JP2021517826A5 - - Google Patents
Info
- Publication number
- JP2021517826A5 JP2021517826A5 JP2020568663A JP2020568663A JP2021517826A5 JP 2021517826 A5 JP2021517826 A5 JP 2021517826A5 JP 2020568663 A JP2020568663 A JP 2020568663A JP 2020568663 A JP2020568663 A JP 2020568663A JP 2021517826 A5 JP2021517826 A5 JP 2021517826A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide according
- oligonucleotide
- nucleotides
- antisense
- length
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862637574P | 2018-03-02 | 2018-03-02 | |
| US62/637,574 | 2018-03-02 | ||
| PCT/US2019/018189 WO2019168687A1 (en) | 2018-03-02 | 2019-02-15 | Compositions and methods for inhibiting gys2 expression |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021517826A JP2021517826A (ja) | 2021-07-29 |
| JPWO2019168687A5 JPWO2019168687A5 (https=) | 2022-02-24 |
| JP2021517826A5 true JP2021517826A5 (https=) | 2022-02-24 |
| JP7453921B2 JP7453921B2 (ja) | 2024-03-21 |
Family
ID=67805080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020568663A Active JP7453921B2 (ja) | 2018-03-02 | 2019-02-15 | Ｇｙｓ２発現を阻害するための組成物及び方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11572562B2 (https=) |
| EP (1) | EP3740247A4 (https=) |
| JP (1) | JP7453921B2 (https=) |
| KR (1) | KR102804353B1 (https=) |
| CN (1) | CN112055598B (https=) |
| AU (1) | AU2019227510B2 (https=) |
| CA (1) | CA3092092A1 (https=) |
| IL (2) | IL325191A (https=) |
| MX (1) | MX2020009072A (https=) |
| WO (1) | WO2019168687A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019227510B2 (en) | 2018-03-02 | 2026-02-12 | Novo Nordisk A/S | Compositions and methods for inhibiting GYS2 expression |
| WO2020226960A1 (en) | 2019-05-03 | 2020-11-12 | Dicerna Pharmaceuticals, Inc. | Double-stranded nucleic acid inhibitor molecules with shortened sense strands |
| WO2022223515A2 (en) * | 2021-04-19 | 2022-10-27 | Novo Nordisk A/S | Compositions and methods for inhibiting nuclear receptor subfamily 1 group h member 3 (nr1h3) expression |
| AU2024269205A1 (en) * | 2023-05-11 | 2025-12-11 | Keymed Biosciences (Us) Inc. | Dsrna molecules for regulating masp2 gene activity |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030004122A1 (en) * | 1997-11-05 | 2003-01-02 | Leonid Beigelman | Nucleotide triphosphates and their incorporation into oligonucleotides |
| US6436703B1 (en) | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| EP2305812A3 (en) * | 2002-11-14 | 2012-06-06 | Dharmacon, Inc. | Fuctional and hyperfunctional sirna |
| US20050119210A1 (en) * | 2003-05-20 | 2005-06-02 | Xiaobing Be | Compositions and methods for diagnosing and treating cancers |
| US20060078902A1 (en) * | 2004-04-15 | 2006-04-13 | Michaeline Bunting | Method and compositions for RNA interference |
| EP1752536A4 (en) * | 2004-05-11 | 2008-04-16 | Alphagen Co Ltd | POLYNUCLEOTIDE CAUSING RNA INTERFERENCE AND METHOD OF REGULATING GENE EXPRESSION WITH THE USE OF THE SAME |
| US8278287B2 (en) * | 2008-04-15 | 2012-10-02 | Quark Pharmaceuticals Inc. | siRNA compounds for inhibiting NRF2 |
| JP2012504389A (ja) * | 2008-09-22 | 2012-02-23 | ダイセルナ ファーマシューティカルズ， インコーポレイテッド | 修飾を有するｄｓＲＮＡによる遺伝子発現の特異的な阻害のための組成物および方法 |
| AU2009336191B2 (en) * | 2008-12-18 | 2017-08-24 | Novo Nordisk A/S | Extended dicer substrate agents and methods for the specific inhibition of gene expression |
| WO2010105372A1 (en) | 2009-03-20 | 2010-09-23 | Protiva Biotherapeutics, Inc. | Compositions and methods for silencing hepatitis c virus expression |
| US8999950B2 (en) * | 2011-10-05 | 2015-04-07 | Protiva Biotherapeutics Inc. | Compositions and methods for silencing aldehyde dehydrogenase |
| AU2015330670B2 (en) * | 2014-10-10 | 2022-01-06 | Novo Nordisk Health Care Ag | Therapeutic inhibition of lactate dehydrogenase and agents therefor |
| JP7105065B2 (ja) * | 2014-12-15 | 2022-07-22 | ダイセルナ ファーマシューティカルズ， インコーポレイテッド | リガンド修飾二本鎖核酸 |
| US10689647B2 (en) | 2015-05-08 | 2020-06-23 | Dicerna Pharmaceuticals, Inc. | Methods and compositions for the specific inhibition of antithrombin 3 (AT3) by double-stranded RNA |
| WO2017141109A1 (en) * | 2016-02-18 | 2017-08-24 | Crispr Therapeutics Ag | Materials and methods for treatment of severe combined immunodeficiency (scid) or omenn syndrome |
| CN111448316B (zh) * | 2017-12-22 | 2025-02-14 | 罗氏创新中心哥本哈根有限公司 | 新的硫代亚磷酰胺 |
| AU2019227510B2 (en) | 2018-03-02 | 2026-02-12 | Novo Nordisk A/S | Compositions and methods for inhibiting GYS2 expression |
-
2019
- 2019-02-15 AU AU2019227510A patent/AU2019227510B2/en active Active
- 2019-02-15 EP EP19760244.4A patent/EP3740247A4/en active Pending
- 2019-02-15 KR KR1020207027734A patent/KR102804353B1/ko active Active
- 2019-02-15 US US16/977,152 patent/US11572562B2/en active Active
- 2019-02-15 MX MX2020009072A patent/MX2020009072A/es unknown
- 2019-02-15 WO PCT/US2019/018189 patent/WO2019168687A1/en not_active Ceased
- 2019-02-15 CA CA3092092A patent/CA3092092A1/en active Pending
- 2019-02-15 JP JP2020568663A patent/JP7453921B2/ja active Active
- 2019-02-15 CN CN201980029587.XA patent/CN112055598B/zh active Active
- 2019-02-15 IL IL325191A patent/IL325191A/en unknown
-
2020
- 2020-08-31 IL IL277058A patent/IL277058A/en unknown
-
2023
- 2023-01-18 US US18/156,177 patent/US12534730B2/en active Active
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