JP2021516957A - パラポックスウイルスベクター - Google Patents

パラポックスウイルスベクター Download PDF

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Publication number
JP2021516957A
JP2021516957A JP2020546320A JP2020546320A JP2021516957A JP 2021516957 A JP2021516957 A JP 2021516957A JP 2020546320 A JP2020546320 A JP 2020546320A JP 2020546320 A JP2020546320 A JP 2020546320A JP 2021516957 A JP2021516957 A JP 2021516957A
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JP
Japan
Prior art keywords
pcpv
virus
cells
antigen
polypeptide
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JP2020546320A
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English (en)
Japanese (ja)
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JP2021516957A5 (https=
Inventor
カローラ、リットナー
クリステル、レミ
クリスティーヌ、チウデレ
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Transgene SA
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Transgene SA
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Application filed by Transgene SA filed Critical Transgene SA
Publication of JP2021516957A publication Critical patent/JP2021516957A/ja
Publication of JP2021516957A5 publication Critical patent/JP2021516957A5/ja
Priority to JP2024001510A priority Critical patent/JP2024050588A/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001169—Tumor associated carbohydrates
    • A61K39/00117—Mucins, e.g. MUC-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/20043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24211—Parapoxvirus, e.g. Orf virus
    • C12N2710/24241—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24243—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2020546320A 2018-03-07 2019-03-07 パラポックスウイルスベクター Pending JP2021516957A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024001510A JP2024050588A (ja) 2018-03-07 2024-01-09 パラポックスウイルスベクター

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP18305237.2 2018-03-07
EP18305237 2018-03-07
EP18306424 2018-10-31
EP18306424.5 2018-10-31
PCT/EP2019/055744 WO2019170820A1 (en) 2018-03-07 2019-03-07 Parapoxvirus vectors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024001510A Division JP2024050588A (ja) 2018-03-07 2024-01-09 パラポックスウイルスベクター

Publications (2)

Publication Number Publication Date
JP2021516957A true JP2021516957A (ja) 2021-07-15
JP2021516957A5 JP2021516957A5 (https=) 2022-03-15

Family

ID=65628796

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020546320A Pending JP2021516957A (ja) 2018-03-07 2019-03-07 パラポックスウイルスベクター
JP2024001510A Pending JP2024050588A (ja) 2018-03-07 2024-01-09 パラポックスウイルスベクター

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024001510A Pending JP2024050588A (ja) 2018-03-07 2024-01-09 パラポックスウイルスベクター

Country Status (10)

Country Link
US (1) US12377142B2 (https=)
EP (1) EP3762020A1 (https=)
JP (2) JP2021516957A (https=)
CN (1) CN112512560A (https=)
AU (1) AU2019229653B2 (https=)
BR (1) BR112020018117A2 (https=)
CA (1) CA3093093A1 (https=)
IL (1) IL277161A (https=)
MX (1) MX2020009262A (https=)
WO (1) WO2019170820A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021258008A1 (en) * 2020-06-19 2021-12-23 Immunacor Llc Compositions and methods for treating and preventing viral infection
WO2023083951A1 (en) * 2021-11-10 2023-05-19 Aicuris Gmbh & Co. Kg Parapoxvirus for preparing for and treatment of respiratory syncytial virus infections
WO2024062098A1 (en) 2022-09-23 2024-03-28 Transgene Recombinant pseudocowpox virus encoding an interleukin-12
CN116121207B (zh) * 2023-02-08 2025-12-12 华南农业大学 一种表达猪圆环病毒3型Cap蛋白的重组羊口疮病毒及其制备方法和应用
WO2024178260A2 (en) * 2023-02-22 2024-08-29 Cornell University Systems and methods for heterologous gene expression by poxvirus vectors
CN116897887A (zh) * 2023-07-31 2023-10-20 湖南中医药大学 一种病毒性哮喘动物模型的构建方法

Citations (6)

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JP2000507092A (ja) * 1996-02-28 2000-06-13 バイエル・アクチエンゲゼルシヤフト 外来ｄｎａを含むパラポックスウイルス、それらの製造及びワクチンにおけるそれらの使用
JP2009540806A (ja) * 2006-06-20 2009-11-26 トランジェーヌ、ソシエテ、アノニム ポックスウイルスおよびポックスウイルス組成物の製造方法
JP2013537409A (ja) * 2010-07-20 2013-10-03 ゾエティス・エルエルシー パラポックスウイルスベクター
WO2016128542A1 (en) * 2015-02-13 2016-08-18 Transgene Sa Immunotherapeutic vaccine and antibody combination therapy
WO2017013023A1 (de) * 2015-07-20 2017-01-26 Eberhard Karls Universitaet Tuebingen Medizinische Fakultaet Rekombinanter orf-virus-vektor
WO2018031694A1 (en) * 2016-08-09 2018-02-15 City Of Hope Chimeric poxvirus compositions and uses thereof

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US5250534A (en) 1990-06-20 1993-10-05 Pfizer Inc. Pyrazolopyrimidinone antianginal agents
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Publication number Priority date Publication date Assignee Title
JP2000507092A (ja) * 1996-02-28 2000-06-13 バイエル・アクチエンゲゼルシヤフト 外来ｄｎａを含むパラポックスウイルス、それらの製造及びワクチンにおけるそれらの使用
JP2009540806A (ja) * 2006-06-20 2009-11-26 トランジェーヌ、ソシエテ、アノニム ポックスウイルスおよびポックスウイルス組成物の製造方法
JP2013537409A (ja) * 2010-07-20 2013-10-03 ゾエティス・エルエルシー パラポックスウイルスベクター
WO2016128542A1 (en) * 2015-02-13 2016-08-18 Transgene Sa Immunotherapeutic vaccine and antibody combination therapy
WO2017013023A1 (de) * 2015-07-20 2017-01-26 Eberhard Karls Universitaet Tuebingen Medizinische Fakultaet Rekombinanter orf-virus-vektor
WO2018031694A1 (en) * 2016-08-09 2018-02-15 City Of Hope Chimeric poxvirus compositions and uses thereof

Also Published As

Publication number Publication date
US20210000937A1 (en) 2021-01-07
AU2019229653B2 (en) 2025-09-11
WO2019170820A9 (en) 2020-05-28
WO2019170820A1 (en) 2019-09-12
BR112020018117A2 (pt) 2020-12-22
CA3093093A1 (en) 2019-09-12
EP3762020A1 (en) 2021-01-13
US12377142B2 (en) 2025-08-05
AU2019229653A1 (en) 2020-09-24
CN112512560A (zh) 2021-03-16
IL277161A (en) 2020-10-29
MX2020009262A (es) 2021-01-08
JP2024050588A (ja) 2024-04-10

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