JP2021522865A - 栄養要求性調節可能な細胞を使用する遺伝子療法の方法および組成物 - Google Patents

栄養要求性調節可能な細胞を使用する遺伝子療法の方法および組成物 Download PDF

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JP2021522865A
JP2021522865A JP2021513376A JP2021513376A JP2021522865A JP 2021522865 A JP2021522865 A JP 2021522865A JP 2021513376 A JP2021513376 A JP 2021513376A JP 2021513376 A JP2021513376 A JP 2021513376A JP 2021522865 A JP2021522865 A JP 2021522865A
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auxotrophic
cells
cell
factor
host cell
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JP2021522865A5 (https=
JPWO2019217803A5 (https=
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ジェイムズ パターソン
ジェイムズ パターソン
マシュー ポルテウス
マシュー ポルテウス
フォルカー ウィービング
フォルカー ウィービング
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Leland Stanford Junior University
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    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
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    • A61K40/00—Cellular immunotherapy
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JP2021513376A 2018-05-10 2019-05-10 栄養要求性調節可能な細胞を使用する遺伝子療法の方法および組成物 Withdrawn JP2021522865A (ja)

Applications Claiming Priority (3)

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US201862669848P 2018-05-10 2018-05-10
US62/669,848 2018-05-10
PCT/US2019/031699 WO2019217803A1 (en) 2018-05-10 2019-05-10 Gene therapy methods and compositions using auxotrophic regulatable cells

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JP2021522865A true JP2021522865A (ja) 2021-09-02
JP2021522865A5 JP2021522865A5 (https=) 2022-05-17
JPWO2019217803A5 JPWO2019217803A5 (https=) 2022-05-17

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JP2021513376A Withdrawn JP2021522865A (ja) 2018-05-10 2019-05-10 栄養要求性調節可能な細胞を使用する遺伝子療法の方法および組成物

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US (1) US20210052741A1 (https=)
EP (1) EP3790974A1 (https=)
JP (1) JP2021522865A (https=)
KR (1) KR20210030902A (https=)
CN (1) CN112513271A (https=)
AU (1) AU2019265916A1 (https=)
BR (1) BR112020022612A2 (https=)
CA (1) CA3098874A1 (https=)
MX (1) MX2020011757A (https=)
SG (1) SG11202010837XA (https=)
WO (1) WO2019217803A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230265440A1 (en) * 2020-06-26 2023-08-24 The Board Of Trustees Of The Leland Stanford Junior University Targeting the human ccr5 locus as a safe harbor for the expression of therapeutic proteins
WO2025080701A1 (en) * 2023-10-11 2025-04-17 William Marsh Rice University Genetically activated mesenchymal stem cells and stromal cells

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030232430A1 (en) 2001-11-26 2003-12-18 Advanced Cell Technology Methods for making and using reprogrammed human somatic cell nuclei and autologous and isogenic human stem cells
CA2608913A1 (en) * 2005-05-18 2006-11-23 Biofactura, Inc. Compositions and methods for metabolic selection of transfected cells
US20090176260A1 (en) 2007-12-04 2009-07-09 Joseph Ching-Ming Wu Double-fusion human embryonic stem cells, methods of making double-fusion human embryonic stem cells, triple-fusion human embryonic stem cells, methods of making triple-fusion human embryonic stem cells, and methods of monitoring double-fusion human embryonic stem cells and triple-fusion human embryonic stem cells
EP3241902B1 (en) 2012-05-25 2018-02-28 The Regents of The University of California Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription
EP3363902B1 (en) 2012-12-06 2019-11-27 Sigma Aldrich Co. LLC Crispr-based genome modification and regulation
CA2894684A1 (en) 2012-12-12 2014-06-19 The Broad Institute, Inc. Engineering and optimization of improved crispr-cas systems, methods and enzyme compositions for sequence manipulation in eukaryotes
US20160122774A1 (en) 2013-05-29 2016-05-05 Cellectis A method for producing precise dna cleavage using cas9 nickase activity
US11319555B2 (en) * 2014-11-20 2022-05-03 Duke University Compositions, systems and methods for cell therapy
GB201618414D0 (en) * 2016-11-01 2016-12-14 Patterson James Regulated cell lines and methods of use thereof

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Publication number Publication date
MX2020011757A (es) 2021-01-08
SG11202010837XA (en) 2020-11-27
BR112020022612A2 (pt) 2021-02-09
CA3098874A1 (en) 2019-11-14
US20210052741A1 (en) 2021-02-25
CN112513271A (zh) 2021-03-16
WO2019217803A1 (en) 2019-11-14
AU2019265916A1 (en) 2020-12-10
EP3790974A1 (en) 2021-03-17
KR20210030902A (ko) 2021-03-18

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