JP2021520815A5 - - Google Patents
Info
- Publication number
- JP2021520815A5 JP2021520815A5 JP2020555861A JP2020555861A JP2021520815A5 JP 2021520815 A5 JP2021520815 A5 JP 2021520815A5 JP 2020555861 A JP2020555861 A JP 2020555861A JP 2020555861 A JP2020555861 A JP 2020555861A JP 2021520815 A5 JP2021520815 A5 JP 2021520815A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid sequence
- polymerase variant
- rna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862655747P | 2018-04-10 | 2018-04-10 | |
| US62/655,747 | 2018-04-10 | ||
| PCT/US2019/026561 WO2019199807A1 (en) | 2018-04-10 | 2019-04-09 | T7 rna polymerase variants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021520815A JP2021520815A (ja) | 2021-08-26 |
| JP2021520815A5 true JP2021520815A5 (https=) | 2022-04-14 |
Family
ID=66248824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020555861A Withdrawn JP2021520815A (ja) | 2018-04-10 | 2019-04-09 | Ｔ７ｒｎａポリメラーゼバリアント |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210180034A1 (https=) |
| EP (1) | EP3775183A1 (https=) |
| JP (1) | JP2021520815A (https=) |
| CN (1) | CN112218947A (https=) |
| AU (1) | AU2019253693A1 (https=) |
| CA (1) | CA3095620A1 (https=) |
| WO (1) | WO2019199807A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4150067A2 (en) | 2020-05-11 | 2023-03-22 | Thermo Fisher Scientific Baltics Uab | Mutant polymerases and methods of using the same |
| CN112980811B (zh) * | 2021-03-06 | 2022-02-25 | 苏州瀚源新酶生物科技有限公司 | Rna聚合酶突变体及其应用、重组载体及其制备方法和应用、重组工程菌及其应用 |
| JP2025078889A (ja) * | 2022-02-03 | 2025-05-21 | 天野エンザイム株式会社 | 酵素製剤 |
| CN120082531A (zh) * | 2023-12-28 | 2025-06-03 | 翌圣生物科技(上海)股份有限公司 | T7 rna聚合酶突变体及其应用 |
| US12492420B2 (en) | 2024-03-29 | 2025-12-09 | New England Biolabs, Inc. | Compositions, kits, and methods for in vitro transcription |
| GB202406294D0 (en) | 2024-05-06 | 2024-06-19 | Thermo Fisher Scientific Baltics Uab | Methods and compositions for producing capped mRNA |
| CN118374471A (zh) * | 2024-05-08 | 2024-07-23 | 珍奥集团股份有限公司 | 一种不产生免疫原性副产物、具备高转录活性的t7 rna聚合酶突变体与应用 |
| CN121160664B (zh) * | 2024-06-17 | 2026-04-24 | 南京诺唯赞生物科技股份有限公司 | Rna聚合酶变体 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2400049C (en) * | 2000-03-07 | 2010-10-05 | Akzo Nobel N.V. | Rna polymerase mutants with increased thermostability |
| GB0611444D0 (en) * | 2006-06-09 | 2006-07-19 | Medical Res Council Technology | Rnase H2 complex and genes therefor |
| US9193959B2 (en) * | 2010-04-16 | 2015-11-24 | Roche Diagnostics Operations, Inc. | T7 RNA polymerase variants with enhanced thermostability |
| US20150376581A1 (en) * | 2012-10-29 | 2015-12-31 | Technische Universitaet Dortmund | T7 rna polymerase variants and methods of using the same |
| KR20160132113A (ko) * | 2014-03-20 | 2016-11-16 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 확장된 기질 범위 및 증진된 전사 수율을 갖는 t7 rna 폴리머라제 변이체 |
| CN116144626A (zh) * | 2016-01-13 | 2023-05-23 | 新英格兰生物实验室公司 | T7 rna聚合酶的热稳定变体 |
-
2019
- 2019-04-09 CN CN201980025099.1A patent/CN112218947A/zh active Pending
- 2019-04-09 WO PCT/US2019/026561 patent/WO2019199807A1/en not_active Ceased
- 2019-04-09 CA CA3095620A patent/CA3095620A1/en active Pending
- 2019-04-09 JP JP2020555861A patent/JP2021520815A/ja not_active Withdrawn
- 2019-04-09 EP EP19719092.9A patent/EP3775183A1/en not_active Withdrawn
- 2019-04-09 AU AU2019253693A patent/AU2019253693A1/en not_active Abandoned
- 2019-04-09 US US17/046,665 patent/US20210180034A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2021520815A5 (https=) | ||
| Carbonell et al. | Multi‐targeting of viral RNAs with synthetic trans‐acting small interfering RNAs enhances plant antiviral resistance | |
| Samuel | Adenosine deaminases acting on RNA (ADARs) are both antiviral and proviral | |
| US20250084397A1 (en) | Methods of purifying dna for gene synthesis | |
| Aguado et al. | RNase III nucleases from diverse kingdoms serve as antiviral effectors | |
| RU2015133046A (ru) | Двойной вектор для подавления вируса иммунодефицита человека | |
| JP2019510504A5 (https=) | ||
| Fajardo Jr et al. | Disruption of specific RNA-RNA interactions in a double-stranded RNA virus inhibits genome packaging and virus infectivity | |
| RU2017117510A (ru) | Редактирование целевой рнк | |
| JP2016530294A5 (https=) | ||
| WO2024010993A1 (en) | Primer design for cell-free dna production | |
| Sasai et al. | A novel non-segmented double-stranded RNA virus from an Arctic isolate of Pythium polare | |
| Geerts-Dimitriadou et al. | Analysis of the Tomato spotted wilt virus ambisense S RNA-encoded hairpin structure in translation | |
| Tao et al. | Genomic sequence of mandarin fish rhabdovirus with an unusual small non-transcriptional ORF | |
| Yang et al. | Analysis on the complete genome of a novel caprine parainfluenza virus 3 | |
| ES2550799T3 (es) | Análisis de tendencia en secuenciación | |
| Carbonell et al. | Design, synthesis, and functional analysis of highly specific artificial small RNAs with antiviral activity in plants | |
| EP4642912A1 (en) | Rna circularization | |
| Liu et al. | The porcine microRNA transcriptome response to transmissible gastroenteritis virus infection | |
| WO2016143799A1 (ja) | 無細胞タンパク質合成系に用いるための翻訳促進剤及びその利用 | |
| Luo et al. | Characterization of a wild rabies virus isolate of porcine origin in China | |
| US20230242958A1 (en) | Synthetic rna fragment and its uses for rna-dependent amplification | |
| CN110199025A (zh) | 用于无细胞蛋白质合成的启动子构建体 | |
| Fang et al. | Investigations on the tobacco necrosis virus D p60 replicase protein | |
| CN108624587A (zh) | 高效快速获取植物rna病毒末端序列的race方法 |