JP2021523712A - 安定性が改善された遺伝子組み換え組換えワクシニアアンカラ(rmva)ワクチン及びその調製方法 - Google Patents

安定性が改善された遺伝子組み換え組換えワクシニアアンカラ(rmva)ワクチン及びその調製方法 Download PDF

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JP2021523712A
JP2021523712A JP2020563659A JP2020563659A JP2021523712A JP 2021523712 A JP2021523712 A JP 2021523712A JP 2020563659 A JP2020563659 A JP 2020563659A JP 2020563659 A JP2020563659 A JP 2020563659A JP 2021523712 A JP2021523712 A JP 2021523712A
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ウッスロー,フェリックス
ジェイ. ダイアモンド,ドン
ジェイ. ダイアモンド,ドン
コントレラス,ハイディ
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City of Hope
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JP2020563659A 2018-05-11 2019-05-10 安定性が改善された遺伝子組み換え組換えワクシニアアンカラ(rmva)ワクチン及びその調製方法 Pending JP2021523712A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862670656P 2018-05-11 2018-05-11
US62/670,656 2018-05-11
PCT/US2019/031866 WO2019217922A1 (en) 2018-05-11 2019-05-10 Genetically modified recombinant vaccinia ankara (rmva) vaccines of improved stability and methods of preparation thereof

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JP2021523712A true JP2021523712A (ja) 2021-09-09
JPWO2019217922A5 JPWO2019217922A5 (https=) 2022-05-18
JP2021523712A5 JP2021523712A5 (https=) 2022-05-18

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US (1) US12054736B2 (https=)
EP (1) EP3790578A4 (https=)
JP (1) JP2021523712A (https=)
CN (1) CN112512568A (https=)
WO (1) WO2019217922A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8580276B2 (en) 2009-06-05 2013-11-12 City Of Hope Genetically stable recombinant modified vaccinia ankara (rMVA) vaccines and methods of preparation thereof
EP3529353A4 (en) 2016-10-19 2020-05-13 City of Hope USE OF TRIPLEX-CMV VACCINE IN CAR-T-CELL THERAPY
KR20250005247A (ko) 2022-04-13 2025-01-09 시티 오브 호프 Cmv-hiv 특이적 키메라 항원 수용체 t 세포
WO2025184598A1 (en) * 2024-03-01 2025-09-04 City Of Hope Stable and immunogenic cmv vaccine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100316667A1 (en) * 2009-06-05 2010-12-16 Don Diamond Genetically stable recombinant modified vaccinia ankara (rmva) vaccines and methods of preparation thereof

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
US6835383B2 (en) 2000-03-23 2004-12-28 City Of Hope Protein kinase deficient, immunologically active CMVpp65 mutants
CN102703393A (zh) 2002-05-16 2012-10-03 巴法里安诺迪克有限公司 表达插入痘病毒基因组中的同源基因的重组痘病毒
US7501127B2 (en) * 2002-05-16 2009-03-10 Bavarian Nordic A/S Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara
US7163685B2 (en) 2003-04-16 2007-01-16 City Of Hope Human cytomegalovirus antigens expressed in MVA and methods of use
US8326547B2 (en) * 2009-10-07 2012-12-04 Nanjingjinsirui Science & Technology Biology Corp. Method of sequence optimization for improved recombinant protein expression using a particle swarm optimization algorithm
WO2011047324A1 (en) 2009-10-16 2011-04-21 The U.S.A. As Represented By The Secretary , Department Of Health And Human Services . Recombinant modified vaccinia ankara (mva) vaccinia virus containing restructured insertion sites
JP2013544504A (ja) 2010-10-11 2013-12-19 ノバルティス アーゲー 抗原送達プラットフォーム
DK2877580T3 (en) 2012-07-27 2019-04-23 Hope City VAT VACCINE TO DELIVER A UL128 COMPLEX AND PREVENT CMV INFECTION
WO2018075813A1 (en) * 2016-10-19 2018-04-26 City Of Hope Use of endogenous viral vaccine in chimeric antigen receptor t cell therapy

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100316667A1 (en) * 2009-06-05 2010-12-16 Don Diamond Genetically stable recombinant modified vaccinia ankara (rmva) vaccines and methods of preparation thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BLOOD, 2017, VOL.129, NO.1, PP.114-125, JPN6023016830, ISSN: 0005210859 *
VACCINE, 2010, VOL.28, PP.1547-1557, JPN6023016831, ISSN: 0005210860 *
VIROLOGY, 2010, VOL.403, PP.155-162, JPN6023016829, ISSN: 0005210861 *

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EP3790578A4 (en) 2022-04-06
CN112512568A (zh) 2021-03-16
WO2019217922A1 (en) 2019-11-14
US20210062221A1 (en) 2021-03-04
EP3790578A1 (en) 2021-03-17
US12054736B2 (en) 2024-08-06

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