication Number Publication Date
JP2021525100A JP2021525100A (ja) 2021-09-24
JP2021525100A5 true JP2021525100A5 (ja) 2021-11-04
JP7530886B2 JP7530886B2 (ja) 2024-08-08

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021514482A Active JP7530886B2 (ja) 2018-05-16 2019-05-16 増殖性肝細胞を培養する方法

Country Status (5)

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US (1) US20210189346A1 (ja)
EP (1) EP3794107A1 (ja)
JP (1) JP7530886B2 (ja)
CN (1) CN112513252B (ja)
WO (1) WO2019219828A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220396773A1 (en) * 2019-11-15 2022-12-15 INSERM (Institut National de la Santé et de la Recherche Médicale) Method of culturing immortalized human hepatic progenitors or cells
CN113667642A (zh) * 2020-05-15 2021-11-19 北京大橡科技有限公司 3d人肝器官模型构建方法、3d人肝器官模型及其应用
BE1028324B1 (nl) 2020-05-19 2021-12-22 Rousselot Ge(meth)acryleerd gelatine laag in endotoxines
CN113151151B (zh) * 2021-05-07 2023-05-30 南京鼓楼医院 一种iPSC来源肝细胞的仿生微球大规模培养的方法及应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60236974D1 (de) 2001-07-26 2010-08-19 Transparent Inc Kultiviertes Zellkonstrukt mit Sphäroiden kultivierter Tierzellen und seine Verwendung
US20050244959A1 (en) 2004-03-30 2005-11-03 Anne Corlu Methods for inducing active hepatocytes proliferation, kits using such methods and uses of said kits
EP1815244A4 (en) 2004-11-11 2009-07-22 Agency Science Tech & Res DEVICE FOR CULTURING CELLS
US20100143313A1 (en) * 2008-12-10 2010-06-10 The General Hospital Corporation Homogeneous differentiation of hepatocyte-like cells from embryonic stem cells
DE102011121317A1 (de) 2011-12-16 2013-06-20 Universitätsklinikum Hamburg-Eppendorf Gerüstfreie Leberzellaggregate zur Verwendung bei der Transplantation
EA034878B1 (ru) * 2013-08-28 2020-04-01 Прометера Байосайенсиз С.А./Н.В. Способ получения клеток-предшественников зрелой печени
CN105296418B (zh) * 2014-08-04 2019-01-18 上海赛立维生物科技有限公司 一种长期体外培养和扩增肝细胞的方法及其应用
KR20190003833A (ko) * 2014-08-28 2019-01-09 프로메테라 바이오사이언시즈 에스.에이./엔.브이. 성체 간 전구 세포의 제조 방법
HUE041518T2 (hu) * 2015-02-20 2019-05-28 Inst Nat Sante Rech Med Laminin alkalmazása pluripotens sejtek hepatocita sejtvonalhoz tartozó sejtekké történõ differenciálódásához
WO2016185281A1 (en) * 2015-05-20 2016-11-24 Biopredic International New hepatic cell lines and methods of making and using the same
WO2017150294A1 (ja) 2016-03-04 2017-09-08 良考 山口 多能性幹細胞様スフェロイドの製造方法および多能性幹細胞様スフェロイド
EP3940059A1 (en) 2016-08-25 2022-01-19 Philip Morris Products S.A. Cell culture
KR101837293B1 (ko) * 2016-09-09 2018-04-19 인하대학교 산학협력단 인간 타액선 세포 기반 3차원 체외 배양을 통한 선 조직 유사 오가노이드 형성 방법 및 이를 이용한 타액선 질환 모델의 용도

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