JP2021523739A5 - - Google Patents
Info
- Publication number
- JP2021523739A5 JP2021523739A5 JP2021513765A JP2021513765A JP2021523739A5 JP 2021523739 A5 JP2021523739 A5 JP 2021523739A5 JP 2021513765 A JP2021513765 A JP 2021513765A JP 2021513765 A JP2021513765 A JP 2021513765A JP 2021523739 A5 JP2021523739 A5 JP 2021523739A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- rtt
- mecp2
- base editor
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024095566A JP2024138268A (ja) | 2018-05-11 | 2024-06-13 | プログラム可能な塩基エディターシステムを用いて単一ヌクレオチド多型を編集する方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862670588P | 2018-05-11 | 2018-05-11 | |
| US62/670,588 | 2018-05-11 | ||
| US201862780838P | 2018-12-17 | 2018-12-17 | |
| US62/780,838 | 2018-12-17 | ||
| US201962817986P | 2019-03-13 | 2019-03-13 | |
| US62/817,986 | 2019-03-13 | ||
| PCT/US2019/031899 WO2019217944A1 (en) | 2018-05-11 | 2019-05-11 | Methods of editing single nucleotide polymorphism using programmable base editor systems |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024095566A Division JP2024138268A (ja) | 2018-05-11 | 2024-06-13 | プログラム可能な塩基エディターシステムを用いて単一ヌクレオチド多型を編集する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021523739A JP2021523739A (ja) | 2021-09-09 |
| JP2021523739A5 true JP2021523739A5 (https=) | 2022-05-19 |
| JP7596259B2 JP7596259B2 (ja) | 2024-12-09 |
Family
ID=68466849
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021513765A Active JP7596259B2 (ja) | 2018-05-11 | 2019-05-11 | プログラム可能な塩基エディターシステムを用いて単一ヌクレオチド多型を編集する方法 |
| JP2021513764A Pending JP2021523738A (ja) | 2018-05-11 | 2019-05-11 | プログラム可能な塩基エディターシステムを使用して単一ヌクレオチド多型を編集する方法 |
| JP2024095618A Pending JP2024147545A (ja) | 2018-05-11 | 2024-06-13 | プログラム可能な塩基エディターシステムを使用して単一ヌクレオチド多型を編集する方法 |
| JP2024095566A Pending JP2024138268A (ja) | 2018-05-11 | 2024-06-13 | プログラム可能な塩基エディターシステムを用いて単一ヌクレオチド多型を編集する方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021513764A Pending JP2021523738A (ja) | 2018-05-11 | 2019-05-11 | プログラム可能な塩基エディターシステムを使用して単一ヌクレオチド多型を編集する方法 |
| JP2024095618A Pending JP2024147545A (ja) | 2018-05-11 | 2024-06-13 | プログラム可能な塩基エディターシステムを使用して単一ヌクレオチド多型を編集する方法 |
| JP2024095566A Pending JP2024138268A (ja) | 2018-05-11 | 2024-06-13 | プログラム可能な塩基エディターシステムを用いて単一ヌクレオチド多型を編集する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20230159956A1 (https=) |
| EP (2) | EP3790963A4 (https=) |
| JP (4) | JP7596259B2 (https=) |
| KR (2) | KR20250133482A (https=) |
| CN (3) | CN119587720A (https=) |
| AU (2) | AU2019266327B2 (https=) |
| CA (2) | CA3100034A1 (https=) |
| WO (2) | WO2019217944A1 (https=) |
Families Citing this family (67)
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| KR20230156800A (ko) | 2015-03-03 | 2023-11-14 | 더 제너럴 하스피탈 코포레이션 | 변경된 PAM 특이성을 갖는 조작된 CRISPR-Cas9 뉴클레아제 |
| CN110612353A (zh) | 2017-03-03 | 2019-12-24 | 加利福尼亚大学董事会 | 经由抑制性tRNAs和脱氨酶对突变进行RNA靶向 |
| EP3592853A1 (en) | 2017-03-09 | 2020-01-15 | President and Fellows of Harvard College | Suppression of pain by gene editing |
| WO2018221685A1 (ja) | 2017-05-31 | 2018-12-06 | 国立大学法人 東京大学 | 改変されたＣａｓ９タンパク質及びその用途 |
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| WO2022150651A1 (en) * | 2021-01-07 | 2022-07-14 | The Broad Institute, Inc. | Dna nuclease guided transposase compositions and methods of use thereof |
| EP4308702A4 (en) * | 2021-03-15 | 2025-03-05 | Duke University | GENERATING NEW CRISPR GENOME-EDITING AGENTS USING COMBINATORY CHEMISTRY |
| AU2022272250A1 (en) * | 2021-05-14 | 2023-11-30 | Beam Therapeutics Inc. | Compositions and methods for treating transthyretin amyloidosis |
| WO2022246266A1 (en) * | 2021-05-21 | 2022-11-24 | Beam Therapeutics Inc. | Base editing of transthyretin gene |
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-
2019
- 2019-05-11 KR KR1020257028616A patent/KR20250133482A/ko active Pending
- 2019-05-11 EP EP19799484.1A patent/EP3790963A4/en active Pending
- 2019-05-11 AU AU2019266327A patent/AU2019266327B2/en active Active
- 2019-05-11 US US17/054,348 patent/US20230159956A1/en active Pending
- 2019-05-11 KR KR1020207035001A patent/KR102853088B1/ko active Active
- 2019-05-11 JP JP2021513765A patent/JP7596259B2/ja active Active
- 2019-05-11 CN CN202411723844.9A patent/CN119587720A/zh active Pending
- 2019-05-11 CN CN201980046479.3A patent/CN112469446B/zh active Active
- 2019-05-11 CA CA3100034A patent/CA3100034A1/en active Pending
- 2019-05-11 US US17/054,324 patent/US20210380955A1/en active Pending
- 2019-05-11 CN CN201980046538.7A patent/CN112469824A/zh active Pending
- 2019-05-11 CA CA3100037A patent/CA3100037A1/en active Pending
- 2019-05-11 EP EP19799854.5A patent/EP3790595A4/en active Pending
- 2019-05-11 WO PCT/US2019/031899 patent/WO2019217944A1/en not_active Ceased
- 2019-05-11 WO PCT/US2019/031898 patent/WO2019217943A1/en not_active Ceased
- 2019-05-11 JP JP2021513764A patent/JP2021523738A/ja active Pending
- 2019-05-11 AU AU2019266326A patent/AU2019266326B2/en active Active
-
2024
- 2024-06-13 JP JP2024095618A patent/JP2024147545A/ja active Pending
- 2024-06-13 JP JP2024095566A patent/JP2024138268A/ja active Pending
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