JP2021523712A - 安定性が改善された遺伝子組み換え組換えワクシニアアンカラ(rmva)ワクチン及びその調製方法 - Google Patents
安定性が改善された遺伝子組み換え組換えワクシニアアンカラ(rmva)ワクチン及びその調製方法 Download PDFInfo
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- JP2021523712A JP2021523712A JP2020563659A JP2020563659A JP2021523712A JP 2021523712 A JP2021523712 A JP 2021523712A JP 2020563659 A JP2020563659 A JP 2020563659A JP 2020563659 A JP2020563659 A JP 2020563659A JP 2021523712 A JP2021523712 A JP 2021523712A
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- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2800/00—Nucleic acids vectors
- C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
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- Communicable Diseases (AREA)
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- General Chemical & Material Sciences (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862670656P | 2018-05-11 | 2018-05-11 | |
| US62/670,656 | 2018-05-11 | ||
| PCT/US2019/031866 WO2019217922A1 (en) | 2018-05-11 | 2019-05-10 | Genetically modified recombinant vaccinia ankara (rmva) vaccines of improved stability and methods of preparation thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021523712A true JP2021523712A (ja) | 2021-09-09 |
| JPWO2019217922A5 JPWO2019217922A5 (https=) | 2022-05-18 |
| JP2021523712A5 JP2021523712A5 (https=) | 2022-05-18 |
Family
ID=68467105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020563659A Pending JP2021523712A (ja) | 2018-05-11 | 2019-05-10 | 安定性が改善された遺伝子組み換え組換えワクシニアアンカラ(rmva)ワクチン及びその調製方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US12054736B2 (https=) |
| EP (1) | EP3790578A4 (https=) |
| JP (1) | JP2021523712A (https=) |
| CN (1) | CN112512568A (https=) |
| WO (1) | WO2019217922A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8580276B2 (en) | 2009-06-05 | 2013-11-12 | City Of Hope | Genetically stable recombinant modified vaccinia ankara (rMVA) vaccines and methods of preparation thereof |
| EP3529353A4 (en) | 2016-10-19 | 2020-05-13 | City of Hope | USE OF TRIPLEX-CMV VACCINE IN CAR-T-CELL THERAPY |
| KR20250005247A (ko) | 2022-04-13 | 2025-01-09 | 시티 오브 호프 | Cmv-hiv 특이적 키메라 항원 수용체 t 세포 |
| WO2025184598A1 (en) * | 2024-03-01 | 2025-09-04 | City Of Hope | Stable and immunogenic cmv vaccine |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100316667A1 (en) * | 2009-06-05 | 2010-12-16 | Don Diamond | Genetically stable recombinant modified vaccinia ankara (rmva) vaccines and methods of preparation thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6835383B2 (en) | 2000-03-23 | 2004-12-28 | City Of Hope | Protein kinase deficient, immunologically active CMVpp65 mutants |
| CN102703393A (zh) | 2002-05-16 | 2012-10-03 | 巴法里安诺迪克有限公司 | 表达插入痘病毒基因组中的同源基因的重组痘病毒 |
| US7501127B2 (en) * | 2002-05-16 | 2009-03-10 | Bavarian Nordic A/S | Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara |
| US7163685B2 (en) | 2003-04-16 | 2007-01-16 | City Of Hope | Human cytomegalovirus antigens expressed in MVA and methods of use |
| US8326547B2 (en) * | 2009-10-07 | 2012-12-04 | Nanjingjinsirui Science & Technology Biology Corp. | Method of sequence optimization for improved recombinant protein expression using a particle swarm optimization algorithm |
| WO2011047324A1 (en) | 2009-10-16 | 2011-04-21 | The U.S.A. As Represented By The Secretary , Department Of Health And Human Services . | Recombinant modified vaccinia ankara (mva) vaccinia virus containing restructured insertion sites |
| JP2013544504A (ja) | 2010-10-11 | 2013-12-19 | ノバルティス アーゲー | 抗原送達プラットフォーム |
| DK2877580T3 (en) | 2012-07-27 | 2019-04-23 | Hope City | VAT VACCINE TO DELIVER A UL128 COMPLEX AND PREVENT CMV INFECTION |
| WO2018075813A1 (en) * | 2016-10-19 | 2018-04-26 | City Of Hope | Use of endogenous viral vaccine in chimeric antigen receptor t cell therapy |
-
2019
- 2019-05-10 EP EP19800357.6A patent/EP3790578A4/en not_active Withdrawn
- 2019-05-10 JP JP2020563659A patent/JP2021523712A/ja active Pending
- 2019-05-10 WO PCT/US2019/031866 patent/WO2019217922A1/en not_active Ceased
- 2019-05-10 CN CN201980046532.XA patent/CN112512568A/zh active Pending
-
2020
- 2020-11-11 US US17/095,300 patent/US12054736B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100316667A1 (en) * | 2009-06-05 | 2010-12-16 | Don Diamond | Genetically stable recombinant modified vaccinia ankara (rmva) vaccines and methods of preparation thereof |
Non-Patent Citations (3)
| Title |
|---|
| BLOOD, 2017, VOL.129, NO.1, PP.114-125, JPN6023016830, ISSN: 0005210859 * |
| VACCINE, 2010, VOL.28, PP.1547-1557, JPN6023016831, ISSN: 0005210860 * |
| VIROLOGY, 2010, VOL.403, PP.155-162, JPN6023016829, ISSN: 0005210861 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3790578A4 (en) | 2022-04-06 |
| CN112512568A (zh) | 2021-03-16 |
| WO2019217922A1 (en) | 2019-11-14 |
| US20210062221A1 (en) | 2021-03-04 |
| EP3790578A1 (en) | 2021-03-17 |
| US12054736B2 (en) | 2024-08-06 |
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