JP2021516222A5 - - Google Patents

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Publication number
JP2021516222A5
JP2021516222A5 JP2020542898A JP2020542898A JP2021516222A5 JP 2021516222 A5 JP2021516222 A5 JP 2021516222A5 JP 2020542898 A JP2020542898 A JP 2020542898A JP 2020542898 A JP2020542898 A JP 2020542898A JP 2021516222 A5 JP2021516222 A5 JP 2021516222A5
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JP
Japan
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leu
ala
trp
exist
arg
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Pending
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JP2020542898A
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English (en)
Japanese (ja)
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JP2021516222A (ja
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Priority claimed from PCT/US2019/022439 external-priority patent/WO2019178462A1/en
Publication of JP2021516222A publication Critical patent/JP2021516222A/ja
Publication of JP2021516222A5 publication Critical patent/JP2021516222A5/ja
Pending legal-status Critical Current

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JP2020542898A 2018-03-16 2019-03-15 副甲状腺ホルモンポリペプチドコンジュゲートおよびその使用方法 Pending JP2021516222A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862644316P 2018-03-16 2018-03-16
US62/644,316 2018-03-16
PCT/US2019/022439 WO2019178462A1 (en) 2018-03-16 2019-03-15 Parathyroid hormone polypeptide conjugates and methods of their use

Publications (2)

Publication Number Publication Date
JP2021516222A JP2021516222A (ja) 2021-07-01
JP2021516222A5 true JP2021516222A5 (enExample) 2022-03-23

Family

ID=67908395

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020542898A Pending JP2021516222A (ja) 2018-03-16 2019-03-15 副甲状腺ホルモンポリペプチドコンジュゲートおよびその使用方法

Country Status (4)

Country Link
US (1) US11975050B2 (enExample)
EP (1) EP3765061A4 (enExample)
JP (1) JP2021516222A (enExample)
WO (1) WO2019178462A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022024058A2 (pt) * 2020-05-26 2022-12-20 Univ Indiana Res & Tech Corp Análogos de pth para o tratamento de hipoparatireoidismo
EP4593867A2 (en) 2022-09-30 2025-08-06 Extend Biosciences, Inc. Long-acting parathyroid hormone
WO2025250793A1 (en) * 2024-05-29 2025-12-04 The General Hospital Corporation Parathyroid hormone polypeptide conjugates and methods of their use
WO2026067798A1 (zh) * 2024-09-30 2026-04-02 长春金赛药业有限责任公司 Pth复合物及其应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
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WO1992017602A1 (en) 1991-04-05 1992-10-15 The General Hospital Corporation Office Of Technology Affairs Parathyroid hormone receptor and dna encoding same
US7150974B1 (en) 1991-04-05 2006-12-19 The General Hospital Corporation Parathyroid hormone receptor binding method
US7132260B2 (en) 1991-04-05 2006-11-07 The General Hospital Corporation DNA encoding parathyroid hormone receptor
US5261686A (en) 1992-04-06 1993-11-16 Buckler Clive E Semi-recumbent
AU3819497A (en) 1996-07-31 1998-02-20 General Hospital Corporation, The Novel parathyroid hormone-related peptide analogs
US6183974B1 (en) 1997-07-31 2001-02-06 The General Hospital Corporation Screening assays for G protein coupled receptor agonists and antagonists
WO2000023594A1 (en) 1998-10-22 2000-04-27 The General Hospital Corporation BIOACTIVE PEPTIDES AND PEPTIDE DERIVATIVES OF PARATHYROID HORMONE (PTH) AND PARATHYROID HORMONE-RELATED PEPTIDE (PTHrP)
ATE384743T1 (de) 1998-11-25 2008-02-15 Gen Hospital Corp Aminoterminal modifizierte parathyroidhormon (pth) analoge
JP4486258B2 (ja) 1998-11-25 2010-06-23 ザ・ジェネラル・ホスピタル・コーポレイション ヒト副甲状腺ホルモンの改変、調製および使用
WO2000032771A1 (en) 1998-11-30 2000-06-08 The General Hospital Corporation Pth1r and pth3r receptors, methods and uses thereof
US7057012B1 (en) 1998-12-31 2006-06-06 The General Hospital Corporation PTH functional domain conjugate peptides, derivatives thereof and novel tethered ligand-receptor molecules
ATE308609T1 (de) 1998-12-31 2005-11-15 Gen Hospital Corp Pth rezeptor und testverfahren unter verwendung desselben
WO2001023521A2 (en) 1999-09-29 2001-04-05 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (pth)
US7022815B1 (en) 1999-09-29 2006-04-04 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (PTH)
WO2003009804A2 (en) 2001-07-23 2003-02-06 The General Hospital Corporation Conformationally constrained parathyroid hormone (pth) analogs
US7087229B2 (en) * 2003-05-30 2006-08-08 Enzon Pharmaceuticals, Inc. Releasable polymeric conjugates based on aliphatic biodegradable linkers
WO2004067021A1 (en) 2003-01-24 2004-08-12 Gardella Thomas J Conformationally constrained parathyroid hormone (pth) analogs with lactam bridges
WO2004093902A1 (en) 2003-03-19 2004-11-04 The General Hospital Corporation CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONES WITH α-HELIX STABILIZERS
US7910544B2 (en) 2003-07-17 2011-03-22 The General Hospital Corporation Conformationally constrained parthyroid hormone (PTH) analogs
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EP1755651B1 (en) * 2004-06-14 2016-10-12 BASF Beauty Care Solutions S.A.S. Cosmetic preparations containing pth fragments
JP2009545320A (ja) 2006-08-04 2009-12-24 ザ ジェネラル ホスピタル コーポレイション 副甲状腺ホルモン（ｐｔｈ）のポリペプチド誘導体
CN101784281B (zh) 2007-08-01 2014-07-02 总医院有限公司 确定g蛋白偶联受体激动剂的方法
US20110294738A1 (en) * 2008-11-04 2011-12-01 Yong Ren Pthr1 receptor compounds
EP2411038B1 (en) 2009-03-27 2016-12-28 Van Andel Research Institute Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
US9492508B2 (en) 2010-05-13 2016-11-15 The General Hospital Corporation Parathyroid hormone analogs and uses thereof
IL317744A (en) * 2016-03-01 2025-02-01 Ascendis Pharma Bone Diseases As PTH drug agonists
WO2017173372A1 (en) * 2016-04-01 2017-10-05 The General Hospital Corporation Parathyroid hormone receptor 1 antagonist and inverse agonist polypeptides and methods of their use
PL3518961T3 (pl) * 2016-09-29 2023-08-14 Ascendis Pharma Bone Diseases A/S Związki pth o niskim stosunku wartości maksymalnej do minimalnej
KR101964376B1 (ko) * 2017-09-29 2019-04-01 주식회사 나이벡 부갑상선호르몬(parathyroid hormone, PTH)에 골조직 선택성 펩타이드가 결합되어 있는 융합 펩타이드를 포함하는 약학 조성물 및 생체재료

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