JP2021522345A5 - - Google Patents

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Publication number
JP2021522345A5
JP2021522345A5 JP2021509963A JP2021509963A JP2021522345A5 JP 2021522345 A5 JP2021522345 A5 JP 2021522345A5 JP 2021509963 A JP2021509963 A JP 2021509963A JP 2021509963 A JP2021509963 A JP 2021509963A JP 2021522345 A5 JP2021522345 A5 JP 2021522345A5
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JP
Japan
Prior art keywords
pharmaceutical composition
composition according
cancer
subject
administering
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Granted
Application number
JP2021509963A
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English (en)
Japanese (ja)
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JP7115671B2 (ja
JP2021522345A (ja
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Priority claimed from PCT/US2019/029192 external-priority patent/WO2020033019A2/en
Publication of JP2021522345A publication Critical patent/JP2021522345A/ja
Publication of JP2021522345A5 publication Critical patent/JP2021522345A5/ja
Application granted granted Critical
Publication of JP7115671B2 publication Critical patent/JP7115671B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021509963A 2018-04-25 2019-04-25 新規なmct4阻害剤及びその使用 Active JP7115671B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862662637P 2018-04-25 2018-04-25
US62/662,637 2018-04-25
PCT/US2019/029192 WO2020033019A2 (en) 2018-04-25 2019-04-25 Novel mct4 inhibitors and uses thereof

Publications (3)

Publication Number Publication Date
JP2021522345A JP2021522345A (ja) 2021-08-30
JP2021522345A5 true JP2021522345A5 (OSRAM) 2022-04-28
JP7115671B2 JP7115671B2 (ja) 2022-08-09

Family

ID=68532786

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021509963A Active JP7115671B2 (ja) 2018-04-25 2019-04-25 新規なmct4阻害剤及びその使用

Country Status (7)

Country Link
US (1) US10919878B2 (OSRAM)
EP (1) EP3784650B1 (OSRAM)
JP (1) JP7115671B2 (OSRAM)
CN (1) CN112888673B (OSRAM)
AU (1) AU2019317518B2 (OSRAM)
CA (1) CA3098189C (OSRAM)
WO (1) WO2020033019A2 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12544375B2 (en) * 2019-09-05 2026-02-10 The Board Of Trustees Of The Leland Junior University Small molecule therapeutic for parkinson's disease paired with a biomarker of therapeutic activity
WO2021249969A1 (en) * 2020-06-10 2021-12-16 Merck Patent Gmbh Combination product for the treatment of cancer diseases
US20240270749A1 (en) 2021-05-21 2024-08-15 Cemm - Forschungszentrum Für Molekulare Medizin Gmbh 1,2,4-triazolo[1,5-a]pyrimidine-based slc16a3 inhibitors and their therapeutic use
WO2022243574A1 (en) 2021-05-21 2022-11-24 Cemm - Forschungszentrum Für Molekulare Medizin Gmbh 3-(phthalazin-1-yl)benzenesulfonamide-based slc16a3 inhibitors and their therapeutic use

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226438A (OSRAM) 1968-12-03 1971-03-31
GB0327734D0 (en) * 2003-11-28 2003-12-31 Novartis Ag Organic compounds
TW200804349A (en) * 2005-12-23 2008-01-16 Kalypsys Inc Novel substituted pyrimidinyloxy ureas as inhibitors of protein kinases
WO2010089580A1 (en) * 2009-02-06 2010-08-12 Astrazeneca Ab Use of a mct1 inhibitor in the treatment of cancers expressing mct1 over mct4
CN102731413A (zh) * 2011-04-15 2012-10-17 上海医药工业研究院 一种脲类化合物、其制备方法、其中间体及其应用
WO2014189152A1 (en) 2013-05-24 2014-11-27 Otsuka Pharmaceutical Co., Ltd. Pharmaceutical combination comprising metformin and dihydroquercetin and its use for the treatment of cancer
JP2017538689A (ja) 2014-11-17 2017-12-28 ニーロジョン セラピューティクス インコーポレイテッドNirogyone Therapeutics, Inc. モノカルボン酸輸送修飾薬およびその使用
WO2016118822A1 (en) * 2015-01-22 2016-07-28 The Scripps Research Institute Chromenone inhibitors of monocarboxylate transporters
WO2016118823A1 (en) 2015-01-22 2016-07-28 The Scripps Research Institute Pteridine dione monocarboxylate transporter inhibitors
AU2016277126A1 (en) * 2015-06-12 2017-12-14 Vettore, LLC MCT4 inhibitors for treating disease
AU2017444054B2 (en) * 2017-12-21 2021-10-07 Hefei Institutes Of Physical Science, Chinese Academy Of Sciences Class of pyrimidine derivative kinase inhibitors

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