JP2021519100A5 - - Google Patents

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Publication number
JP2021519100A5
JP2021519100A5 JP2020552716A JP2020552716A JP2021519100A5 JP 2021519100 A5 JP2021519100 A5 JP 2021519100A5 JP 2020552716 A JP2020552716 A JP 2020552716A JP 2020552716 A JP2020552716 A JP 2020552716A JP 2021519100 A5 JP2021519100 A5 JP 2021519100A5
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JP
Japan
Prior art keywords
seq
antibody
amino acid
acid sequence
antigen
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020552716A
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English (en)
Japanese (ja)
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JP2021519100A (ja
JP7458569B2 (ja
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Priority claimed from GBGB1804860.3A external-priority patent/GB201804860D0/en
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Publication of JP2021519100A publication Critical patent/JP2021519100A/ja
Publication of JP2021519100A5 publication Critical patent/JP2021519100A5/ja
Application granted granted Critical
Publication of JP7458569B2 publication Critical patent/JP7458569B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020552716A 2018-03-27 2019-03-27 Cd47結合剤 Active JP7458569B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1804860.3A GB201804860D0 (en) 2018-03-27 2018-03-27 CD47 Binding agents
GB1804860.3 2018-03-27
GBGB1813693.7A GB201813693D0 (en) 2018-03-27 2018-08-22 CD47 binding agents
GB1813693.7 2018-08-22
PCT/EP2019/057723 WO2019185717A1 (en) 2018-03-27 2019-03-27 Cd47 binding agents

Publications (3)

Publication Number Publication Date
JP2021519100A JP2021519100A (ja) 2021-08-10
JP2021519100A5 true JP2021519100A5 (enExample) 2022-04-05
JP7458569B2 JP7458569B2 (ja) 2024-04-01

Family

ID=62068079

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020552716A Active JP7458569B2 (ja) 2018-03-27 2019-03-27 Cd47結合剤

Country Status (11)

Country Link
US (2) US12421310B2 (enExample)
EP (1) EP3774886A1 (enExample)
JP (1) JP7458569B2 (enExample)
KR (2) KR20260036010A (enExample)
CN (1) CN111936515B (enExample)
AU (2) AU2019246401B2 (enExample)
CA (1) CA3093777A1 (enExample)
GB (2) GB201804860D0 (enExample)
IL (1) IL277343B1 (enExample)
SG (1) SG11202008965SA (enExample)
WO (1) WO2019185717A1 (enExample)

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GB201804860D0 (en) 2018-03-27 2018-05-09 Ultrahuman Two Ltd CD47 Binding agents
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JP2022552748A (ja) 2019-10-31 2022-12-19 フォーティ セブン, インコーポレイテッド 抗cd47及び抗cd20による血液癌の治療
IL294032A (en) 2019-12-24 2022-08-01 Carna Biosciences Inc Compounds that regulate diacylglycerol kinase
TWI890283B (zh) 2020-02-14 2025-07-11 美商基利科學股份有限公司 結合ccr8之抗體及融合蛋白及其用途
CN115916963A (zh) 2020-03-27 2023-04-04 门德斯有限公司 白血病来源的经修饰细胞用于增强过继性细胞治疗的效力的离体用途
EP4171617A1 (en) 2020-06-30 2023-05-03 Mendus B.V. Use of leukemia-derived cells in ovarian cancer vaccines
US12071481B2 (en) 2020-12-23 2024-08-27 D-10 Therapeutics, Inc. Anti-CD47 antibodies and uses thereof
CA3212351A1 (en) 2021-03-12 2022-09-15 Mendus B.V. Methods of vaccination and use of cd47 blockade
TW202302145A (zh) 2021-04-14 2023-01-16 美商基利科學股份有限公司 CD47/SIRPα結合及NEDD8活化酶E1調節次單元之共抑制以用於治療癌症
AU2022299051B2 (en) 2021-06-23 2025-03-13 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
MX2023014762A (es) 2021-06-23 2024-01-15 Gilead Sciences Inc Compuestos moduladores de diacilglicerol quinasa.
JP7686091B2 (ja) 2021-06-23 2025-05-30 ギリアード サイエンシーズ, インコーポレイテッド ジアシルグリセロールキナーゼ調節化合物
JP7651018B2 (ja) 2021-06-23 2025-03-25 ギリアード サイエンシーズ, インコーポレイテッド ジアシルグリセロールキナーゼ調節化合物
AU2022375782B2 (en) 2021-10-28 2026-02-26 Gilead Sciences, Inc. Pyridizin-3(2h)-one derivatives
JP7787991B2 (ja) 2021-10-29 2025-12-17 ギリアード サイエンシーズ, インコーポレイテッド Cd73化合物
US12122764B2 (en) 2021-12-22 2024-10-22 Gilead Sciences, Inc. IKAROS zinc finger family degraders and uses thereof
KR20240123836A (ko) 2021-12-22 2024-08-14 길리애드 사이언시즈, 인코포레이티드 이카로스 아연 핑거 패밀리 분해제 및 이의 용도
TW202340168A (zh) 2022-01-28 2023-10-16 美商基利科學股份有限公司 Parp7抑制劑
WO2023178181A1 (en) 2022-03-17 2023-09-21 Gilead Sciences, Inc. Ikaros zinc finger family degraders and uses thereof
KR20240165995A (ko) 2022-03-24 2024-11-25 길리애드 사이언시즈, 인코포레이티드 Trop-2 발현 암의 치료를 위한 병용요법
TWI876305B (zh) 2022-04-05 2025-03-11 美商基利科學股份有限公司 用於治療結腸直腸癌之組合療法
CR20240451A (es) 2022-04-21 2024-12-04 Gilead Sciences Inc Compuestos de modulación de kras g12d
KR20250028371A (ko) 2022-07-01 2025-02-28 길리애드 사이언시즈, 인코포레이티드 Cd73 화합물
CA3259040A1 (en) 2022-07-12 2024-01-18 Gilead Sciences, Inc. HIV Immunogenic Polypeptides and Vaccines and Their Uses
WO2024064668A1 (en) 2022-09-21 2024-03-28 Gilead Sciences, Inc. FOCAL IONIZING RADIATION AND CD47/SIRPα DISRUPTION ANTICANCER COMBINATION THERAPY
AU2023409398A1 (en) 2022-12-22 2025-06-05 Gilead Sciences, Inc. Prmt5 inhibitors and uses thereof
AU2024252725A1 (en) 2023-04-11 2025-11-06 Gilead Sciences, Inc. Kras modulating compounds
CR20250446A (es) 2023-04-21 2025-12-02 Gilead Sciences Inc Inhibidores de prmt5 y usos de los mismos
AU2024306338A1 (en) 2023-06-30 2026-01-08 Gilead Sciences, Inc. Kras modulating compounds
CN121620513A (zh) 2023-07-26 2026-03-06 吉利德科学公司 Parp7抑制剂
KR20260046403A (ko) 2023-07-26 2026-04-07 길리애드 사이언시즈, 인코포레이티드 Parp7 저해제
US20250109147A1 (en) 2023-09-08 2025-04-03 Gilead Sciences, Inc. Kras g12d modulating compounds
US20250101042A1 (en) 2023-09-08 2025-03-27 Gilead Sciences, Inc. Kras g12d modulating compounds
US20250154172A1 (en) 2023-11-03 2025-05-15 Gilead Sciences, Inc. Prmt5 inhibitors and uses thereof
WO2025137640A1 (en) 2023-12-22 2025-06-26 Gilead Sciences, Inc. Azaspiro wrn inhibitors
WO2025245003A1 (en) 2024-05-21 2025-11-27 Gilead Sciences, Inc. Prmt5 inhibitors and uses thereof
US20260098049A1 (en) 2024-08-12 2026-04-09 Gilead Sciences, Inc. Kras modulating compounds

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US9221908B2 (en) 2012-12-12 2015-12-29 Vasculox, Inc. Therapeutic CD47 antibodies
BR112015013431A2 (pt) 2012-12-12 2017-11-14 Vasculox Inc anticorpos monoclonais ou respectivos fragmentos ligantes de antígenos, composição farmacêutica, e usos de anticorpo monoclonal ou respectivo fragmento ligante de antígenos
EP3221358B1 (en) 2014-11-18 2021-07-21 Janssen Pharmaceutica, N.V. Cd47 antibodies, methods, and uses
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WO2017053423A1 (en) 2015-09-21 2017-03-30 Erasmus University Medical Center Anti-cd47 antibodies and methods of use
PT3402820T (pt) * 2016-01-11 2020-08-20 Forty Seven Inc Anticorpos monoclonais anti-cd47 quiméricos, de ratinho ou humanizados
KR102505253B1 (ko) 2016-04-15 2023-03-02 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 암의 치료에서 항-cd47 제제의 치료적으로 효과적인 용량을 결정하고 달성하는 방법
CN111212852A (zh) 2017-08-18 2020-05-29 超人肆有限公司 结合剂
GB201804860D0 (en) 2018-03-27 2018-05-09 Ultrahuman Two Ltd CD47 Binding agents

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